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Volumn 315, Issue 11, 2009, Pages 1860-1874

Generation and properties of a new human ventral mesencephalic neural stem cell line

Author keywords

Dopaminergic neurons; Human neural stem cells; Immortalization; Parkinson's disease; Ventral mesencephalon

Indexed keywords

DOPAMINE; NESTIN; NEUROGENIN 2; ONCOPROTEIN; TRANSCRIPTION FACTOR MASH1; VIMENTIN;

EID: 67349231164     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.03.011     Document Type: Article
Times cited : (44)

References (59)
  • 1
    • 0036909332 scopus 로고    scopus 로고
    • Stem cells for neurodegenerative disorders: where can we go from here?
    • Le Belle J.E., and Svendsen C.N. Stem cells for neurodegenerative disorders: where can we go from here?. BioDrugs 16 (2002) 389-401
    • (2002) BioDrugs , vol.16 , pp. 389-401
    • Le Belle, J.E.1    Svendsen, C.N.2
  • 2
    • 3142521479 scopus 로고    scopus 로고
    • Stem cell therapy for human neurodegenerative disorders-how to make it work
    • (Suppl.)
    • Lindvall O., Kokaia Z., and Martinez-Serrano A. Stem cell therapy for human neurodegenerative disorders-how to make it work. Nat. Med. 10 (2004) S42-50 (Suppl.)
    • (2004) Nat. Med. , vol.10
    • Lindvall, O.1    Kokaia, Z.2    Martinez-Serrano, A.3
  • 3
    • 24944508086 scopus 로고    scopus 로고
    • Stem and progenitor cell-based therapy of the human central nervous system
    • Goldman S. Stem and progenitor cell-based therapy of the human central nervous system. Nat. Biotechnol. 23 (2005) 862-871
    • (2005) Nat. Biotechnol. , vol.23 , pp. 862-871
    • Goldman, S.1
  • 4
    • 33745601099 scopus 로고    scopus 로고
    • Stem cells for the treatment of neurological disorders
    • Lindvall O., and Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 441 (2006) 1094-1096
    • (2006) Nature , vol.441 , pp. 1094-1096
    • Lindvall, O.1    Kokaia, Z.2
  • 9
    • 13144259693 scopus 로고    scopus 로고
    • Cell transplantation in Parkinson's disease: how can we make it work?
    • Winkler C., Kirik D., and Bjorklund A. Cell transplantation in Parkinson's disease: how can we make it work?. Trends Neurosci. 28 (2005) 86-92
    • (2005) Trends Neurosci. , vol.28 , pp. 86-92
    • Winkler, C.1    Kirik, D.2    Bjorklund, A.3
  • 10
    • 0036096908 scopus 로고    scopus 로고
    • Stem cells in the treatment of Parkinson's disease
    • Arenas E. Stem cells in the treatment of Parkinson's disease. Brain Res. Bull. 57 (2002) 795-808
    • (2002) Brain Res. Bull. , vol.57 , pp. 795-808
    • Arenas, E.1
  • 11
    • 23344449323 scopus 로고    scopus 로고
    • Stem cell treatment for Parkinson's disease: an update for 2005
    • Snyder B.J., and Olanow C.W. Stem cell treatment for Parkinson's disease: an update for 2005. Curr. Opinion Neurobiol. 18 (2005) 376-385
    • (2005) Curr. Opinion Neurobiol. , vol.18 , pp. 376-385
    • Snyder, B.J.1    Olanow, C.W.2
  • 12
    • 34347397011 scopus 로고    scopus 로고
    • Stem-cell-based strategies for the treatment of Parkinson's disease
    • Parish C.L., and Arenas E. Stem-cell-based strategies for the treatment of Parkinson's disease. Neurobiol. Dis. 4 (2007) 339-347
    • (2007) Neurobiol. Dis. , vol.4 , pp. 339-347
    • Parish, C.L.1    Arenas, E.2
  • 16
    • 33750706917 scopus 로고    scopus 로고
    • Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
    • Roy N., Cleren C., Singh S.K., Yang L., Beal M.F., and Goldman S. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat. Med. 12 (2006) 1259-1268
    • (2006) Nat. Med. , vol.12 , pp. 1259-1268
    • Roy, N.1    Cleren, C.2    Singh, S.K.3    Yang, L.4    Beal, M.F.5    Goldman, S.6
  • 17
