Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E2 production in osteoarthritic chondrocytes

Biochemical Pharmacology

Volumn 77, Issue 12, 2009, Pages 1806-1813

  Megías, Javier ^a   Guillén, María Isabel ^a,b   Clérigues, Victoria ^a   Rojo, Ana I ^c   Cuadrado, Antonio ^c   Castejón, Miguel Angel ^d   Gomar, Francisco ^a   Alcaraz, María José ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^d Hospital Universitario de la Ribera   (Spain)

Author keywords

Chondrocyte; Heme oxygenase 1; Interleukin 1 ; Microsomal PGE synthase 1; Osteoarthritis; Prostaglandin E2

Indexed keywords

AGGRECAN; CYCLOOXYGENASE 2; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; PROTOPORPHYRIN COBALT; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL ISOLATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; LASER SCANNING CYTOMETRY; OSTEOARTHRITIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; DINOPROSTONE; HEME OXYGENASE-1; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICROSOMES; OSTEOARTHRITIS; TRANSCRIPTIONAL ACTIVATION;

EID: 67349228847     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.03.009     Document Type: Article

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