Disruption of estrogen receptor α-p53 interaction in breast tumors: A novel mechanism underlying the anti-tumor effect of radiation therapy

Breast Cancer Research and Treatment

Volumn 115, Issue 1, 2009, Pages 43-50

  Liu, Wensheng ^a   Ip, Margot M ^a   Podgorsak, Matthew B ^a   Das, Gokul M ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Breast cancer; Chromatin immunoprecipitation; Estrogen receptor ; Ionizing radiation; P21; Radiation therapy; Real time PCR; Survivin; Tumor growth; Tumor suppressor p53; Xenograft mouse model

Indexed keywords

ESTROGEN RECEPTOR ALPHA; PROTEIN P53; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CANCER CELL; CANCER INHIBITION; CANCER RADIOTHERAPY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TUMOR XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NEOPLASM TRANSPLANTATION; PROMOTER REGIONS, GENETIC; RADIOTHERAPY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 67349233602     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0044-z     Document Type: Article

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