-
1
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N et al: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med (2004) 350(23):2335-2342.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
-
2
-
-
52949129894
-
Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American Academy of Ophthalmology
-
American Academy of Ophthalmology
-
Ip MS, Scott IU, Brown GC, Brown MM, Ho AC, Huang SS, Recchia FM, American Academy of Ophthalmology: Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American Academy of Ophthalmology. Ophthalmology (2008) 115(10):1837- 1846.
-
(2008)
Ophthalmology
, vol.115
, Issue.10
, pp. 1837-1846
-
-
Ip, M.S.1
Scott, I.U.2
Brown, G.C.3
Brown, M.M.4
Ho, A.C.5
Huang, S.S.6
Recchia, F.M.7
-
3
-
-
0028216495
-
Vascular permeability factor/endothelial growth factor (VPF/VEGF): Accumulation and expression in human synovial fluids and rheumatoid synovial tissue
-
Fava RA, Olsen NJ, Spencer-Green G, Yeo KT, Yeo TK, Berse B, Jackman RW, Senger DR, Dvorak HF, Brown LF: Vascular permeability factor/endothelial growth factor (VPF/VEGF): Accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med (1994) 180(1):341- 346.
-
(1994)
J Exp Med
, vol.180
, Issue.1
, pp. 341-346
-
-
Fava, R.A.1
Olsen, N.J.2
Spencer-Green, G.3
Yeo, K.T.4
Yeo, T.K.5
Berse, B.6
Jackman, R.W.7
Senger, D.R.8
Dvorak, H.F.9
Brown, L.F.10
-
4
-
-
0033786484
-
Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis
-
Nagashima M, Asano G, Yoshino S: Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis. J Rheumatol (2000) 27(10):2339-2342.
-
(2000)
J Rheumatol
, vol.27
, Issue.10
, pp. 2339-2342
-
-
Nagashima, M.1
Asano, G.2
Yoshino, S.3
-
5
-
-
0347719258
-
The transcription factors hypoxia-inducible factor 1a and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis
-
Peters CL, Morris CJ, Mapp PI, Blake DR, Lewis CE, Winrow VR: The transcription factors hypoxia-inducible factor 1a and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis. Arthritis Rheum (2004) 50(1):291-296.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.1
, pp. 291-296
-
-
Peters, C.L.1
Morris, C.J.2
Mapp, P.I.3
Blake, D.R.4
Lewis, C.E.5
Winrow, V.R.6
-
6
-
-
0023912369
-
The immunohistology of synovial lining cells in normal and inflamed synovium
-
Athanasou NA, Quinn J, Heryet A, Puddle B, Woods CG, McGee JO: The immunohistology of synovial lining cells in normal and inflamed synovium. J Pathol (1988) 155(2):133-142.
-
(1988)
J Pathol
, vol.155
, Issue.2
, pp. 133-142
-
-
Athanasou, N.A.1
Quinn, J.2
Heryet, A.3
Puddle, B.4
Woods, C.G.5
McGee, J.O.6
-
7
-
-
0021691606
-
Immune function in severe, active rheumatoid arthritis. A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and synovial tissue immunohistologic characteristics
-
Malone DG, Wahl SM, Tsokos M, Cattell H, Decker JL, Wilder RL: Immune function in severe, active rheumatoid arthritis. A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and synovial tissue immunohistologic characteristics. J Clin Invest (1984) 74(4):1173-1185.
-
(1984)
J Clin Invest
, vol.74
, Issue.4
, pp. 1173-1185
-
-
Malone, D.G.1
Wahl, S.M.2
Tsokos, M.3
Cattell, H.4
Decker, J.L.5
Wilder, R.L.6
-
8
-
-
0021932887
-
Bidirectional erosion of cartilage in the rheumatoid knee joint
-
Bromley M, Bertfield H, Evanson JM, Woolley DE: Bidirectional erosion of cartilage in the rheumatoid knee joint. Ann Rheum Dis (1985) 44(10):676-681.
-
(1985)
Ann Rheum Dis
, vol.44
, Issue.10
, pp. 676-681
-
-
Bromley, M.1
Bertfield, H.2
Evanson, J.M.3
Woolley, D.E.4
-
9
-
-
68149171810
-
Characterization of synovial tissue from arthritis patients: A proton magnetic resonance spectroscopic investigation
-
doi:10.1007/s00296-009-0865-z
-
Hitchon CA, El-Gabalawy HS, Bezabeh T: Characterization of synovial tissue from arthritis patients: A proton magnetic resonance spectroscopic investigation. Rheumatol Int (2009):doi:10.1007/s00296-009-0865-z.
-
(2009)
Rheumatol Int
-
-
Hitchon, C.A.1
El-Gabalawy, H.S.2
Bezabeh, T.3
-
10
-
-
34547555571
-
Angiogenesis inhibition as a therapeutic approach for inflammatory synovitis
-
Lainer-Carr D, Brahn E: Angiogenesis inhibition as a therapeutic approach for inflammatory synovitis. Nat Clin Pract Rheumatol (2007) 3(8):434-442.
