Synthesis of 4-substituted pyrido[2,3-d]pyrimidin-4(1H)-one as analgesic and anti-inflammatory agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 13, 2009, Pages 3392-3397

  El Gazzar, Abdel Rahman B A ^a   Hafez, Hend N ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Analgesic activity; Anti inflammatory; Pyrido 2,3 d pyrimidines; Ulcerogenicity

Indexed keywords

5 [4 (4 METHYLPIPERAZINYL)PHENYL] 2 THIOXOPYRIDO[2,3 D]PYRIMIDINE; 5 [4 (4 MORPHOLINYL)PHENYL] 2 THIOXOPYRIDO [2,3 D]PYRIMIDINE; 6 AMINOTHIOURACIL; ACETIC ACID; ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; CARBON DISULFIDE; DICLOFENAC; DIHYDROPYRIDO[2,3 D]PYRIMIDIN 4(1H) ONE DERIVATIVE; FORMAMIDE; FORMIC ACID; MALONONITRILE; PYRIDO[2,3 D]PYRIMIDIN 4(1H) ONE DERIVATIVE; THIOUREA; UNCLASSIFIED DRUG; UREA;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG SYNTHESIS; NONHUMAN; OXIDATION; PAW EDEMA; RAT; SUBSTITUTION REACTION; ULCER;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FEMALE; MALE; PIPERIDINES; PYRIMIDINES; PYRIMIDINONES; RATS; RATS, WISTAR;

EID: 67649160744     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.044     Document Type: Article

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