메뉴 건너뛰기




Volumn 2, Issue 2, 2008, Pages 255-260

Effects of exenatide on diabetes, obesity, cardiovascular risk factors, and hepatic biomarkers in patients with type 2 diabetes

Author keywords

Exenatide; NAFLD; Obesity; Type 2 diabetes

Indexed keywords


EID: 67649373364     PISSN: None     EISSN: 19322968     Source Type: Journal    
DOI: 10.1177/193229680800200214     Document Type: Review
Times cited : (16)

References (37)
  • 1
    • 0141988862 scopus 로고    scopus 로고
    • Importance of weight management in type 2 diabetes: Review with meta-analysis of clinical studies
    • Anderson JW, Kendall CW, Jenkins DJ. Importance of weight management in type 2 diabetes: review with meta-analysis of clinical studies. J Am Coll Nutr. 2003;22(5):331-9.
    • (2003) J Am Coll Nutr. , vol.22 , Issue.5 , pp. 331-339
    • Anderson, J.W.1    Kendall, C.W.2    Jenkins, D.J.3
  • 6
    • 2942657650 scopus 로고    scopus 로고
    • Medical consequences of obesity
    • Bray GA. Medical consequences of obesity. J Clin Endocrinol Metab. 2004;89(6):2583-9.
    • (2004) J Clin Endocrinol Metab. , vol.89 , Issue.6 , pp. 2583-2589
    • Bray, G.A.1
  • 7
    • 18644379136 scopus 로고    scopus 로고
    • The fatty liver and insulin resistance
    • Yki-Järvinen H, Westerbacka J. The fatty liver and insulin resistance. Curr Mol Med. 2005;5(3):287-95.
    • (2005) Curr Mol Med. , vol.5 , Issue.3 , pp. 287-295
    • Yki-Järvinen, H.1    Westerbacka, J.2
  • 9
    • 34249332073 scopus 로고    scopus 로고
    • Emerging therapies for type 2 diabetes
    • Stonehouse AH, Maggs DG. Emerging therapies for type 2 diabetes. Curr Drug Ther. 2007;2:151-60.
    • (2007) Curr Drug Ther. , vol.2 , pp. 151-160
    • Stonehouse, A.H.1    Maggs, D.G.2
  • 10
    • 0028817815 scopus 로고
    • Overview of 6 years' therapy of type II diabetes: A progressive disease. U. K. Prospective Diabetes Study Group
    • U. K. prospective diabetes study 16
    • U. K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U. K. Prospective Diabetes Study Group. Diabetes. 1995;44(11):1249 58.
    • (1995) Diabetes. , vol.44 , Issue.11 , pp. 1249-1258
  • 11
    • 0042861368 scopus 로고    scopus 로고
    • Weight effect of current and experimental drugs for diabetes mellitus: From prevention to alleviation of obesity
    • Purnell JQ, Weyer C. Weight effect of current and experimental drugs for diabetes mellitus: from prevention to alleviation of obesity.. Treat Endocrinol. 2003;2(1):33-47.
    • (2003) Treat Endocrinol. , vol.2 , Issue.1 , pp. 33-47
    • Purnell, J.Q.1    Weyer, C.2
  • 12
  • 13
    • 0036829752 scopus 로고    scopus 로고
    • American Gastroenterological Association medical position statement: Nonalcoholic fatty liver disease
    • American Gastroenterological Association medical position statement: nonalcoholic fatty liver disease.. Gastroenterology. 2002;123(5):1702-4.
    • (2002) Gastroenterology. , vol.123 , Issue.5 , pp. 1702-1704
  • 14
    • 12744279669 scopus 로고    scopus 로고
    • Diabetes: Insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage
    • Raz I, Eldor R, Cernea S, Shafrir E. Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage. Diabetes Metab Res Rev. 2005;21(1):3-14.
    • (2005) Diabetes Metab Res Rev. , vol.21 , Issue.1 , pp. 3-14
    • Raz, I.1    Eldor, R.2    Cernea, S.3    Shafrir, E.4
  • 15
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • Targher G, Bertolini L, Padovani R, Rodella S, Tessari R, Zenari L, Day C, Arcaro G. Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients.. Diabetes Care. 2007;30(5):1212-8.
    • (2007) Diabetes Care. , vol.30 , Issue.5 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Rodella, S.4    Tessari, R.5    Zenari, L.6    Day, C.7    Arcaro, G.8
