메뉴 건너뛰기




Volumn 116, Issue 6, 2009, Pages 1175-1181

Retinal Vessel Abnormalities Are Associated with Elevated Fasting Insulin Levels and Cerebral Atrophy in Nondiabetic Individuals

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

EID: 67349189131     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2008.12.046     Document Type: Article
Times cited : (18)

References (48)
  • 1
    • 17444371697 scopus 로고    scopus 로고
    • Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures
    • Patton N., Aslam T., MacGillivray T., et al. Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures. J Anat 206 (2005) 319-348
    • (2005) J Anat , vol.206 , pp. 319-348
    • Patton, N.1    Aslam, T.2    MacGillivray, T.3
  • 2
    • 1042276731 scopus 로고    scopus 로고
    • Retinal arteriolar diameter and risk for hypertension
    • Atherosclerosis Risk in Communities Study
    • Wong T.Y., Klein R., Sharrett A.R., et al., Atherosclerosis Risk in Communities Study. Retinal arteriolar diameter and risk for hypertension. Ann Intern Med 140 (2004) 248-255
    • (2004) Ann Intern Med , vol.140 , pp. 248-255
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3
  • 3
    • 0037180475 scopus 로고    scopus 로고
    • Retinal arterial changes correlate with cerebral small-vessel disease
    • Amsterdam Vascular Medicine Group
    • Kwa V.I., van der Sande J.J., Stam J., et al., Amsterdam Vascular Medicine Group. Retinal arterial changes correlate with cerebral small-vessel disease. Neurology 59 (2002) 1536-1540
    • (2002) Neurology , vol.59 , pp. 1536-1540
    • Kwa, V.I.1    van der Sande, J.J.2    Stam, J.3
  • 4
    • 33747827858 scopus 로고    scopus 로고
    • Retinal vascular manifestations of metabolic disorders
    • Nguyen T.T., and Wong T.Y. Retinal vascular manifestations of metabolic disorders. Trends Endocrinol Metab 17 (2006) 262-268
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 262-268
    • Nguyen, T.T.1    Wong, T.Y.2
  • 5
    • 0016806331 scopus 로고
    • Pathological studies on the intracerebral and retinal arteries in cerebrovascular and noncerebrovascular diseases
    • Goto I., Katsuki S., Ikui H., et al. Pathological studies on the intracerebral and retinal arteries in cerebrovascular and noncerebrovascular diseases. Stroke 6 (1975) 263-269
    • (1975) Stroke , vol.6 , pp. 263-269
    • Goto, I.1    Katsuki, S.2    Ikui, H.3
  • 6
    • 12344264661 scopus 로고    scopus 로고
    • Insulin resistance syndrome, pre-diabetes, and the prevention of type 2 diabetes mellitus
    • Smith D.O., and LeRoith D. Insulin resistance syndrome, pre-diabetes, and the prevention of type 2 diabetes mellitus. Clin Cornerstone 6 (2004) 7-13
    • (2004) Clin Cornerstone , vol.6 , pp. 7-13
    • Smith, D.O.1    LeRoith, D.2
  • 7
    • 18344394857 scopus 로고    scopus 로고
    • Retinal arteriolar narrowing, hypertension, and subsequent risk of diabetes mellitus
    • Wong T.Y., Shankar A., Klein R., et al. Retinal arteriolar narrowing, hypertension, and subsequent risk of diabetes mellitus. Arch Intern Med 165 (2005) 1060-1065
    • (2005) Arch Intern Med , vol.165 , pp. 1060-1065
    • Wong, T.Y.1    Shankar, A.2    Klein, R.3
  • 8
    • 0037093011 scopus 로고    scopus 로고
    • Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons
    • ARIC Investigators
    • Wong T.Y., Klein R., Sharrett A.R., et al., ARIC Investigators. Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA 287 (2002) 2528-2533
    • (2002) JAMA , vol.287 , pp. 2528-2533
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3
  • 10
    • 34547227547 scopus 로고    scopus 로고
    • The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis
    • Wang Y., and Beydoun M.A. The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis. Epidemiol Rev 29 (2007) 6-28
    • (2007) Epidemiol Rev , vol.29 , pp. 6-28
    • Wang, Y.1    Beydoun, M.A.2
  • 11
    • 0027520177 scopus 로고
    • Body weight and mortality: a 27-year follow-up of middle-aged men
    • Lee I.M., Manson J.E., Hennekens C.H., and Paffenbarger Jr. R.S. Body weight and mortality: a 27-year follow-up of middle-aged men. JAMA 270 (1993) 2823-2828
    • (1993) JAMA , vol.270 , pp. 2823-2828
    • Lee, I.M.1    Manson, J.E.2    Hennekens, C.H.3    Paffenbarger Jr., R.S.4
  • 12
    • 3142616795 scopus 로고    scopus 로고
    • Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders?. The Rotterdam Study
    • Ikram M.K., de Jong F.J., Vingerling J.R., et al. Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders?. The Rotterdam Study. Invest Ophthalmol Vis Sci 45 (2004) 2129-2134
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2129-2134
    • Ikram, M.K.1    de Jong, F.J.2    Vingerling, J.R.3
  • 13
    • 31944433594 scopus 로고    scopus 로고
    • Retinal vessel diameters and risk of hypertension: the Rotterdam Study
    • Ikram M.K., Witteman J.C., Vingerling J.R., et al. Retinal vessel diameters and risk of hypertension: the Rotterdam Study. Hypertension 47 (2006) 189-194
    • (2006) Hypertension , vol.47 , pp. 189-194
    • Ikram, M.K.1    Witteman, J.C.2    Vingerling, J.R.3
  • 14
    • 34248573681 scopus 로고    scopus 로고
