Rapid and quantitative detection of CpG-methylation status using TaqMan PCR combined with methyl-binding-domain polypeptide

Clinical Biochemistry

Volumn 42, Issue 10-11, 2009, Pages 1113-1122

  Kimura, Naoki ^a   Moribe, Toyoki ^a   Iizuka, Norio ^b   Miura, Toshiaki ^a   Tamatsukuri, Shigeru ^a   Ishitsuka, Hideo ^a   Hamamoto, Yoshihiko ^c   Oka, Masaaki ^b  

^a Research Group   (Japan)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Methyl binding domain polypeptide; Methylation; TaqMan PCR

Indexed keywords

APC PROTEIN; METHYL BINDING DOMAIN POLYPEPTIDE; POLYPEPTIDE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TUMOR MARKER; UNCLASSIFIED DRUG;

ANALYTICAL EQUIPMENT; ARTICLE; CANCER DIAGNOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIAGNOSTIC VALUE; DNA DETERMINATION; DNA METHYLATION; DNA SEQUENCE; FEMALE; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; METAL BINDING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RELIABILITY;

ADENOMATOUS POLYPOSIS COLI; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASMS; PEPTIDES; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; SENSITIVITY AND SPECIFICITY; TUMOR SUPPRESSOR PROTEINS;

EID: 67349243496     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2009.03.017     Document Type: Article

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