-
(2007)
Nat Clin Pract Rheumatol
, vol.3
, Issue.8
, pp. 434-442
-
-
Lainer-Carr, D.1
Brahn, E.2
-
11
-
-
35348967491
-
Vasculopathy and disordered angiogenesis in selected rheumatic diseases: Rheumatoid arthritis and systemic sclerosis
-
Koch AE, Distler O: Vasculopathy and disordered angiogenesis in selected rheumatic diseases: Rheumatoid arthritis and systemic sclerosis. Arthritis Res Ther (2007) 9(Suppl 2):S3.
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.SUPPL. 2
-
-
Koch, A.E.1
Distler, O.2
-
12
-
-
0142011150
-
Angiogenic and angiostatic factors in the molecular control of angiogenesis
-
Distler JH, Hirth A, Kurowska-Stolarska M, Gay RE, Gay S, Distler O: Angiogenic and angiostatic factors in the molecular control of angiogenesis. Q J Nucl Med (2003) 47(3):149-161.
-
(2003)
Q J Nucl Med
, vol.47
, Issue.3
, pp. 149-161
-
-
Distler, J.H.1
Hirth, A.2
Kurowska-Stolarska, M.3
Gay, R.E.4
Gay, S.5
Distler, O.6
-
13
-
-
0028199835
-
Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis
-
Koch AE, Harlow LA, Haines GK, Amento EP, Unemori EN, Wong WL, Pope RM, Ferrara N: Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis. J Immunol (1994) 152(8):4149-4156.
-
(1994)
J Immunol
, vol.152
, Issue.8
, pp. 4149-4156
-
-
Koch, A.E.1
Harlow, L.A.2
Haines, G.K.3
Amento, E.P.4
Unemori, E.N.5
Wong, W.L.6
Pope, R.M.7
Ferrara, N.8
-
14
-
-
0033047875
-
VEGFs, receptors and angiogenesis
-
Veikkola T, Alitalo K: VEGFs, receptors and angiogenesis. Semin Cancer Biol (1999) 9(3):211-220.
-
(1999)
Semin Cancer Biol
, vol.9
, Issue.3
, pp. 211-220
-
-
Veikkola, T.1
Alitalo, K.2
-
15
-
-
0033841718
-
Expression of vascular endothelial growth factor isoforms and their receptors Flt-1, KDR, and neuropilin-1 in synovial tissues of rheumatoid arthritis
-
Ikeda M, Hosoda Y, Hirose S, Okada Y, Ikeda E: Expression of vascular endothelial growth factor isoforms and their receptors Flt-1, KDR, and neuropilin-1 in synovial tissues of rheumatoid arthritis. J Pathol (2000) 191(4):426-433.
-
(2000)
J Pathol
, vol.191
, Issue.4
, pp. 426-433
-
-
Ikeda, M.1
Hosoda, Y.2
Hirose, S.3
Okada, Y.4
Ikeda, E.5
-
16
-
-
0033043161
-
Peripheral blood mononuclear cells from patients with rheumatoid arthritis spontaneously secrete vascular endothelial growth factor (VEGF): Specific upregulation by tumor necrosis factor- (TNFα) in synovial fluid
-
Bottomley MJ, Webb NJ, Watson CJ, Holt PJ, Freemont AJ, Brenchley PE: Peripheral blood mononuclear cells from patients with rheumatoid arthritis spontaneously secrete vascular endothelial growth factor (VEGF): Specific upregulation by tumor necrosis factor- (TNFα) in synovial fluid. Clin Exp Immunol (1999) 117(1):171-176.
-
(1999)
Clin Exp Immunol
, vol.117
, Issue.1
, pp. 171-176
-
-
Bottomley, M.J.1
Webb, N.J.2
Watson, C.J.3
Holt, P.J.4
Freemont, A.J.5
Brenchley, P.E.6
-
17
-
-
0008362637
-
Hypoxia augments cytokine (transforming growth factor- (TGFβ) and IL-1)-induced vascular endothelial growth factor secretion by human synovial fibroblasts
-
Berse B, Hunt JA, Diegel RJ, Morganelli P, Yeo K, Brown F, Fava RA: Hypoxia augments cytokine (transforming growth factor- (TGFβ) and IL-1)-induced vascular endothelial growth factor secretion by human synovial fibroblasts. Clin Exp Immunol (1999) 115(1):176-182.
-
(1999)
Clin Exp Immunol
, vol.115
, Issue.1
, pp. 176-182
-
-
Berse, B.1
Hunt, J.A.2
Diegel, R.J.3
Morganelli, P.4
Yeo, K.5
Brown, F.6
Fava, R.A.7
-
18
-
-
0029944965
-
Dimerization, DNA binding, and transactivation properties of hypoxia- inducible factor 1
-
Jiang BH, Rue E, Wang GL, Roe R, Semenza GL: Dimerization, DNA binding, and transactivation properties of hypoxia- inducible factor 1. J Biol Chem (1996) 271(30):17771-17778.