    • 33846904764 scopus 로고    scopus 로고
    • Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using bone morphogenic protein antagonist noggin
    • Sonntag K.C., Pruszak J., Yoshizaki T., van Arensbergen J., Sanchez-Pernaute R., and Isacson O. Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using bone morphogenic protein antagonist noggin. Stem Cells 25 (2007) 411-418
    • (2007) Stem Cells , vol.25 , pp. 411-418
    • Sonntag, K.C.1    Pruszak, J.2    Yoshizaki, T.3    van Arensbergen, J.4    Sanchez-Pernaute, R.5    Isacson, O.6
  • 18
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer L., Tabar V., and McKay R.D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat. Neurosci. 1 (1998) 290-295
    • (1998) Nat. Neurosci. , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.3
  • 19
    • 0032918328 scopus 로고    scopus 로고
    • Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons
    • Potter E.D., Ling Z.D., and Carvey P.M. Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons. Cell Tissue Res. 296 (1999) 235-246
    • (1999) Cell Tissue Res. , vol.296 , pp. 235-246
    • Potter, E.D.1    Ling, Z.D.2    Carvey, P.M.3
  • 20
    • 0034307725 scopus 로고    scopus 로고
    • Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
    • Studer L., Csete M., Lee S.H., Kabbani N., Walikonis J., Wold B., and McKay R. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J. Neurosci. 20 (2000) 7377-7383
    • (2000) J. Neurosci. , vol.20 , pp. 7377-7383
    • Studer, L.1    Csete, M.2    Lee, S.H.3    Kabbani, N.4    Walikonis, J.5    Wold, B.6    McKay, R.7
  • 21
    • 0034871846 scopus 로고    scopus 로고
    • Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells
    • Storch A., Paul G., Csete M., Boehm B.O., Carvey P.M., Kupsch A., and Schwarz J. Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells. Exp. Neurol. 170 (2001) 317-325
    • (2001) Exp. Neurol. , vol.170 , pp. 317-325
    • Storch, A.1    Paul, G.2    Csete, M.3    Boehm, B.O.4    Carvey, P.M.5    Kupsch, A.6    Schwarz, J.7
  • 22
    • 10044264235 scopus 로고    scopus 로고
    • The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo
    • Liste I., Garcia-Garcia E., and Martinez-Serrano A. The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo. J. Neurosci. 24 (2004) 10786-10795
    • (2004) J. Neurosci. , vol.24 , pp. 10786-10795
    • Liste, I.1    Garcia-Garcia, E.2    Martinez-Serrano, A.3
  • 23
    • 33751507706 scopus 로고    scopus 로고
    • Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells
    • Vergano-Vera E., Yusta-Boyo M.J., de Castro F., Bernard A., de Pablo F., and Vicario-Abejon C. Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells. Development 133 (2006) 4367-4379
    • (2006) Development , vol.133 , pp. 4367-4379
    • Vergano-Vera, E.1    Yusta-Boyo, M.J.2    de Castro, F.3    Bernard, A.4    de Pablo, F.5    Vicario-Abejon, C.6
  • 26
    • 0035453310 scopus 로고    scopus 로고
    • Human neural stem and progenitor cells: in vitro and in vivo properties, and potential for gene therapy and cell replacement in the CNS
    • Martinez-Serrano A., Rubio F.J., Navarro B., Bueno C., and Villa A. Human neural stem and progenitor cells: in vitro and in vivo properties, and potential for gene therapy and cell replacement in the CNS. Curr. Gene Ther. 1 (2001) 279-299
    • (2001) Curr. Gene Ther. , vol.1 , pp. 279-299
    • Martinez-Serrano, A.1    Rubio, F.J.2    Navarro, B.3    Bueno, C.4    Villa, A.5
  • 28
    • 0742305862 scopus 로고    scopus 로고
    • Using human neural stem cells to model neurological disease
    • Jakel R.J., Schneider B.L., and Svendsen C.N. Using human neural stem cells to model neurological disease. Nat. Rev. Genet. 5 (2004) 136-144
