Augmentation of the antimicrobial activities of guinea pig cathelicidin CAP11-derived peptides by amino acid substitutions

International Journal of Molecular Medicine

Volumn 23, Issue 4, 2009, Pages 501-508

  Okuda, Daiju ^a   Yomogida, Shin ^a   Kuwahara Arai, Kyoko ^a   Hitamatsu, Keiichi ^a   Tamura, Hiroshi ^b   Nagaoka, Isao ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Seikagaku Biobusiness Corporation   (Japan)

Author keywords

Antimicrobial host defense peptide; Cathelicidin; Guinea pig

Indexed keywords

ARGININE; CATHELICIDIN ANTIMICROBIAL PEPTIDE CAP11; GLYCINE; LEUCINE; LYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CHEMICAL MODIFICATION; COLONY FORMATION; CONTROLLED STUDY; DNA TEMPLATE; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; ESCHERICHIA COLI; GUINEA PIG; HYDROPHILICITY; HYDROPHOBICITY; MEMBRANE PERMEABILITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; RESIDUE ANALYSIS; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BACILLUS SUBTILIS; BETA-GALACTOSIDASE; BETA-LACTAMASES; CELL MEMBRANE PERMEABILITY; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GUINEA PIGS; HYDROPHOBICITY; MOLECULAR SEQUENCE DATA; PEPTIDES; PERIPLASM; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 67649424250     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000157     Document Type: Article

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