-
(1996)
J Biol Chem
, vol.271
, Issue.30
, pp. 17771-17778
-
-
Jiang, B.H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
19
-
-
18444364209
-
Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1
-
Liu LX, Lu H, Luo Y, Date T, Belanger AJ, Vincent KA, Akita GY, Goldberg M, Cheng SH, Gregory RJ, Jiang C: Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1. Biochem Biophys Res Commun (2002) 291(4):908-914.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, Issue.4
, pp. 908-914
-
-
Liu, L.X.1
Lu, H.2
Luo, Y.3
Date, T.4
Belanger, A.J.5
Vincent, K.A.6
Akita, G.Y.7
Goldberg, M.8
Cheng, S.H.9
Gregory, R.J.10
Jiang, C.11
-
20
-
-
0242335590
-
Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis
-
Giatromanolaki A, Sivridis E, Maltezos E, Athanassou N, Papazoglou D, Gatter KC, Harris AL, Koukourakis MI: Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis. Arthritis Res Ther (2003) 5(4):R193-R201.
-
(2003)
Arthritis Res Ther
, vol.5
, Issue.4
-
-
Giatromanolaki, A.1
Sivridis, E.2
Maltezos, E.3
Athanassou, N.4
Papazoglou, D.5
Gatter, K.C.6
Harris, A.L.7
Koukourakis, M.I.8
-
21
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for TIE2 that disrupts in vivo angiogenesis
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ et al: Angiopoietin-2, a natural antagonist for TIE2 that disrupts in vivo angiogenesis. Science (1997) 277(5322): 55-60.
-
(1997)
Science
, vol.277
, Issue.5322
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
-
22
-
-
0036237242
-
Differential expression of the angiogenic TIE receptor family in arthritic and normal synovial tissue
-
Shahrara S, Volin MV, Connors MA, Haines GK, Koch AE: Differential expression of the angiogenic TIE receptor family in arthritic and normal synovial tissue. Arthritis Res (2002) 4(3):201-208.
-
(2002)
Arthritis Res
, vol.4
, Issue.3
, pp. 201-208
-
-
Shahrara, S.1
Volin, M.V.2
Connors, M.A.3
Haines, G.K.4
Koch, A.E.5
-
23
-
-
35248867961
-
Activation of the orphan endothelial receptor TIE1 modifies TIE2-mediated intracellular signaling and cell survival
-
Yuan HT, Venkatesha S, Chan B, Deutsch U, Mammoto T, Sukhatme VP, Woolf AS, Karumanchi SA: Activation of the orphan endothelial receptor TIE1 modifies TIE2-mediated intracellular signaling and cell survival. FASEB J (2007) 21(12):3171-3183.
-
(2007)
FASEB J
, vol.21
, Issue.12
, pp. 3171-3183
-
-
Yuan, H.T.1
Venkatesha, S.2
Chan, B.3
Deutsch, U.4
Mammoto, T.5
Sukhatme, V.P.6
Woolf, A.S.7
Karumanchi, S.A.8
-
24
-
-
0027862597
-
Taxol: A history of pharmaceutical development and current pharmaceutical concerns
-
Adams JD, Flora KP, Goldspiel BR, Wilson JW, Arbuck SG, Finley R: Taxol: A history of pharmaceutical development and current pharmaceutical concerns. J Natl Cancer Inst Monogr (1993) (15):141-147.
-
(1993)
J Natl Cancer Inst Monogr
, vol.15
, pp. 141-147
-
-
Adams, J.D.1
Flora, K.P.2
Goldspiel, B.R.3
Wilson, J.W.4
Arbuck, S.G.5
Finley, R.6
-
25
-
-
0032566338
-
Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes
-
Kielbassa K, Schmitz C, Gerke V: Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes. Exp Cell Res (1998) 243(1):129-141.
-
(1998)
Exp Cell Res
, vol.243
, Issue.1
, pp. 129-141
-
-
Kielbassa, K.1
Schmitz, C.2
Gerke, V.3
-
26
-
-
0030924753
-
The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
-
Sin N, Meng L, Wang MQ, Wen JJ, Bornmann WG, Crews CM: The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc Natl Acad Sci USA (1997) 94(12):6099-6103.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.12
, pp. 6099-6103
-
-
Sin, N.1
Meng, L.2
Wang, M.Q.3
Wen, J.J.4
Bornmann, W.G.5
Crews, C.M.6
-
27
-
-
0027536332
-
Adhesion molecule expression in human synovial tissue
-
Johnson BA, Haines GK, Harlow LA, Koch AE: Adhesion molecule expression in human synovial tissue. Arthritis Rheum (1993) 36(2):137-146.
-
(1993)
Arthritis Rheum
, vol.36
, Issue.2
, pp. 137-146
-
-
Johnson, B.A.1
Haines, G.K.2
Harlow, L.A.3
Koch, A.E.4
-
28
-
-
0028670833
-
3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell (1994) 79(7):1157-1164.