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 136-144
    • Jakel, R.J.1    Schneider, B.L.2    Svendsen, C.N.3
  • 29
    • 0031015438 scopus 로고    scopus 로고
    • Regulation of voltage- and ligand-gated currents in rat hippocampal progenitor cells in vitro
    • Sah D.W., Ray J., and Gage F.H. Regulation of voltage- and ligand-gated currents in rat hippocampal progenitor cells in vitro. J. Neurobiol. 32 (1997) 95-110
    • (1997) J. Neurobiol. , vol.32 , pp. 95-110
    • Sah, D.W.1    Ray, J.2    Gage, F.H.3
  • 30
    • 0031889823 scopus 로고    scopus 로고
    • A truncated SV40 large T antigen lacking the p53 binding domain overcomes p53-induced growth arrest and immortalizes primary mesencephalic cells
    • Truckenmiller M.E., Tornatore C., Wright R.D., Dillon-Carter O., Meiners S., Geller H.M., and Freed W.J. A truncated SV40 large T antigen lacking the p53 binding domain overcomes p53-induced growth arrest and immortalizes primary mesencephalic cells. Cell Tissue Res. 291 (1998) 175-189
    • (1998) Cell Tissue Res. , vol.291 , pp. 175-189
    • Truckenmiller, M.E.1    Tornatore, C.2    Wright, R.D.3    Dillon-Carter, O.4    Meiners, S.5    Geller, H.M.6    Freed, W.J.7
  • 31
    • 0037064078 scopus 로고    scopus 로고
    • Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line
    • Lotharius J., Barg S., Wiekop P., Lundberg C., Raymon H.K., and Brundin P. Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J. Biol. Chem. 277 (2002) 38884-38894
    • (2002) J. Biol. Chem. , vol.277 , pp. 38884-38894
    • Lotharius, J.1    Barg, S.2    Wiekop, P.3    Lundberg, C.4    Raymon, H.K.5    Brundin, P.6
  • 32
    • 33847314150 scopus 로고    scopus 로고
    • Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line-studies in vitro and after intracerebral grafting in vivo
    • Paul G., Christophersen N.S., Raymon H., Kiaer C., Smith R., and Brundin P. Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line-studies in vitro and after intracerebral grafting in vivo. Mol. Cell. Neurosci. 34 (2007) 390-399
    • (2007) Mol. Cell. Neurosci. , vol.34 , pp. 390-399
    • Paul, G.1    Christophersen, N.S.2    Raymon, H.3    Kiaer, C.4    Smith, R.5    Brundin, P.6
  • 33
    • 39149087389 scopus 로고    scopus 로고
    • Retrovirally mediated telomerase immortalization of neural progenitor cells
    • Roy N.S., Chandler-Militello D., Lu G., Wang S., and Goldman S.A. Retrovirally mediated telomerase immortalization of neural progenitor cells. Nat. Protoc. 2 (2007) 2815-2825
    • (2007) Nat. Protoc. , vol.2 , pp. 2815-2825
    • Roy, N.S.1    Chandler-Militello, D.2    Lu, G.3    Wang, S.4    Goldman, S.A.5
  • 35
    • 0034008662 scopus 로고    scopus 로고
    • Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS
    • Villa A., Snyder E.Y., Vescovi A., and Martinez-Serrano A. Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS. Exp. Neurol 161 (2000) 67-84
    • (2000) Exp. Neurol , vol.161 , pp. 67-84
    • Villa, A.1    Snyder, E.Y.2    Vescovi, A.3    Martinez-Serrano, A.4
  • 37
    • 34547154713 scopus 로고    scopus 로고
    • HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy
    • Khan Z., Akhtar M., Asklund T., Juliusson B., Almquist P.M., and Ekström T.J. HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy. Exp. Cell. Res. 313 (2007) 2958-2967
    • (2007) Exp. Cell. Res. , vol.313 , pp. 2958-2967
    • Khan, Z.1    Akhtar, M.2    Asklund, T.3    Juliusson, B.4    Almquist, P.M.5    Ekström, T.J.6
  • 39
    • 67349173289 scopus 로고    scopus 로고
    • Bcl-XL enhances the neurogenic capacity and dopamine neuron production by human ventral mesencephalic neural stem/precursor cells
    • No 825.10.
