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Volumn 614, Issue 1-3, 2009, Pages 70-76

Preventive effects of raloxifene, a selective estrogen receptor modulator, on monocrotaline-induced pulmonary hypertension in intact and ovariectomized female rats

Author keywords

Endothelin 1; Female rat; Monocrotaline; Ovariectomy; Pulmonary hypertension; Raloxifene

Indexed keywords

ENDOTHELIN 1; MONOCROTALINE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SODIUM CHLORIDE;

EID: 67349250518     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.04.016     Document Type: Article
Times cited : (10)

References (50)
  • 1
    • 0346964663 scopus 로고    scopus 로고
    • Estrogen and enalapril attenuate the development of right ventricular hypertrophy induced by monocrotaline in ovariectomized rats
    • Ahn B.H., Park H.K., Cho H.G., Lee H.A., Lee Y.M., Yang E.K., and Lee W.J. Estrogen and enalapril attenuate the development of right ventricular hypertrophy induced by monocrotaline in ovariectomized rats. J. Korean Med. Sci. 18 (2003) 641-648
    • (2003) J. Korean Med. Sci. , vol.18 , pp. 641-648
    • Ahn, B.H.1    Park, H.K.2    Cho, H.G.3    Lee, H.A.4    Lee, Y.M.5    Yang, E.K.6    Lee, W.J.7
  • 2
    • 41449090802 scopus 로고    scopus 로고
    • Genetic and pharmacological strategies to determine the function of estrogen receptor α and estrogen receptor β in the cardiovascular system
    • Arias-Loza P.A., Jazbutyte V., and Pelzer T. Genetic and pharmacological strategies to determine the function of estrogen receptor α and estrogen receptor β in the cardiovascular system. Gen. Med. 5 (2008) S34-S45
    • (2008) Gen. Med. , vol.5
    • Arias-Loza, P.A.1    Jazbutyte, V.2    Pelzer, T.3
  • 4
    • 33947605035 scopus 로고    scopus 로고
    • Hormone replacement therapy may prevent the development of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement
    • Beretta L., Caronni M., Origgi L., Ponti A., Santaniello A., and Scorza R. Hormone replacement therapy may prevent the development of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Scand. J. Rheumatol. 35 (2006) 468-471
    • (2006) Scand. J. Rheumatol. , vol.35 , pp. 468-471
    • Beretta, L.1    Caronni, M.2    Origgi, L.3    Ponti, A.4    Santaniello, A.5    Scorza, R.6
  • 6
    • 0036240126 scopus 로고    scopus 로고
    • Mechanism of raloxifene-induced relaxation in femoral veins depends on ovarian hormonal status
    • Bracamonte M.P., Rud K.S., and Miller V.M. Mechanism of raloxifene-induced relaxation in femoral veins depends on ovarian hormonal status. J. Cardiovasc. Pharmacol. 39 (2002) 704-713
    • (2002) J. Cardiovasc. Pharmacol. , vol.39 , pp. 704-713
    • Bracamonte, M.P.1    Rud, K.S.2    Miller, V.M.3
  • 9
    • 0032851148 scopus 로고    scopus 로고
    • 2+ entry mechanisms of arterial vasoconstriction by sex hormones
    • 2+ entry mechanisms of arterial vasoconstriction by sex hormones. Clin. Exp. Pharmacol. Physiol. 26 (1999) 707-715
    • (1999) Clin. Exp. Pharmacol. Physiol. , vol.26 , pp. 707-715
    • Crews, J.K.1    Khalil, R.A.2
  • 10
    • 33750292973 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension and women
    • De, and Marco T. Pulmonary arterial hypertension and women. Cardiol. Rev. 14 (2006) 312-318
    • (2006) Cardiol. Rev. , vol.14 , pp. 312-318
    • De1    Marco, T.2
  • 11
    • 34548857909 scopus 로고    scopus 로고
    • Effect of ovariectomy on renal estrogen receptor-α and estrogen receptor-β in young salt-sensitive and -resistant rats