-
(1994)
Cell
, vol.79
, Issue.7
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
Reisfeld, R.A.4
Hu, T.5
Klier, G.6
Cheresh, D.A.7
-
30
-
-
60149085396
-
The many roles of Fas receptor signaling in the immune system
-
Strasser A, Jost PJ, Nagata S: The many roles of Fas receptor signaling in the immune system. Immunity (2009) 30(2):180-192.
-
(2009)
Immunity
, vol.30
, Issue.2
, pp. 180-192
-
-
Strasser, A.1
Jost, P.J.2
Nagata, S.3
-
31
-
-
34249026695
-
Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis
-
Kim WU, Kwok SK, Hong KH, Yoo SA, Kong JS, Choe J, Cho CS: Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis. Arthritis Res Ther (2007) 9(2):R42.
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.2
-
-
Kim, W.U.1
Kwok, S.K.2
Hong, K.H.3
Yoo, S.A.4
Kong, J.S.5
Choe, J.6
Cho, C.S.7
-
32
-
-
0037143764
-
VEGF-Trap: A VEGF blocker with potent antitumor effects
-
Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E et al: VEGF-Trap: A VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA (2002) 99(17):11393-11398.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.17
, pp. 11393-11398
-
-
Holash, J.1
Davis, S.2
Papadopoulos, N.3
Croll, S.D.4
Ho, L.5
Russell, M.6
Boland, P.7
Leidich, R.8
Hylton, D.9
Burova, E.10
Ioffe, E.11
-
33
-
-
0032493654
-
165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
-
165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J Biol Chem (1998) 273(32):20556-20567.
-
(1998)
J Biol Chem
, vol.273
, Issue.32
, pp. 20556-20567
-
-
Ruckman, J.1
Green, L.S.2
Beeson, J.3
Waugh, S.4
Gillette, W.L.5
Henninger, D.D.6
Claesson-Welsh, L.7
Janjic, N.8
-
34
-
-
1942453816
-
Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK-787/ZK-222584, causes significant anti-arthritic effects in models of rheumatoid arthritis
-
Grosios K, Wood J, Esser R, Raychaudhuri A, Dawson J: Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK-787/ZK-222584, causes significant anti-arthritic effects in models of rheumatoid arthritis. Inflamm Res (2004) 53(4):133-142.
-
(2004)
Inflamm Res
, vol.53
, Issue.4
, pp. 133-142
-
-
Grosios, K.1
Wood, J.2
Esser, R.3
Raychaudhuri, A.4
Dawson, J.5
-
35
-
-
10744228170
-
Blockade of vascular endothelial growth factor receptor I (VEGFR-I), but not VEGFR-II, suppresses joint destruction in the K/BxN model of rheumatoid arthritis
-
De Bandt M, Ben Mahdi MH, Ollivier V, Grossin M, Dupuis M, Gaudry M, Bohlen P, Lipson KE, Rice A, Wu Y, Gougerot-Pocidalo MA, Pasquier C: Blockade of vascular endothelial growth factor receptor I (VEGFR-I), but not VEGFR-II, suppresses joint destruction in the K/BxN model of rheumatoid arthritis. J Immunol (2003) 171(9):4853-4859.
-
(2003)
J Immunol
, vol.171
, Issue.9
, pp. 4853-4859
-
-
De Bandt, M.1
Ben Mahdi, M.H.2
Ollivier, V.3
Grossin, M.4
Dupuis, M.5
Gaudry, M.6
Bohlen, P.7
Lipson, K.E.8
Rice, A.9
Wu, Y.10
Gougerot-Pocidalo, M.A.11
Pasquier, C.12
-
36
-
-
39449096999
-
Prophylactic but not therapeutic activity of a monoclonal antibody that neutralizes the binding of VEGFB to VEGFR1 in a murine collagen-induced arthritis model
-
Mould AW, Scotney P, Greco SA, Hayward NK, Nash A, Kay GF: Prophylactic but not therapeutic activity of a monoclonal antibody that neutralizes the binding of VEGFB to VEGFR1 in a murine collagen-induced arthritis model. Rheumatology (Oxford) (2008) 47(3):263-266.
-
(2008)
Rheumatology (Oxford)
, vol.47
, Issue.3
, pp. 263-266
-
-
Mould, A.W.1
Scotney, P.2
Greco, S.A.3
Hayward, N.K.4
Nash, A.5
Kay, G.F.6
-
37
-
-
48249150751
-
Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis
-
Jin P, Zhang J, Sumariwalla PF, Ni I, Jorgensen B, Crawford D, Phillips S, Feldmann M, Shepard HM, Paleolog EM: Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis. Arthritis Res Ther (2008) 10(4):R73.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.4
-
-
Jin, P.1
Zhang, J.2
Sumariwalla, P.F.3
Ni, I.4
Jorgensen, B.5
Crawford, D.6
Phillips, S.7
Feldmann, M.8
Shepard, H.M.9
Paleolog, E.M.10
-
38
-
-
0042261694
-
Antitumor efficacy of FK-228, a novel histone deacetylase inhibitor, depends on the effect on expression of angiogenesis factors
-
Sasakawa Y, Naoe Y, Noto T, Inoue T, Sasakawa T, Matsuo M, Manda T, Mutoh S: Antitumor efficacy of FK-228, a novel histone deacetylase inhibitor, depends on the effect on expression of angiogenesis factors. Biochem Pharmacol (2003) 66(6):897-906.