    • Liste I., Villa A., Bueno C., Juliusson B., Kusk P., Courtois E., and Martinez-Serrano A. Bcl-XL enhances the neurogenic capacity and dopamine neuron production by human ventral mesencephalic neural stem/precursor cells. Society Neurosci. Abstr. (2004) No 825.10.
    • (2004) Society Neurosci. Abstr.
    • Liste, I.1    Villa, A.2    Bueno, C.3    Juliusson, B.4    Kusk, P.5    Courtois, E.6    Martinez-Serrano, A.7
  • 41
    • 35548987545 scopus 로고    scopus 로고
    • Bcl-XL modulates the differentiation of immortalized human neural stem cells
    • Liste I., Garcia-Garcia E., Bueno C., and Martinez-Serrano A. Bcl-XL modulates the differentiation of immortalized human neural stem cells. Cell Death Diff. 14 (2007) 1880-1892
    • (2007) Cell Death Diff. , vol.14 , pp. 1880-1892
    • Liste, I.1    Garcia-Garcia, E.2    Bueno, C.3    Martinez-Serrano, A.4
  • 42
    • 0037198603 scopus 로고    scopus 로고
    • The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro
    • Riaz S.S., Jauniaux E., Stern G.M., and Bradford H.F. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain Res. 136 (2002) 27-34
    • (2002) Brain Res. , vol.136 , pp. 27-34
    • Riaz, S.S.1    Jauniaux, E.2    Stern, G.M.3    Bradford, H.F.4
  • 43
    • 34447334838 scopus 로고    scopus 로고
    • Expansion and characterization of ventral mesencephalic precursor cells: effect of mitogens and investigation of FA1 as a potential dopaminergic marker
    • Jensen P., Bauer M., Jensen C.H., Widmer H.R., Gramsbergen J.B., Blaabjerg M., Zimmer J., and Meyer M. Expansion and characterization of ventral mesencephalic precursor cells: effect of mitogens and investigation of FA1 as a potential dopaminergic marker. J. Neurosci. Res 85 (2007) 1884-1893
    • (2007) J. Neurosci. Res , vol.85 , pp. 1884-1893
    • Jensen, P.1    Bauer, M.2    Jensen, C.H.3    Widmer, H.R.4    Gramsbergen, J.B.5    Blaabjerg, M.6    Zimmer, J.7    Meyer, M.8
  • 44
    • 33847643776 scopus 로고    scopus 로고
    • Quantification of mRNA using real time RT-PCR
    • Nolan T., Hands R.E., and Bustin S.A. Quantification of mRNA using real time RT-PCR. Nat. Protocol. 3 (2006) 1561-1582
    • (2006) Nat. Protocol. , vol.3 , pp. 1561-1582
    • Nolan, T.1    Hands, R.E.2    Bustin, S.A.3
  • 45
    • 12744251664 scopus 로고    scopus 로고
    • Isolation, proliferation, survival and differentiation of human neural stem/precursor cells in vitro and in vivo. A focus on their potential clinical applications
    • Bottenstein J.E. (Ed), Kluwer Academic Publisher, Dordrecht
    • Navarro B., Villa A., Liste I., Bueno C., and Martinez-Serrano A. Isolation, proliferation, survival and differentiation of human neural stem/precursor cells in vitro and in vivo. A focus on their potential clinical applications. In: Bottenstein J.E. (Ed). Neural Stem Cells: Development and Transplantation (2003), Kluwer Academic Publisher, Dordrecht 271-298
    • (2003) Neural Stem Cells: Development and Transplantation , pp. 271-298
    • Navarro, B.1    Villa, A.2    Liste, I.3    Bueno, C.4    Martinez-Serrano, A.5
  • 46
    • 33745210285 scopus 로고    scopus 로고
    • "Is there ay need to argue..." about the nature and genetic signature of in vitro neural stem cells?