    • Esqueda M.E., Craig T., and Hinojosa-Laborde C. Effect of ovariectomy on renal estrogen receptor-α and estrogen receptor-β in young salt-sensitive and -resistant rats. Hypertension 50 (2007) 768-772
    • (2007) Hypertension , vol.50 , pp. 768-772
    • Esqueda, M.E.1    Craig, T.2    Hinojosa-Laborde, C.3
  • 12
    • 0027165908 scopus 로고
    • Protection by oestradiol against the development of cardiovascular changes associated with monocrotaline pulmonary hypertension in rats
    • Farhat M.Y., Chen M.F., Bhatti T., Iqbal A., Cathapermal S., and Ramwell P.W. Protection by oestradiol against the development of cardiovascular changes associated with monocrotaline pulmonary hypertension in rats. Br. J. Pharmacol. 110 (1993) 719-723
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 719-723
    • Farhat, M.Y.1    Chen, M.F.2    Bhatti, T.3    Iqbal, A.4    Cathapermal, S.5    Ramwell, P.W.6
  • 14
    • 33645877184 scopus 로고
    • Hormonal modification of the sex differences following monocrotaline administration
    • Goldenthal E.I., D'Aguanno W., and Lynch J.F. Hormonal modification of the sex differences following monocrotaline administration. Toxicol. Appl. Pharmacol. 6 (1964) 434-441
    • (1964) Toxicol. Appl. Pharmacol. , vol.6 , pp. 434-441
    • Goldenthal, E.I.1    D'Aguanno, W.2    Lynch, J.F.3
  • 15
    • 0030862759 scopus 로고    scopus 로고
    • Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats
    • Hill N.S., Warburton R.R., Pietras L., and Klinger J.R. Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats. J. Appl. Physiol. 83 (1997) 1209-1215
    • (1997) J. Appl. Physiol. , vol.83 , pp. 1209-1215
    • Hill, N.S.1    Warburton, R.R.2    Pietras, L.3    Klinger, J.R.4
  • 16
    • 0029871898 scopus 로고    scopus 로고
    • Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium
    • Ichikawa K.I., Hidai C., Okuda C., Kimata S.I., Matsuoka R., Hosoda S., Quertermous T., and Kawana M. Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium. J. Am. Coll. Cardiol. 27 (1996) 1286-1291
    • (1996) J. Am. Coll. Cardiol. , vol.27 , pp. 1286-1291
    • Ichikawa, K.I.1    Hidai, C.2    Okuda, C.3    Kimata, S.I.4    Matsuoka, R.5    Hosoda, S.6    Quertermous, T.7    Kawana, M.8
  • 21
    • 34548437943 scopus 로고    scopus 로고
    • Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle
    • Lahm T., Patel K.M., Crisostomo P.R., Markel T.A., Wang M., Herring C., and Meldrum D.R. Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle. Am. J. Physiol. 293 (2007) E865-E871
    • (2007) Am. J. Physiol. , vol.293
    • Lahm, T.1    Patel, K.M.2    Crisostomo, P.R.3    Markel, T.A.4    Wang, M.5    Herring, C.6    Meldrum, D.R.7
  • 22
    • 47249115325 scopus 로고    scopus 로고
    • The effects of estrogen on pulmonary artery vasoreactivity and hypoxic pulmonary vasoconstriction: potential new clinical implications for an old hormone
    • Lahm T., Crisostomo P.R., Markel T.A., Wang M., Weil B.R., Novotny N.M., and Meldrum D.R. The effects of estrogen on pulmonary artery vasoreactivity and hypoxic pulmonary vasoconstriction: potential new clinical implications for an old hormone. Crit. Care Med. 36 (2008) 2174-2183
    • (2008) Crit. Care Med. , vol.36 , pp. 2174-2183
    • Lahm, T.1    Crisostomo, P.R.2    Markel, T.A.3    Wang, M.4    Weil, B.R.5    Novotny, N.M.6    Meldrum, D.R.7
  • 24
    • 0025218531 scopus 로고
    • Conversion of porcine big endothelin by an extract from the porcine aortic endothelial cells
    • Matsumura Y., Ikegawa R., Takaoka M., and Morimoto S. Conversion of porcine big endothelin by an extract from the porcine aortic endothelial cells. Biochem. Biophys. Res. Commun. 167 (1990) 203-210