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.6
, pp. 897-906
-
-
Sasakawa, Y.1
Naoe, Y.2
Noto, T.3
Inoue, T.4
Sasakawa, T.5
Matsuo, M.6
Manda, T.7
Mutoh, S.8
-
39
-
-
38349104030
-
Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts
-
Manabe H, Nasu Y, Komiyama T, Furumatsu T, Kitamura A, Miyazawa S, Ninomiya Y, Ozaki T, Asahara H, Nishida K: Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts. Inflamm Res (2008) 57(1):4-10.
-
(2008)
Inflamm Res
, vol.57
, Issue.1
, pp. 4-10
-
-
Manabe, H.1
Nasu, Y.2
Komiyama, T.3
Furumatsu, T.4
Kitamura, A.5
Miyazawa, S.6
Ninomiya, Y.7
Ozaki, T.8
Asahara, H.9
Nishida, K.10
-
40
-
-
18644372654
-
Gene therapy targeting the TIE2 function ameliorates collagen-induced arthritis and protects against bone destruction
-
Chen Y, Donnelly E, Kobayashi H, Debusk LM, Lin PC: Gene therapy targeting the TIE2 function ameliorates collagen-induced arthritis and protects against bone destruction. Arthritis Rheum (2005) 52(5):1585- 1594.
-
(2005)
Arthritis Rheum
, vol.52
, Issue.5
, pp. 1585-1594
-
-
Chen, Y.1
Donnelly, E.2
Kobayashi, H.3
Debusk, L.M.4
Lin, P.C.5
-
41
-
-
41149126578
-
Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: An effect independent of an anti-angiogenic action
-
Issekutz AC, Sapru K: Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: An effect independent of an anti-angiogenic action. Int Immunopharmacol (2008) 8(5):708-716.
-
(2008)
Int Immunopharmacol
, vol.8
, Issue.5
, pp. 708-716
-
-
Issekutz, A.C.1
Sapru, K.2
-
42
-
-
56449110050
-
An angiogenesis inhibitor, 2-methoxyestradiol, involutes rat collagen-induced arthritis and suppresses gene expression of synovial vascular endothelial growth factor and basic fibroblast growth factor
-
Brahn E, Banquerigo ML, Lee JK, Park EJ, Fogler WE, Plum SM: An angiogenesis inhibitor, 2-methoxyestradiol, involutes rat collagen-induced arthritis and suppresses gene expression of synovial vascular endothelial growth factor and basic fibroblast growth factor. J Rheumatol (2008) 35(11):2119-2128.
-
(2008)
J Rheumatol
, vol.35
, Issue.11
, pp. 2119-2128
-
-
Brahn, E.1
Banquerigo, M.L.2
Lee, J.K.3
Park, E.J.4
Fogler, W.E.5
Plum, S.M.6
-
43
-
-
46749144280
-
-
EntreMed Inc: EntreMed Focuses on development of ENMD-2076, December 15
-
EntreMed Inc: EntreMed Focuses on development of ENMD-2076. Press Release (2008): December 15.
-
(2008)
Press Release
-
-
-
44
-
-
0035433163
-
Effects of paclitaxel on cultured synovial cells from patients with rheumatoid arthritis
-
Kurose A, Yoshida W, Yoshida M, Sawai T: Effects of paclitaxel on cultured synovial cells from patients with rheumatoid arthritis. Cytometry (2001) 44(4):349-354.
-
(2001)
Cytometry
, vol.44
, Issue.4
, pp. 349-354
-
-
Kurose, A.1
Yoshida, W.2
Yoshida, M.3
Sawai, T.4
-
45
-
-
0028335937
-
Regression of collagen-induced arthritis with taxol, a microtubule stabilizer
-
Brahn E, Tang C, Banquerigo ML: Regression of collagen-induced arthritis with taxol, a microtubule stabilizer. Arthritis Rheum (1994) 37(6):839-845.
-
(1994)
Arthritis Rheum
, vol.37
, Issue.6
, pp. 839-845
-
-
Brahn, E.1
Tang, C.2
Banquerigo, M.L.3
-
46
-
-
0028088225
-
Suppression of collagen- induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol
-
Oliver SJ, Banquerigo ML, Brahn E: Suppression of collagen- induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol. Cell Immunol (1994) 157(1):291-299.
-
(1994)
Cell Immunol
, vol.157
, Issue.1
, pp. 291-299
-
-
Oliver, S.J.1
Banquerigo, M.L.2
Brahn, E.3
-
47
-
-
4344579795
-
Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: Biocompatibility and efficacy determinations in rabbits
-
Liggins RT, Cruz T, Min W, Liang L, Hunter WL, Burt HM: Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: Biocompatibility and efficacy determinations in rabbits. Inflamm Res (2004) 53(8):363-372.
