Mapping amorphous material on a partially crystalline surface: Nanothermal analysis for simultaneous characterisation and imaging of lactose compacts

Journal of Pharmaceutical Sciences

Volumn 98, Issue 4, 2009, Pages 1499-1510

  Dai, Xuan ^a   Reading, Mike ^a   Craig, Duncan Q M ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Amorphous; Atomic force microscopy; Glass transition; Lactose; Nanothermal analysis

Indexed keywords

LACTOSE;

ADHESION; ARTICLE; ATOMIC FORCE MICROSCOPY; CRYSTAL STRUCTURE; DRUG STRUCTURE; IMAGING SYSTEM; NANOANALYSIS; SURFACE PROPERTY; TEMPERATURE MEASUREMENT; THERMAL ANALYSIS; TOPOGRAPHY;

EID: 67449116269     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21538     Document Type: Article

References (28)

1. Buckton G, Darey P. 1999. Assessment of disorder in crystalline powders-A review of analytical techniques and their applications. Int J Pharm 179:141- 158.
2. Ahlneck EC, Aoderborn G, Nystrom C. 1994. Increased metastable solubility of milled griseoful- vin, depending on the formation of a disordered surface structure. Int J Pharm 111:159-170.
3. Morris KR, Griesser UJ, Eckhardt CJ, Stowell JG. 2001. Theoretical approaches to physical transformations of active pharmaceutical ingredients during manufacturing processes. Adv Drug Deliv Rev 48:91-114.
4. Young PM, Price R. 2004. The influence of humidity on the aerosolisation of micronised and SEDS produced salbutamol sulphate. Eur J Pharm Sci 22: 235-240.
5. Ahlneck C, Zografi G. 1990. The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state. Int J Pharm 62:87- 95.
6. Buckton G, Darcy P. 1995. The use of gravimetric studies to assess the degree of crystallinity of predominantly crystalline powders. Int J Pharm 123: 265-271.
7. Chen X, Bates S, Morris KR. 2001. Quantifying amorphous content of lactose using parallel beam X-ray powder diffraction and whole pattern fitting. J Pharm Biomed 26:63-72.
8. Dilworth S, Buckton G, Gaisford S, Ramos R. 2004. Approaches to determine the enthalpy of crystallisation, and amorphous content, of lactose from isothermal calorimetric data. Int J Pharm 284: 83-94.
9. Niemela P, Paalysaho M, Harjunen P, Koivisto M, Lehto VP, Suhonen J, Jarvinen K. 2005. Quantitative analysis of amorphous content of lactose using CCD-Raman spectrometry. J Pharm Biomed Anal 37:907-911.
10. Gombas A, Antal I, Szabo-Revesz P, Marton S, Eros I. 2003. Quantitative determination of crystallinity of alpha-laetose monohydrate by near infrared spectroscopy (NIRS). Int Pharm 256:25-32.
11. Lefort R, Gusseme AD, Willart JF, Danede F, Descamps M. 2004. Solid state NMR and DSC methods for quantifying the amorphous content in solid dosage forms: An application to ball-milling of trehalose. Int J Pharm 280:209-219.
12. Saleki-Gerhardt A, Ahlneck C, Zografi G. 1994. Assessment of disorder in crystalline solids. Int J Pharm 101:237-247.
13. Craig DQM, Barsnes M, Royall P, Kett V. 2000. An evaluation of the use of modulated temperature DSC as a means of assessing the relaxation behaviour of amorphous lactose. Pharm Res 17:696-700.
14. Saunders M, Podluii K, Shergill S, Buckton G, Royall P. 2004. The potential of high speed DSC (hyper-DSC) for the detection and quantification of small amounts of amorphous content in predominantly crystalline samples. Int J Pharm 274:35-40.
15. Katainen K, Niemela P, Harjunen P, Suhonen J, Jarvinen K. 2005. Evaluation of the amorphous content of lactose by solution calorimetry and Raman spectrometry. Talanta 68:1-5.
16. Begat P, Young PM, Edge S, Kaerger JS, Price R. 2003. The effect of mechanical processing on surface stability of pharmaceutical powders: Visualisation by atomic force microscopy. J Pharm Sci 92:611- 620.
17. Hammiche A, Reading M, Pollock HM, Song M, Hourston DJ. 1996. Localized thermal analysis using a miniaturized resistive probe. Rev Sci Instrum 67:4268-4274.
18. Hammiche A, Pollock HM, Reading M, Claybourn M, Turner PH, Jewkes K. 1999. Photothermal FT- IR spectroscopy: A step towards FT-IR microscopy at a resolution better than the diffraction limit. Appl Spectrosc 53:810-815.
19. Harding L, King WP, Dai X, Craig DQM, Reading M. 2007. Nanoscale characterisation and imaging of partially amorphous materials using local thermo-mechanical analysis and heated tip APM. Pharm Res 24:2048-2054.
20. King WP, Saxena S, Nelson BA, Weeks BL, Pitehimani R. 2006. Nanoscale thermal analysis of an energetic material. Nano Lett 6:2145-2149.
21. Harding L, Reading M, Craig DQM. 2007. The development of heated tip force-distance measurements as a novel approach to site-specific characterisation of pharmaceutical materials. J Pharm Sci 97:2768-2779.
22. Young PM, Price R, Tobyn MJ, Buttrum M, Dey F. 2004. The influence of relative humidity on the cohesion properties of micronized drugs used in inhalation therapy. J Pharm Sci 93:753-761.
23. Chaiyuta N, Amornsakchaia T, Thanawanb S. 2007. Force volume imaging of defects in highly drawn high-density polyethylene. Polyme Test 26: 396-401.
24. Gabroiaud F, Parcha BS, Gee ML, Holden JA, Strugnell RA. 2008. Spatially resolved force spectroscopy of bacterial surfaces using force-volume imaging. Colloid Surface B 62:206-213.
25. Mahlin D, Berggren J, Alderborn G, Engstrom S. 2004. Moistrue-induced surface crystallization of spray-dried amorphous lactose particles studied by atomic force microscopy. J Pharm Sci 93:29-37.
26. Briggner LE, Buckton G, Bystrom K, Darcy P. 1994. The use of isothermal microcalorimetry in the study of changes in crystallinity induced during the processing of powders. Int J Pharm 105:125-135.
27. Hill VL, Craig DQM, Feely LC. 1998. Characterisation of spray-dried lactose using modulated differential scanning calorimetry. Int J Pharm 161:95-107.
28. Grandy DB, Hourston DJ, Price DM, Reading M, Silva GG, Song M, Sykes P. 2000. Microthermal characterization of segmented polyurethane elastomers and a polystyrene-poly(methyl methacry- late) polyer blend using variable-temperature pulsed force mode atomic force microscopy. Macro-molecules 33:9348-9359.