Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury

European Journal of Immunology

Volumn 39, Issue 6, 2009, Pages 1652-1663

  Njoku, Dolore B ^a   Li, Zhaoxia ^a   Washington, Nicole D ^a   Mellerson, Jenelle L ^a   Talor, Monica V ^a   Sharma, Rajni ^a   Rose, Noel R ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Cytochrome P450 2E1; Drug induced liver injury; Idiosyncratic acute liver failure; IL 4; Trifluoroacetyl chloride

Indexed keywords

ALCOHOL; ANESTHETIC AGENT; CARBAMAZEPINE; CYTOCHROME P450 2E1; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN G4; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; PROTEIN ANTIBODY; PROTEIN S 100; ANTIBODY; DRUG DERIVATIVE; HOMEODOMAIN PROTEIN; RAG 1 PROTEIN; RAG-1 PROTEIN; TRIFLUOROACETIC ACID; TRIFLUOROACETYL CHLORIDE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOPATHOGENESIS; LIVER INJURY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL; SUPERNATANT; T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; BLOOD; CD4+ T LYMPHOCYTE; CYTOLOGY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOLOGY; LIVER; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; NATURAL KILLER CELL; NATURAL KILLER T CELL; PATHOLOGY; REGULATORY T LYMPHOCYTE; TH1 CELL; TH2 CELL; TOXIC HEPATITIS; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; CYTOCHROME P-450 CYP2E1; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HEPATITIS, TOXIC; HOMEODOMAIN PROTEINS; INTERLEUKIN-10; INTERLEUKIN-4; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; NATURAL KILLER T-CELLS; S100 PROTEINS; SPLEEN; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS; TRIFLUOROACETIC ACID;

EID: 67649528154     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838135     Document Type: Article

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