-
(2004)
Inflamm Res
, vol.53
, Issue.8
, pp. 363-372
-
-
Liggins, R.T.1
Cruz, T.2
Min, W.3
Liang, L.4
Hunter, W.L.5
Burt, H.M.6
-
48
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J: Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell (1997) 88(2):277-285.
-
(1997)
Cell
, vol.88
, Issue.2
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
Fukai, N.4
Vasios, G.5
Lane, W.S.6
Flynn, E.7
Birkhead, J.R.8
Olsen, B.R.9
Folkman, J.10
-
49
-
-
0026582030
-
Suppression of collagen arthritis with antibodies to an arthritogenic, oligoclonal T-cell line
-
Peacock DJ, Ku G, Banquerigo ML, Brahn E: Suppression of collagen arthritis with antibodies to an arthritogenic, oligoclonal T-cell line. Cell Immunol (1992) 140(2):444-452.
-
(1992)
Cell Immunol
, vol.140
, Issue.2
, pp. 444-452
-
-
Peacock, D.J.1
Ku, G.2
Banquerigo, M.L.3
Brahn, E.4
-
50
-
-
0026549481
-
Angiogenesis inhibition suppresses collagen arthritis
-
Peacock DJ, Banquerigo ML, Brahn E: Angiogenesis inhibition suppresses collagen arthritis. J Exp Med (1992) 175(4):1135-1138.
-
(1992)
J Exp Med
, vol.175
, Issue.4
, pp. 1135-1138
-
-
Peacock, D.J.1
Banquerigo, M.L.2
Brahn, E.3
-
51
-
-
0034901968
-
Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer
-
Logothetis CJ, Wu KK, Finn LD, Daliani D, Figg W, Ghaddar H, Gutterman JU: Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer. Clin Cancer Res (2001) 7(5):1198-1203.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.5
, pp. 1198-1203
-
-
Logothetis, C.J.1
Wu, K.K.2
Finn, L.D.3
Daliani, D.4
Figg, W.5
Ghaddar, H.6
Gutterman, J.U.7
-
52
-
-
0033711671
-
Suppression of arthritis and protection from bone destruction by treatment with TNP-470/AGM-1470 in a transgenic mouse model of rheumatoid arthritis
-
de Bandt M, Grossin M, Weber AJ, Chopin M, Elbim C, Pla M, Gougerot-Pocidalo MA, Gaudry M: Suppression of arthritis and protection from bone destruction by treatment with TNP-470/AGM-1470 in a transgenic mouse model of rheumatoid arthritis. Arthritis Rheum (2000) 43(9):2056- 2063.
-
(2000)
Arthritis Rheum
, vol.43
, Issue.9
, pp. 2056-2063
-
-
de Bandt, M.1
Grossin, M.2
Weber, A.J.3
Chopin, M.4
Elbim, C.5
Pla, M.6
Gougerot-Pocidalo, M.A.7
Gaudry, M.8
-
53
-
-
67649324060
-
-
Takeda Chemical Industries Ltd: Financial results for FY2001, Data book, March 28
-
Takeda Chemical Industries Ltd: Financial results for FY2001 - Data book. Company Communication (2002): March 28.
-
(2002)
Company Communication
-
-
-
54
-
-
38149058256
-
Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: Potential role for angiogenesis inhibition
-
Bainbridge J, Madden L, Essex D, Binks M, Malhotra R, Paleolog EM: Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: Potential role for angiogenesis inhibition. Arthritis Res Ther (2007) 9(6):R127.
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.6
-
-
Bainbridge, J.1
Madden, L.2
Essex, D.3
Binks, M.4
Malhotra, R.5
Paleolog, E.M.6
-
55
-
-
38349105957
-
An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis
-
Lazarus DD, Doyle EG, Bernier SG, Rogers AB, Labenski MT, Wakefield JD, Karp RM, Clark EJ, Lorusso J, Hoyt JG, Thompson CD et al: An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis. Inflamm Res (2008) 57(1):18-27.
-
(2008)
Inflamm Res
, vol.57
, Issue.1
, pp. 18-27
-
-
Lazarus, D.D.1
Doyle, E.G.2
Bernier, S.G.3
Rogers, A.B.4
Labenski, M.T.5
Wakefield, J.D.6
Karp, R.M.7
Clark, E.J.8
Lorusso, J.9
Hoyt, J.G.10
Thompson, C.D.11
-
56
-
-
0033121275
-
v integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
-
v integrins during angiogenesis: Insights into potential mechanisms of action and clinical development. J Clin Invest (1999) 103(9):1227-1230.
-
(1999)
J Clin Invest
, vol.103
, Issue.9
, pp. 1227-1230
-
-
Eliceiri, B.P.1
Cheresh, D.A.2
-
57
-
-
0035150588
-
3(vitronectin receptor) antagonist, in rat adjuvant-induced arthritis
-
3(vitronectin receptor) antagonist, in rat adjuvant-induced arthritis. Arthritis Rheum (2001) 44(1):128-137.