  • 16
    • 0026648961 scopus 로고
    • Isolation and characterization of exendin-4, an exendin-3 analogue from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
    • Eng J, Kleinman WA, Singh L, Singh G, Raufman JP. Isolation and characterization of exendin-4, an exendin-3 analogue from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem. 1992;267(11):7402-5.
    • (1992) J Biol Chem. , vol.267 , Issue.11 , pp. 7402-7405
    • Eng, J.1    Kleinman, W.A.2    Singh, L.3    Singh, G.4    Raufman, J.P.5
  • 17
    • 0347081275 scopus 로고    scopus 로고
    • Glucagon-like peptide-1, exendin and insulin sensitivity
    • Hansen B, Shafrir E, editors, New York: Harwood Academic Press
    • Young AA. Glucagon-like peptide-1, exendin and insulin sensitivity. In: Hansen B, Shafrir E, editors. Insulin resistance and insulin resistance syndrome. New York: Harwood Academic Press; 2002. p. 235-62.
    • (2002) Insulin Resistance and Insulin Resistance Syndrome , pp. 235-262
    • Young, A.A.1
  • 18
    • 0035340019 scopus 로고    scopus 로고
    • Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
    • Parkes DG, Pittner R, Jodka C, Smith P, Young A. Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism. 2001;50(5):583-9.
    • (2001) Metabolism. , vol.50 , Issue.5 , pp. 583-589
    • Parkes, D.G.1    Pittner, R.2    Jodka, C.3    Smith, P.4    Young, A.5
  • 19
    • 33845273098 scopus 로고    scopus 로고
    • Exenatide effects on glucose metabolism and metabolic disorders common to overweight and obese patients with type 2 diabetes
    • Webb DM, Wintle M, Malone JK. Exenatide effects on glucose metabolism and metabolic disorders common to overweight and obese patients with type 2 diabetes.. Drug Dev Res. 2006;67(8):666-76.
    • (2006) Drug Dev Res. , vol.67 , Issue.8 , pp. 666-676
    • Webb, D.M.1    Wintle, M.2    Malone, J.K.3
  • 20
    • 34247195226 scopus 로고    scopus 로고
    • A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: A non-inferiority study
    • Nauck MA, Duran S, Kim D, Johns D, Northrup J, Festa A, Brodows R, Trautmann M. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study.. Diabetologia. 2007;50(2):259-67.
    • (2007) Diabetologia. , vol.50 , Issue.2 , pp. 259-267
    • Nauck, M.A.1    Duran, S.2    Kim, D.3    Johns, D.4    Northrup, J.5    Festa, A.6    Brodows, R.7    Trautmann, M.8
  • 22
    • 33845192364 scopus 로고    scopus 로고
    • Therapeutic applications of incretin mimetics for metabolic diseases: Preclinical studies
    • Mack C, Laugero K, Liu Q, Jodka C, Young A, Parkes D. Therapeutic applications of incretin mimetics for metabolic diseases: preclinical studies. Drug Dev Res. 2006;67(7):553-8.
    • (2006) Drug Dev Res. , vol.67 , Issue.7 , pp. 553-558
    • Mack, C.1    Laugero, K.2    Liu, Q.3    Jodka, C.4    Young, A.5    Parkes, D.6
  • 23
    • 0031040794 scopus 로고    scopus 로고
    • Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard
    • Chen YE, Drucker DJ. Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard.. J Biol Chem. 1997;272(7):4108-15.
    • (1997) J Biol Chem. , vol.272 , Issue.7 , pp. 4108-4115
    • Chen, Y.E.1    Drucker, D.J.2
  • 26
    • 0347360186 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
    • Nielsen LL, Young AA, Parkes D. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes.. Regul Pept. 2004;117(2):77-88.
    • (2004) Regul Pept. , vol.117 , Issue.2 , pp. 77-88
    • Nielsen, L.L.1    Young, A.A.2    Parkes, D.3
  • 27
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes.. Diabetes Care. 2004;27(11):2628-35.
    • (2004) Diabetes Care. , vol.27 , Issue.11 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 28