    • Navarro-Galve B., and Martinez-Serrano A. "Is there ay need to argue..." about the nature and genetic signature of in vitro neural stem cells?,. Exp. Neurol. 199 (2006) 20-25
    • (2006) Exp. Neurol. , vol.199 , pp. 20-25
    • Navarro-Galve, B.1    Martinez-Serrano, A.2
  • 47
    • 0038304477 scopus 로고    scopus 로고
    • Region-specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons
    • Hall A.C., Mira H., Wagner J., and Arenas E. Region-specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons. Glia 43 (2003) 47-51
    • (2003) Glia , vol.43 , pp. 47-51
    • Hall, A.C.1    Mira, H.2    Wagner, J.3    Arenas, E.4
  • 48
    • 33244496187 scopus 로고    scopus 로고
    • Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
    • Kele J., Simplicio N., Ferri A., Mira H., Guillemot F., Arenas E., and Ang S.L. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 133 (2006) 495-505
    • (2006) Development , vol.133 , pp. 495-505
    • Kele, J.1    Simplicio, N.2    Ferri, A.3    Mira, H.4    Guillemot, F.5    Arenas, E.6    Ang, S.L.7
  • 49
    • 33244474408 scopus 로고    scopus 로고
    • Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2
    • Andersson E., Jensen J.B., Parmar M., Guillemot F., and Bjorklund A. Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development 133 (2006) 507-516
    • (2006) Development , vol.133 , pp. 507-516
    • Andersson, E.1    Jensen, J.B.2    Parmar, M.3    Guillemot, F.4    Bjorklund, A.5
  • 50
    • 0028292347 scopus 로고
    • Mapping of the colocalization of calretinin and tyrosine hydroxylase in the rat substantia nigra and ventral tegmental area
    • Isaacs K.R., and Jacobowitz D.M. Mapping of the colocalization of calretinin and tyrosine hydroxylase in the rat substantia nigra and ventral tegmental area. Exp. Brain Res. 99 (1994) 34-42
    • (1994) Exp. Brain Res. , vol.99 , pp. 34-42
    • Isaacs, K.R.1    Jacobowitz, D.M.2
  • 51
    • 43649094851 scopus 로고    scopus 로고
    • Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3
    • Roybon L., Hjalt T., Christophersen N.S., Li J.Y., and Brundin P. Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3,. J. Neurosci. 28 (2008) 3644-3656
    • (2008) J. Neurosci. , vol.28 , pp. 3644-3656
    • Roybon, L.1    Hjalt, T.2    Christophersen, N.S.3    Li, J.Y.4    Brundin, P.5
  • 52
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., and Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007) 861-872
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 54
    • 16844364151 scopus 로고    scopus 로고
    • LIF/STAT3 controls ES cell self-renewal and pluripotency by a myc-dependent mechanism
    • Cartwright P., Mclean C., Sheppard A., Rivett D., Jones K., and Dalton S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a myc-dependent mechanism. Development 132 (2005) 885-896
    • (2005) Development , vol.132 , pp. 885-896
    • Cartwright, P.1    Mclean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 55
    • 34748919514 scopus 로고    scopus 로고
    • A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes
    • De Filippis L., Lamorte G., Snyder E.Y., Malgaroli A., and Vescovi A.L. A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes. Stem Cells 25 (2007) 2312-2321
    • (2007) Stem Cells , vol.25 , pp. 2312-2321
    • De Filippis, L.1    Lamorte, G.2    Snyder, E.Y.3    Malgaroli, A.4    Vescovi, A.L.5
  • 57
    • 43049159817 scopus 로고    scopus 로고
    • Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death
    • Alavian K.N., Scholz C., and Simon H. Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death. Mov. Dis. 23 (2007) 319-328
    • (2007) Mov. Dis. , vol.23 , pp. 319-328
    • Alavian, K.N.1    Scholz, C.2    Simon, H.3
  • 58
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow C.W., Kordower J.H., and Freeman T.B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19 (1996) 102-109
    • (1996) Trends Neurosci. , vol.19 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3


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