-
(2001)
Arthritis Rheum
, vol.44
, Issue.1
, pp. 128-137
-
-
Badger, A.M.1
Blake, S.2
Kapadia, R.3
Sarkar, S.4
Levin, J.5
Swift, B.A.6
Hoffman, S.J.7
Stroup, G.B.8
Miller, W.H.9
Gowen, M.10
Lark, M.W.11
-
59
-
-
67649356334
-
AstraZeneca development pipeline: 7 December 2007
-
December 07
-
AstraZeneca plc: AstraZeneca development pipeline: 7 December 2007. Company World Wide Web site (2007): December 07.
-
(2007)
Company World Wide Web site
-
-
AstraZeneca plc1
-
60
-
-
0038546771
-
Inhibition of arthritis by systemic administration of endostatin in passive murine collagen-induced arthritis
-
Kurosaka D, Yoshida K, Yasuda J, Yokoyama T, Kingetsu I, Yamaguchi N, Joh K, Matsushima M, Saito S, Yamada A: Inhibition of arthritis by systemic administration of endostatin in passive murine collagen-induced arthritis. Ann Rheum Dis (2003) 62(7):677-679.
-
(2003)
Ann Rheum Dis
, vol.62
, Issue.7
, pp. 677-679
-
-
Kurosaka, D.1
Yoshida, K.2
Yasuda, J.3
Yokoyama, T.4
Kingetsu, I.5
Yamaguchi, N.6
Joh, K.7
Matsushima, M.8
Saito, S.9
Yamada, A.10
-
61
-
-
0036257310
-
Treatment with the angiogenesis inhibitor endostatin: A novel therapy in rheumatoid arthritis
-
Matsuno H, Yudoh K, Uzuki M, Nakazawa F, Sawai T, Yamaguchi N, Olsen BR, Kimura T: Treatment with the angiogenesis inhibitor endostatin: A novel therapy in rheumatoid arthritis. J Rheumatol (2002) 29(5):890-895.
-
(2002)
J Rheumatol
, vol.29
, Issue.5
, pp. 890-895
-
-
Matsuno, H.1
Yudoh, K.2
Uzuki, M.3
Nakazawa, F.4
Sawai, T.5
Yamaguchi, N.6
Olsen, B.R.7
Kimura, T.8
-
62
-
-
4544253379
-
Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflammatory factors
-
Yue L, Wang H, Liu LH, Shen YX, Wei W: Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflammatory factors. Acta Pharmacol Sin (2004) 25(9):1182-1185.
-
(2004)
Acta Pharmacol Sin
, vol.25
, Issue.9
, pp. 1182-1185
-
-
Yue, L.1
Wang, H.2
Liu, L.H.3
Shen, Y.X.4
Wei, W.5
-
63
-
-
37349083808
-
The effect of endostatin evaluated in an experimental animal model of collagen-induced arthritis
-
Kurosaka D, Yoshida K, Yasuda J, Yasuda C, Noda K, Furuya K, Ukichi T, Kingetsu I, Joh K, Yamaguchi N, Saito S, Yamada A:The effect of endostatin evaluated in an experimental animal model of collagen-induced arthritis. Scand J Rheumatol (2007) 36(6):434-441.
-
(2007)
Scand J Rheumatol
, vol.36
, Issue.6
, pp. 434-441
-
-
Kurosaka, D.1
Yoshida, K.2
Yasuda, J.3
Yasuda, C.4
Noda, K.5
Furuya, K.6
Ukichi, T.7
Kingetsu, I.8
Joh, K.9
Yamaguchi, N.10
Saito, S.11
Yamada, A.12
-
64
-
-
34249031196
-
Blockage of the formation of new blood vessels by recombinant human endostatin contributes to the regression of rat adjuvant arthritis
-
Yue L, Shen YX, Feng LJ, Chen FH, Yao HW, Liu LH, Wu Q, Wang H: Blockage of the formation of new blood vessels by recombinant human endostatin contributes to the regression of rat adjuvant arthritis. Eur J Pharmacol (2007) 567(1-2): 166-170.
-
(2007)
Eur J Pharmacol
, vol.567
, Issue.1-2
, pp. 166-170
-
-
Yue, L.1
Shen, Y.X.2
Feng, L.J.3
Chen, F.H.4
Yao, H.W.5
Liu, L.H.6
Wu, Q.7
Wang, H.8
-
65
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J: Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell (1994) 79(2):315-328.
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 315-328
-
-
O'Reilly, M.S.1
Holmgren, L.2
Shing, Y.3
Chen, C.4
Rosenthal, R.A.5
Moses, M.6
Lane, W.S.7
Cao, Y.8
Sage, E.H.9
Folkman, J.10
-
66
-
-
0036188225
-
Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis
-
Kim JM, Ho SH, Park EJ, Hahn W, Cho H, Jeong JG, Lee YW, Kim S: Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis. Arthritis Rheum (2002) 46(3):793-801.
