Hsp90β and p130cas: Novel regulatory factors of MMP-13 expression in human osteoarthritic chondrocytes

Annals of the Rheumatic Diseases

Volumn 68, Issue 6, 2009, Pages 976-982

  Fan, Z ^a   Tardif, G ^a   Hum, D ^a   Duval, N ^b   Pelletier, J P ^a   Martel Pelletier, J ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b Pavillon des Charmilles ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; CRK ASSOCIATED SUBSTRATE PROTEIN; GELATINASE A; GELATINASE B; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90BETA; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE 14; SMALL INTERFERING RNA; STROMELYSIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CARTILAGE CELL; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 67449159238     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2008.092288     Document Type: Article

References (35)

1. Fosang AJ, Last K, Knauper V, Murphy G, Neame PJ. Degradation of cartilage aggrecan by collagenase-3 (MMP-13). FEBS Lett 1996;380:17-20. (Pubitemid 26058726)
2. Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: a role in osteoarthritis. J Clin Invest 1996;97:2011-2019 (Pubitemid 26143954)
3. Knauper V, Cowell S, Smith B, Lopez-Otin C, O'Shea M, Morris H, et al. The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction. J Biol Chem 1997;272:7608-7616 (Pubitemid 27137308)
4. Hiller O, Lichte A, Oberpichler A, Kocourek A, Tschesche H. Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase impair clotting by degradation of fibrinogen and factor XII. J Biol Chem 2000;275:33008-33013 (Pubitemid 30797081)
5. Hashimoto G, Inoki I, Fujii Y, Aoki T, Ikeda E, Okada Y. Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165. J Biol Chem 2002;277:36288-36295
6. Monfort J, Tardif G, Reboul P, Mineau F, Roughley P, Pelletier JP, et al. Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site. Arthritis Res Ther 2006;8:R26.
7. Monfort J, Tardif G, Roughley P, Reboul P, Boileau C, Bishop PN, et al. Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: a novel target for MMP-13 in osteoarthritis. Osteoarthritis Cartilage 2007;16:749-755
8. Tardif G, Reboul P, Dupuis M, Changshan G, Duval N, Pelletier JP, et al. TGF-betainduced collagenase-3 production in human osteoarthritic chondrocytes is triggered by SMAD proteins: cooperation between AP-1 and PEA-3 binding sites. J Rheumatol 2001;28:1631-1639
9. Benderdour M, Tardif G, Pelletier J, Di Battista JA, Reboul P, Ranger P, et al. Interleukin-17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via an AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1β. J Rheumatol 2002;29:1262-1272 (Pubitemid 34601964)
10. Forsyth CB, Pulai J, Loeser RF. Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes. Arthritis Rheum 2002;46:2368-2376
11. Guevremont M, Martel-Pelletier J, Massicotte F, Tardif G, Pelletier JP, Ranger P, et al. Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HgF: potential implication of osteoblasts on the presence of HGF in cartilage. J Bone Miner Res 2003;18:1073-1081 (Pubitemid 37294945)
12. Loeser RF, Forsyth CB, Samarel AM, Im HJ. Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway. J Biol Chem 2003;278:24577-24585 (Pubitemid 37548610)
13. Yokota H, Goldring MB, Sun HB. CITED2-mediated regulation of MMP-1 and MMP- 13 in human chondrocytes under flow shear. J Biol Chem 2003;278:47275-47280 (Pubitemid 37452316)
14. Hall DA, Zhu H, Zhu X, Royce T, Gerstein M, Snyder M. Regulation of gene expression by a metabolic enzyme. Science 2004;306:482-484 (Pubitemid 39372447)
15. Scheer U, Hinssen H, Franke WW, Jockusch BM. Microinjection of actin-binding proteins and actin antibodies demonstrates involvement of nuclear actin in transcription of lampbrush chromosomes. Cell 1984;39:111-122 (Pubitemid 15218230)
16. Hofmann WA, Stojiljkovic L, Fuchsova B, Vargas GM, Mavrommatis E, Philimonenko V, et al. Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II. Nat Cell Biol 2004;6:1094-1101 (Pubitemid 39468010)
17. Grummt I. Actin and myosin as transcription factors. Curr Opin Genet Dev 2006;16:191-196 (Pubitemid 43376067)
18. Freeman BC, Yamamoto KR. Disassembly of transcriptional regulatory complexes by molecular chaperones. Science 2002;296:2232-2235 (Pubitemid 34680310)
19. Tardif G, Pelletier JP, Dupuis M, Geng C, Cloutier JM, Martel-Pelletier J. Collagenase 3 production by human osteoarthritic chondrocytes in response to growth factors and cytokines is a function of the physiological state of the cells. Arthritis Rheum 1999;42:1147-1158 (Pubitemid 29268951)
20. Fan Z, Tardif G, Boileau C, Bidwell JP, Geng C, Hum D, et al. Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter. Arthritis Rheum 2006;54:2471-2480 (Pubitemid 44205007)
21. Altman RD, Asch E, Bloch DA, Bole G, Borenstein D, Brandt KD, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Arthritis Rheum 1986;29:1039-1049
22. Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971;53:523-537
23. Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum 2004;50:2521-2530 (Pubitemid 39062713)
24. Benderdour M, Tardif G, Pelletier JP, Dupuis M, Geng C, Martel-Pelletier J. A novel negative regulatory element in the human collagenase-3 proximal promoter region. Biochem Biophys Res Commun 2002;291:1151-1159 (Pubitemid 34694310)
25. Helmbrecht K, Zeise E, Rensing L. Chaperones in cell cycle regulation and mitogenic signal transduction: a review. Cell Prolif 2000;33:341-365 (Pubitemid 30943353)
26. Richter K, Buchner J. Hsp90: chaperoning signal transduction. J Cell Physiol 2001;188:281-290 (Pubitemid 32777169)
27. Zhang H, Burrows F. Targeting multiple signal transduction pathways through inhibition of Hsp90. J Mol Med 2004;82:488-499 (Pubitemid 39149859)
28. O'Neill GM, Fashena SJ, Golemis EA. Integrin signalling: a new Cas(t) of characters enters the stage. Trends Cell Biol 2000;10:111-119 (Pubitemid 30110694)
29. Defilippi P, Di Stefano P, Cabodi S. p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol 2006;16:257-263 (Pubitemid 43728873)
30. Yan C, Boyd DD. Regulation of matrix metalloproteinase gene expression. J Cell Physiol 2007;211:19-26. (Pubitemid 46363892)
31. Csermely P, Schnaider T, Soti C, Prohaszka Z, Nardai G. The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review. Pharmacol Ther 1998;79:129-168
32. Boehm AK, Seth M, Mayr KG, Fortier LA. Hsp90 mediates insulin-like growth factor 1 and interleukin-1beta signaling in an age-dependent manner in equine articular chondrocytes. Arthritis Rheum 2007;56:2335-2343
33. Elo MA, Sironen RK, Karjalainen HM, Kaarniranta K, Helminen HJ, Lammi MJ. Specific induction of heat shock protein 90beta by high hydrostatic pressure. Biorheology 2003;40:141-146
34. Eustace BK, Jay DG. Extracellular roles for the molecular chaperone, hsp90. Cell Cycle 2004;3:1098-1100 (Pubitemid 40268620)
35. Chen B, Piel WH, Gui L, Bruford E, Monteiro A. The HSP90 family of genes in the human genome: insights into their divergence and evolution. Genomics 2005;86:627-633 (Pubitemid 41752943)