Hexane fraction of Zingiberis Rhizoma Crudus extract inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated BV2 microglial cells via the NF-kappaB pathway

Food and Chemical Toxicology

Volumn 47, Issue 6, 2009, Pages 1190-1197

  Jung, Hyo Won ^a   Yoon, Cheol Ho ^a   Park, Kwon Moo ^b   Han, Hyung Soo ^c   Park, Yong Ki ^a  

^a Dongguk University   (South Korea)

^b School of Medicine   (South Korea)

^c Kyungpook National University Hospital   (South Korea)

Author keywords

Anti inflammation; Cytokine; Microglia; Nitric oxide; Nuclear factor kappaB; Zingiber officinale

Indexed keywords

CYCLOOXYGENASE 2; GINGER EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; CELL ACTIVATION; CELL LINE; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; GENE; MICROGLIA; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CYTOKINES; DINOPROSTONE; GINGER; HEXANES; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOLVENTS;

ZINGIBER OFFICINALE; ZINGIBERIS;

EID: 67349236219     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.02.012     Document Type: Article

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