-
(2002)
Arthritis Rheum
, vol.46
, Issue.3
, pp. 793-801
-
-
Kim, J.M.1
Ho, S.H.2
Park, E.J.3
Hahn, W.4
Cho, H.5
Jeong, J.G.6
Lee, Y.W.7
Kim, S.8
-
67
-
-
26844498412
-
Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice
-
Takahashi H, Kato K, Miyake K, Hirai Y, Yoshino S, Shimada T: Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice. Clin Exp Rheumatol (2005) 23(4):455-461.
-
(2005)
Clin Exp Rheumatol
, vol.23
, Issue.4
, pp. 455-461
-
-
Takahashi, H.1
Kato, K.2
Miyake, K.3
Hirai, Y.4
Yoshino, S.5
Shimada, T.6
-
68
-
-
25144487618
-
Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice
-
Kato K, Miyake K, Igarashi T, Yoshino S, Shimada T: Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice. Rheumatol Int (2005) 25(7):522-529.
-
(2005)
Rheumatol Int
, vol.25
, Issue.7
, pp. 522-529
-
-
Kato, K.1
Miyake, K.2
Igarashi, T.3
Yoshino, S.4
Shimada, T.5
-
69
-
-
0025260038
-
Myxoma virus and malignant rabbit fibroma virus encode a serpin-like protein important for virus virulence
-
Upton C, Macen JL, Wishart DS, McFadden G: Myxoma virus and malignant rabbit fibroma virus encode a serpin-like protein important for virus virulence. Virology (1990) 179(2):618-631.
-
(1990)
Virology
, vol.179
, Issue.2
, pp. 618-631
-
-
Upton, C.1
Macen, J.L.2
Wishart, D.S.3
McFadden, G.4
-
70
-
-
0029891529
-
Amelioration of antigen-induced arthritis in rabbits treated with a secreted viral serine proteinase inhibitor
-
Maksymowych WP, Nation N, Nash P, Macen J, Lucas A, McFadden G, Russell AS: Amelioration of antigen-induced arthritis in rabbits treated with a secreted viral serine proteinase inhibitor. J Rheumatol (1996) 23(5):878-882.
-
(1996)
J Rheumatol
, vol.23
, Issue.5
, pp. 878-882
-
-
Maksymowych, W.P.1
Nation, N.2
Nash, P.3
Macen, J.4
Lucas, A.5
McFadden, G.6
Russell, A.S.7
-
71
-
-
34447281264
-
Viral serpin, Serp-1, inhibits endogenous angiogenesis in the chicken chorioallantoic membrane model
-
Richardson M, Liu L, Dunphy L, Wong D, Sun Y, Viswanathan K, Singh G, Lucas A: Viral serpin, Serp-1, inhibits endogenous angiogenesis in the chicken chorioallantoic membrane model. Cardiovasc Pathol (2007) 16(4):191-202.
-
(2007)
Cardiovasc Pathol
, vol.16
, Issue.4
, pp. 191-202
-
-
Richardson, M.1
Liu, L.2
Dunphy, L.3
Wong, D.4
Sun, Y.5
Viswanathan, K.6
Singh, G.7
Lucas, A.8
-
73
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato RJ, Loughnan MS, Flynn E, Folkman J: Thalidomide is an inhibitor of angiogenesis. Proc Natl Acad Sci USA (1994) 91(9):4082-4085.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.9
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
74
-
-
0030904683
-
Thalidomide therapy of established collagen-induced arthritis (CIA) not accompanied by an evident Th2 shift
-
Hauschild A, Kroeger H, Mitchison NA, Ugrinovic S, Zwingenberger K: Thalidomide therapy of established collagen-induced arthritis (CIA) not accompanied by an evident Th2 shift. Clin Exp Immunol (1997) 108(3):428-431.
-
(1997)
Clin Exp Immunol
, vol.108
, Issue.3
, pp. 428-431
-
-
Hauschild, A.1
Kroeger, H.2
Mitchison, N.A.3
Ugrinovic, S.4
Zwingenberger, K.5
-
75
-
-
0031921590
-
The effect of thalidomide and 2 analogs on collagen-induced arthritis
-
Oliver SJ, Cheng TP, Banquerigo ML, Brahn E: The effect of thalidomide and 2 analogs on collagen-induced arthritis. J Rheumatol (1998) 25(5):964-969.
-
(1998)
J Rheumatol
, vol.25
, Issue.5
, pp. 964-969
-
-
Oliver, S.J.1
Cheng, T.P.2
Banquerigo, M.L.3
Brahn, E.4
-
76
-
-
0029801341
-
An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis
-
Huizinga TW, Dijkmans BA, van der Velde EA, van de Pouw Kraan TC, Verweij CL, Breedveld FC: An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis. Ann Rheum Dis (1996) 55(11):833-836.
-
(1996)
Ann Rheum Dis
, vol.55
, Issue.11
, pp. 833-836
-
-
Huizinga, T.W.1
Dijkmans, B.A.2
van der Velde, E.A.3
van de Pouw Kraan, T.C.4
Verweij, C.L.5
Breedveld, F.C.6
|