GDNF-induced cell signaling and neurite outgrowths are differentially mediated by GFRalpha1 isoforms

Molecular and Cellular Neuroscience

Volumn 41, Issue 4, 2009, Pages 464-473

  Yoong, Li Foong ^a,c   Wan, Guoqiang ^a,b   Too, Heng Phon ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

GDNF; GFR 1; Inhibitory splice isoforms; Neurite outgrowth; Rho family GTPase; ROCK

Indexed keywords

CELL PROTEIN; COFILIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR FAMILY RECEPTOR ALPHA 1A; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR FAMILY RECEPTOR ALPHA 1B; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; LIM KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MYOSIN LIGHT CHAIN 2; PROTEIN CDC42; PROTEIN ROCK; RAC1 PROTEIN; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; EARLY RESPONSE GENE; ENZYME ACTIVATION; GENETIC TRANSFECTION; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CDC42 GTP-BINDING PROTEIN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM; DNA-BINDING PROTEINS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HUMANS; MICE; NEURITES; NEUROBLASTOMA; NEURTURIN; PROTEIN ISOFORMS; RAC1 GTP-BINDING PROTEIN; RHO FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 67349218425     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.05.002     Document Type: Article

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