Relationship of optic nerve and brain conventional and non-conventional MRI measures and retinal nerve fiber layer thickness, as assessed by OCT and GDx: A pilot study

Journal of the Neurological Sciences

Volumn 282, Issue 1-2, 2009, Pages 96-105

  Frohman, Elliot M ^a   Dwyer, Michael G ^b   Frohman, Teresa ^a   Cox, Jennifer L ^b   Salter, Amber ^a   Greenberg, Benjamin M ^a   Hussein, Sara ^b   Conger, Amy ^a   Calabresi, Peter ^c   Balcer, Laura J ^d   Zivadinov, Robert ^b,e  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e JACOBS NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Brain atrophy; Diffusion tensor imaging; GDx; Lesion volume; Low letter contrast acuity; Magnetization transfer imaging; MRI; Multiple sclerosis; OCT; Optic neuritis

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FEMALE; GRAY MATTER; HUMAN; MALE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE; OPTIC NERVE ATROPHY; OPTIC NEURITIS; OPTICAL COHERENCE TOMOGRAPHY; POLARIMETRY; PRIORITY JOURNAL; RETINA NERVE CELL; SCANNING LASER POLARIMETRY WITH VARIABLE CORNEAL COMPENSATION; THICKNESS; VISION TEST; VISUAL ACUITY;

ADULT; ANALYSIS OF VARIANCE; ATROPHY; BRAIN; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; OPTIC NERVE; OPTIC NEURITIS; ORGAN SIZE; PILOT PROJECTS; REGRESSION ANALYSIS; RETINA; TOMOGRAPHY, OPTICAL COHERENCE; VISION TESTS;

EID: 67349265946     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.04.010     Document Type: Article

References (34)