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • De Fronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes.. Diabetes Care. 2005;28(5):1092-100.
    • (2005) Diabetes Care. , vol.28 , Issue.5 , pp. 1092-1100
    • De Fronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 29
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall DM, Riddle MC, Rosenstock J, Zhuang D, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea.. Diabetes Care. 2005;28(5):1083-91.
    • (2005) Diabetes Care. , vol.28 , Issue.5 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3    Zhuang, D.4    Kim, D.D.5    Fineman, M.S.6    Baron, A.D.7
  • 30
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, Zhang B, MacSM, Poon TH, Taylor KL, Trautmann ME, Kim DD, Kendall DM. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes.. Diabetes Obes Metab. 2006;8(4):436-47.
    • (2006) Diabetes Obes Metab. , vol.8 , Issue.4 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5    Poon, T.H.6    Taylor, K.L.7    Trautmann, M.E.8    Kim, D.D.9    Kendall, D.M.10
  • 31
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three doubleblind, placebo-controlled trials
    • Buse JB, Klonoff DC, Nielsen LL, Guan X, Bowlus CL, Holcombe JH, Maggs DG, Wintle ME. Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three doubleblind, placebo-controlled trials.. Clin Ther. 2007;29(1):139-53.
    • (2007) Clin Ther. , vol.29 , Issue.1 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3    Guan, X.4    Bowlus, C.L.5    Holcombe, J.H.6    Maggs, D.G.7    Wintle, M.E.8
  • 32
    • 38549162147 scopus 로고    scopus 로고
    • Exenatide effects on diabetes, obesity, cardiovascular risk factors, and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
    • Klonoff DC, Buse JB, Nielsen LL, Guan X, Bowlus CL, Holcombe JH, Wintle ME, Maggs DG. Exenatide effects on diabetes, obesity, cardiovascular risk factors, and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years.. Curr Med Res Opin. 2008;24(1):275-86.
    • (2008) Curr Med Res Opin. , vol.24 , Issue.1 , pp. 275-286
    • Klonoff, D.C.1    Buse, J.B.2    Nielsen, L.L.3    Guan, X.4    Bowlus, C.L.5    Holcombe, J.H.6    Wintle, M.E.7    Maggs, D.G.8
  • 34
    • 33644803761 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
    • Ding X, Saxena NK, Lin S, Gupta N, Anania FA. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice.. Hepatology. 2006;43(1):173-81.
    • (2006) Hepatology. , vol.43 , Issue.1 , pp. 173-181
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Gupta, N.4    Anania, F.A.5
  • 35
    • 26944477362 scopus 로고    scopus 로고
    • Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes
    • GWAA Study Group
    • Heine RJ, Van Gaal LF, Johns D, Mihm MJ, Widel MH, Brodows RG; GWAA Study Group. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes. Ann Intern Med. 2005;143(8):559-569.
    • (2005) Ann Intern Med. , vol.143 , Issue.8 , pp. 559-569
    • Heine, R.J.1    Van Gaal, L.F.2    Johns, D.3    Mihm, M.J.4    Widel, M.H.5    Brodows, R.G.6
  • 36
    • 34249891874 scopus 로고    scopus 로고
    • Effects of once-weekly dosing of a longacting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
    • Kim D, MacConell L, Zhuang D, Kothare PA, Trautmann M, Fineman M, Taylor K. Effects of once-weekly dosing of a longacting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes.. Diabetes Care. 2007;30(6):1487-93.
    • (2007) Diabetes Care. , vol.30 , Issue.6 , pp. 1487-1493
    • Kim, D.1    MacConell, L.2    Zhuang, D.3    Kothare, P.A.4    Trautmann, M.5    Fineman, M.6    Taylor, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.