    • (1990) Biochem. Biophys. Res. Commun. , vol.167 , pp. 203-210
    • Matsumura, Y.1    Ikegawa, R.2    Takaoka, M.3    Morimoto, S.4
  • 25
    • 46949109892 scopus 로고    scopus 로고
    • Vascular actions of estrogens: functional implications
    • Miller V.M., and Duckles S.P. Vascular actions of estrogens: functional implications. Pharmacol. Rev. 60 (2008) 210-241
    • (2008) Pharmacol. Rev. , vol.60 , pp. 210-241
    • Miller, V.M.1    Duckles, S.P.2
  • 26
    • 0027449163 scopus 로고
    • Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension
    • Miyauchi T., Yorikane R., Sakai S., Sakurai T., Okada M., Nishikibe M., Yano M., Yamaguchi I., Sugishita Y., and Goto K. Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension. Circ. Res. 73 (1993) 887-897
    • (1993) Circ. Res. , vol.73 , pp. 887-897
    • Miyauchi, T.1    Yorikane, R.2    Sakai, S.3    Sakurai, T.4    Okada, M.5    Nishikibe, M.6    Yano, M.7    Yamaguchi, I.8    Sugishita, Y.9    Goto, K.10
  • 29
    • 67349194394 scopus 로고    scopus 로고
    • Raloxifene regulates endothelin-1 gene expression through the AMPK-induced NO production in cultured pulmonary artery endothelial cells
    • Ohkuma S., Ohkita M., Kawabata E., Hiramatsu A., Nishida M., and Matsumura Y. Raloxifene regulates endothelin-1 gene expression through the AMPK-induced NO production in cultured pulmonary artery endothelial cells. J. Pharmacol. Sci. 106 Suppl.I (2008) 214pp.
    • (2008) J. Pharmacol. Sci. , vol.106 , Issue.SUPPL.I
    • Ohkuma, S.1    Ohkita, M.2    Kawabata, E.3    Hiramatsu, A.4    Nishida, M.5    Matsumura, Y.6
  • 31
    • 4644342416 scopus 로고    scopus 로고
    • Raloxifene increases the capacity of serum to promote prostacyclin release human endothelial cells: implication of COX-1 and COX-2
    • Oviedo P.J., Hermenegildo C., and Cano A. Raloxifene increases the capacity of serum to promote prostacyclin release human endothelial cells: implication of COX-1 and COX-2. Menopause 11 (2004) 430-437
    • (2004) Menopause , vol.11 , pp. 430-437
    • Oviedo, P.J.1    Hermenegildo, C.2    Cano, A.3
  • 33
  • 34
    • 0019482038 scopus 로고
    • Age and sex influence on pulmonary hypertension of chronic hypoxia and on recovery
    • Rabinovitch M., Gamble W.J., Miettinen O.S., and Reid L. Age and sex influence on pulmonary hypertension of chronic hypoxia and on recovery. Am. J. Physiol. 240 (1981) H62-H72
    • (1981) Am. J. Physiol. , vol.240
    • Rabinovitch, M.1    Gamble, W.J.2    Miettinen, O.S.3    Reid, L.4
  • 35
    • 0035015033 scopus 로고    scopus 로고
    • Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression
    • Resta T.C., Kanagy N.L., and Walker B.R. Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression. Am. J. Physiol. 280 (2001) L88-L97
    • (2001) Am. J. Physiol. , vol.280
    • Resta, T.C.1    Kanagy, N.L.2    Walker, B.R.3
  • 38
    • 0035081412 scopus 로고    scopus 로고
    • Effects of the oestrous cycle and gender on acute vasodilatory responses of isolated pressurized rat mesenteric arteries to 17β-oestradiol
    • Shaw L., Taggart M., and Austin C. Effects of the oestrous cycle and gender on acute vasodilatory responses of isolated pressurized rat mesenteric arteries to 17β-oestradiol. Br. J. Pharmacol. 132 (2001) 1055-1062
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 1055-1062
    • Shaw, L.1    Taggart, M.2    Austin, C.3
  • 39
    • 85042587042 scopus 로고    scopus 로고
    • Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause
    • Serock M.R., Wells A.K., and Khalil R.A. Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause. Recent. Pat. Cardiovasc. Drug. Discov. 3 (2008) 165-186
    • (2008) Recent. Pat. Cardiovasc. Drug. Discov. , vol.3 , pp. 165-186
    • Serock, M.R.1    Wells, A.K.2    Khalil, R.A.3
  • 40
    • 1242341961 scopus 로고    scopus 로고
    • Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy
    • Shohet R.V., Kisanuki Y.Y., Zhao X.S., Siddiquee Z., Franco F., and Yanagisawa M. Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 2088-2093
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 2088-2093
    • Shohet, R.V.1    Kisanuki, Y.Y.2    Zhao, X.S.3    Siddiquee, Z.4    Franco, F.5    Yanagisawa, M.6
  • 41
    • 0025221348 scopus 로고
    • Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes
    • Shubeita H.E., McDonough P.M., Harris A.N., Knowlton K.U., Glembotski C.C., Brown J.H., and Chien K.R. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. J. Biol. Chem. 265 (1990) 20555-20562
    • (1990) J. Biol. Chem. , vol.265 , pp. 20555-20562
    • Shubeita, H.E.1    McDonough, P.M.2    Harris, A.N.3    Knowlton, K.U.4    Glembotski, C.C.5    Brown, J.H.6    Chien, K.R.7
  • 43
    • 33644859606 scopus 로고    scopus 로고
    • The influence of sex hormones on pulmonary vascular reactivity: possible vasodilator therapies for the treatment of pulmonary hypertension
    • Smith A.M., Jones1 R.D., and Channer K.S. The influence of sex hormones on pulmonary vascular reactivity: possible vasodilator therapies for the treatment of pulmonary hypertension. Curr. Vasc. Pharmacol. 4 (2006) 9-15
    • (2006) Curr. Vasc. Pharmacol. , vol.4 , pp. 9-15
    • Smith, A.M.1    Jones1, R.D.2    Channer, K.S.3
  • 45
    • 33751080146 scopus 로고    scopus 로고
    • 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension
    • Tofovic S.P., Zhang X., Jackson E.K., Dacic S., and Petrusevska G. 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension. Vasc. Pharmacol. 45 (2006) 358-367
    • (2006) Vasc. Pharmacol. , vol.45 , pp. 358-367
    • Tofovic, S.P.1    Zhang, X.2    Jackson, E.K.3    Dacic, S.4    Petrusevska, G.5
  • 47
    • 0037197781 scopus 로고    scopus 로고
    • Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production
    • Wassmann S., Laufs U., Stamenkovic D., Linz W., Stasch J.P., Ahlbory K., Rösen R., Böhm M., and Nickenig G. Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production. Circulation 105 (2002) 2083-2091
    • (2002) Circulation , vol.105 , pp. 2083-2091
    • Wassmann, S.1    Laufs, U.2    Stamenkovic, D.3    Linz, W.4    Stasch, J.P.5    Ahlbory, K.6    Rösen, R.7    Böhm, M.8    Nickenig, G.9
  • 49
    • 1642453774 scopus 로고    scopus 로고
    • Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice
    • Yang L.L., Gros R., Kabir M.G., Sadi A., Gotlieb A.I., Husain M., and Stewart D.J. Conditional cardiac overexpression of endothelin-1 induces inflammation and dilated cardiomyopathy in mice. Circulation 109 (2004) 255-261
    • (2004) Circulation , vol.109 , pp. 255-261
    • Yang, L.L.1    Gros, R.2    Kabir, M.G.3    Sadi, A.4    Gotlieb, A.I.5    Husain, M.6    Stewart, D.J.7
  • 50
    • 33748419940 scopus 로고    scopus 로고
    • Hemodynamic effects of acute and repeated exposure to raloxifene in ovariectomized sheep
    • Zoma W.D., Baker R.S., Mershon J.L., and Clark K.E. Hemodynamic effects of acute and repeated exposure to raloxifene in ovariectomized sheep. Am. J. Physiol. 291 (2006) H1216-H1225
    • (2006) Am. J. Physiol. , vol.291
    • Zoma, W.D.1    Baker, R.S.2    Mershon, J.L.3    Clark, K.E.4


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