1. Frohman E.M., Racke M.K., and Raine C.S. Multiple sclerosis - the plaque and its pathogenesis. N Engl J Med 354 9 (2006) 942-955
2. Zivadinov R. Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis?. Neurology 68 3 (2007) S72-S82
3. Frohman E.M., Costello F., Zivadinov R., Stuve O., Conger A., Winslow H., et al. Optical coherence tomography in multiple sclerosis. Lancet Neurol 5 10 (2006) 853-863
4. Frohman E.M., Costello F., Stuve O., Calabresi P., Miller D.H., Hickman S.J., et al. Modeling axonal degeneration within the anterior visual system: implications for demonstrating neuroprotection in MS. Arch Neurol 65 1 (2008) 26-35
5. Trip S.A., Schlottmann P.G., Jones S.J., Altmann D.R., Garway-Heath D.F., Thompson A.J., et al. Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis. Ann Neurol 58 3 (2005) 383-391
6. Trip S.A., Schlottmann P.G., Jones S.J., Li W.Y., Garway-Heath D.F., Thompson A.J., et al. Optic nerve atrophy and retinal nerve fibre layer thinning following optic neuritis: evidence that axonal loss is a substrate of MRI-detected atrophy. Neuroimage 31 1 (2006) 286-293
7. Hickman S.J., Toosy A.T., Jones S.J., Altmann D.R., Miszkiel K.A., MacManus D.G., et al. A serial MRI study following optic nerve mean area in acute optic neuritis. Brain 127 Pt 11 (2004) 2498-2505
8. Hickman S.J., Toosy A.T., Jones S.J., Altmann D.R., Miszkiel K.A., MacManus D.G., et al. Serial magnetization transfer imaging in acute optic neuritis. Brain 127 Pt 3 (2004) 692-700
9. Hickman S.J., Wheeler-Kingshott C.A., Jones S.J., Miszkiel K.A., Barker G.J., Plant G.T., et al. Optic nerve diffusion measurement from diffusion-weighted imaging in optic neuritis. AJNR Am J Neuroradiol 26 4 (2005) 951-956
10. Trip S.A., Wheeler-Kingshott C., Jones S.J., Li W.Y., Barker G.J., Thompson A.J., et al. Optic nerve diffusion tensor imaging in optic neuritis. Neuroimage 30 2 (2006) 498-505
11. Naismith R.T., Xu J., Tutlam N.T., Snyder A., Benzinger T., Shimony J., et al. Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities. Neurology 72 7 (2009) 589-594
12. Gordon-Lipkin E., Chodkowski B., Reich D.S., Smith S.A., Pulicken M., Balcer L.J., et al. Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosis. Neurology 69 16 (2007) 1603-1609
13. Grazioli E., Zivadinov R., Weinstock-Guttman B., Lincoff N., Baier M., Wong J.R., et al. Retinal nerve fiber layer thickness is associated with brain MRI outcomes in multiple sclerosis. J Neurol Sci 268 1-2 (2008) 12-17
14. Siger M., Dziegielewski K., Jasek L., Bieniek M., Nicpan A., Nawrocki J., et al. Optical coherence tomography in multiple sclerosis: thickness of the retinal nerve fiber layer as a potential measure of axonal loss and brain atrophy. J Neurol 255 10 (2008) 1555-1560
15. Sepulcre J., Murie-Fernandez M., Salinas-Alaman A., Garcia-Layana A., Bejarano B., and Villoslada P. Diagnostic accuracy of retinal abnormalities in predicting disease activity in MS. Neurology 68 18 (2007) 1488-1494
16. Hickman S.J., Brierley C.M., Brex P.A., MacManus D.G., Scolding N.J., Compston D.A., et al. Continuing optic nerve atrophy following optic neuritis: a serial MRI study. Mult Scler 8 4 (2002) 339-342
17. Baker G., and Barnes N. Model-image registration of parametric shape models: fitting a shell to the cochlea. Insight J (2005) IJ-2005(MICCAI)
18. Ibanez L., Schroeder W., Ng L., and Cates J. The ITK software guide. 2 ed. (2005), Insight Software Consortium, Clifton Park, NY
19. Yoo T.S. Insight into images (2004), A K Peters, Ltd., Wellesey, MA
20. Woods R., Grafton S., Watson J., Sicotte N., and Mazziotta J. Automated image registration: II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr 22 1 (1998) 153-165 Comput Assist Tomogr 1998;22:153-65
21. Dwyer M.G., Fritz D., Cox J.L., Ambwani S., Saluste E., Matyas R., et al. One third of the anterior portion of the optic nerve is susceptible to motion of different eye direction. Proc Soc Magn Reson Med P2063 (2007) 407
22. Jiang H., van Zijl P.C., Kim J., Pearlson G.D., and Mori S. DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed 81 2 (2006) 106-116
23. Zivadinov R., Rudick R.A., De Masi R., Nasuelli D., Ukmar M., Pozzi-Mucelli R.S., et al. Effects of IV methylprednisolone on brain atrophy in relapsing-remitting MS. Neurology 57 7 (2001) 1239-1247
24. Smith S.M., Zhang Y., Jenkinson M., Chen J., Matthews P.M., Federico A., et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 17 1 (2002) 479-489
25. Zivadinov R., Weinstock-Guttman B., Benedict R., Tamano-Blanco M., Hussein S., Abdelrahman N., et al. Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain derived neurotrophic factor (BDNF). Hum Mol Genet 16 22 (2007) 2659-2668
26. Weinstock-Guttman B., Zivadinov R., Tamano-Blanco M., Abdelrahman N., Badgett D., Durfee J., et al. Immune cell BDNF secretion is associated with white matter volume in multiple sclerosis. J Neuroimmunol 188 1-2 (2007) 167-174
27. Benedict R.H.B., Bruce J., Dwyer M.G., Weinstock-Guttman B., Tjoa C., Tavazzi E., et al. Diffusion-weighted imaging predicts cognitive impairment in multiple sclerosis. Mult Scler 13 6 (2007) 722-730
28. Tavazzi E., Dwyer M.G., Weinstock-Guttman B., Lema J., Bastianello S., Bergamaschi R., et al. Quantitative diffusion weighted imaging measures in patients with multiple sclerosis. Neuroimage 36 3 (2007) 746-754
29. Fisher J.B., Jacobs D.A., Markowitz C.E., Galetta S.L., Volpe N.J., Nano-Schiavi M.L., et al. Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis. Ophthalmology 113 2 (2006) 324-332
30. Balcer L.J., Galetta S.L., Calabresi P.A., Confavreux C., Giovannoni G., Havrdova E., et al. Natalizumab reduces visual loss in patients with relapsing multiple sclerosis. Neurology 68 16 (2007) 1299-1304
31. Hickman S.J. Optic nerve imaging in multiple sclerosis. J Neuroimaging 17 Suppl 1 (2007) 42S-45S
32. Wu G.F., Schwartz E.D., Lei T., Souza A., Mishra S., Jacobs D.A., et al. Relation of vision to global and regional brain MRI in multiple sclerosis. Neurology 69 23 (2007) 2128-2135
33. Cettomai D., Pulicken M., Gordon-Lipkin E., Salter A., Frohman T.C., Conger A., et al. Reproducibility of optical coherence tomography in multiple sclerosis. Arch Neurol 65 9 (2008) 1218-1222
34. Zaveri M.S., Conger A., Salter A., Frohman T.C., Galetta S.L., Markowitz C.E., et al. Retinal imaging by laser polarimetry and optical coherence tomography evidence of axonal degeneration in multiple sclerosis. Arch Neurol 65 7 (2008) 924-928