Synthesis and structure-activity relationships of 5-heteroatom-substituted pyridopyrimidines as adenosine kinase inhibitors

European Journal of Medicinal Chemistry

Volumn 38, Issue 3, 2003, Pages 245-252

  Gfesser, Gregory A ^a,b   Bayburt, Erol K ^a   Cowart, Marlon ^a   DiDomenico, Stanley ^a   Gomtsyan, Arthur ^a   Lee, Chih Hung ^a   Stewart, Andrew O ^a   Jarvis, Michael F ^a   Kowaluk, Elizabeth A ^a   Bhagwat, Shripad S ^b  

^a ABBOTT LABORATORIES   (United States)

^b CELGENE CORPORATION   (United States)

Author keywords

Adenosine; Hyperalgesia; Pyridopyrimidines

Indexed keywords

ADENOSINE KINASE INHIBITOR; PYRIDOPYRIMIDINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SOLUBILITY; DRUG SYNTHESIS; ENZYME INHIBITION; HYPERALGESIA; STRUCTURE ACTIVITY RELATION;

EID: 0037343929     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(03)00019-9     Document Type: Article

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