    • Retinal vascular signs in diabetes and hypertension-review
    • Liew G., and Wang J.J. Retinal vascular signs in diabetes and hypertension-review. Arq Bras Endocrinol Metabol 51 (2007) 352-362
    • (2007) Arq Bras Endocrinol Metabol , vol.51 , pp. 352-362
    • Liew, G.1    Wang, J.J.2
  • 15
    • 0141653763 scopus 로고    scopus 로고
    • Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people
    • Atherosclerosis Risk in Communities Study
    • Wong T.Y., Mosley Jr. T.H., Klein R., et al., Atherosclerosis Risk in Communities Study. Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people. Neurology 61 (2003) 806-811
    • (2003) Neurology , vol.61 , pp. 806-811
    • Wong, T.Y.1    Mosley Jr., T.H.2    Klein, R.3
  • 16
    • 23944518322 scopus 로고    scopus 로고
    • Dyslipidaemia and microvascular disease in the retina
    • Leung H., Wang J.J., Rochtchina E., et al. Dyslipidaemia and microvascular disease in the retina. Eye 19 (2005) 861-868
    • (2005) Eye , vol.19 , pp. 861-868
    • Leung, H.1    Wang, J.J.2    Rochtchina, E.3
  • 17
    • 0036673902 scopus 로고    scopus 로고
    • Blood pressure, lipids, and obesity are associated with retinopathy: the Hoorn study
    • van Leiden H.A., Dekker J.M., Moll A.C., et al. Blood pressure, lipids, and obesity are associated with retinopathy: the Hoorn study. Diabetes Care 25 (2002) 1320-1325
    • (2002) Diabetes Care , vol.25 , pp. 1320-1325
    • van Leiden, H.A.1    Dekker, J.M.2    Moll, A.C.3
  • 18
    • 30344460652 scopus 로고    scopus 로고
    • Are inflammatory factors related to retinal vessel caliber?. The Beaver Dam Eye Study
    • Klein R., Klein B.E., Knudtson M.D., et al. Are inflammatory factors related to retinal vessel caliber?. The Beaver Dam Eye Study. Arch Ophthalmol 124 (2006) 87-94
    • (2006) Arch Ophthalmol , vol.124 , pp. 87-94
    • Klein, R.1    Klein, B.E.2    Knudtson, M.D.3
  • 19
    • 36448943247 scopus 로고    scopus 로고
    • C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling
    • Singh U., Devaraj S., Vasquez-Vivar J., and Jialal I. C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling. J Mol Cell Cardiol 43 (2007) 780-791
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 780-791
    • Singh, U.1    Devaraj, S.2    Vasquez-Vivar, J.3    Jialal, I.4
  • 20
    • 0033529379 scopus 로고    scopus 로고
    • C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?
    • Lagrand W.K., Visser C.A., Hermens W.T., et al. C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?. Circulation 100 (1999) 96-102
    • (1999) Circulation , vol.100 , pp. 96-102
    • Lagrand, W.K.1    Visser, C.A.2    Hermens, W.T.3
  • 21
    • 0038691972 scopus 로고    scopus 로고
    • Low-grade systemic inflammation and the development of type 2 diabetes: the Atherosclerosis Risk in Communities Study
    • Duncan B.B., Schmidt M.I., Pankow J.S., et al. Low-grade systemic inflammation and the development of type 2 diabetes: the Atherosclerosis Risk in Communities Study. Diabetes 52 (2003) 1799-1805
    • (2003) Diabetes , vol.52 , pp. 1799-1805
    • Duncan, B.B.1    Schmidt, M.I.2    Pankow, J.S.3
  • 22
    • 33747867207 scopus 로고    scopus 로고
    • Retinal vessel diameters and obesity: a population-based study in older persons
    • Wang J.J., Taylor B., Wong T.Y., et al. Retinal vessel diameters and obesity: a population-based study in older persons. Obesity (Silver Spring) 14 (2006) 206-214
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 206-214
    • Wang, J.J.1    Taylor, B.2    Wong, T.Y.3
  • 23
    • 0035182026 scopus 로고    scopus 로고
    • Repeatability characteristics of simple indices of insulin resistance: implications for research applications
    • Mather K.J., Hunt A.E., Steinberg H.O., et al. Repeatability characteristics of simple indices of insulin resistance: implications for research applications. J Clin Endocrinol Metab 86 (2001) 5457-5464
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5457-5464
    • Mather, K.J.1    Hunt, A.E.2    Steinberg, H.O.3
  • 24
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 25
    • 0034485313 scopus 로고    scopus 로고
    • Insulin sensitivity and its measurement: structural commonalities among the methods
    • Radziuk J. Insulin sensitivity and its measurement: structural commonalities among the methods. J Clin Endocrinol Metab 85 (2000) 4426-4433
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4426-4433
    • Radziuk, J.1
  • 26
    • 0141427858 scopus 로고    scopus 로고
    • Revised formulas for summarizing retinal vessel diameters
    • Knudtson M.D., Lee K.E., Hubbard L.D., et al. Revised formulas for summarizing retinal vessel diameters. Curr Eye Res 27 (2003) 143-149
    • (2003) Curr Eye Res , vol.27 , pp. 143-149
    • Knudtson, M.D.1    Lee, K.E.2    Hubbard, L.D.3
  • 27
    • 2942612300 scopus 로고    scopus 로고
    • Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors
    • Wong T.Y., Knudtson M.D., Klein R., et al. Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors. Ophthalmology 111 (2004) 1183-1190
    • (2004) Ophthalmology , vol.111 , pp. 1183-1190
    • Wong, T.Y.1    Knudtson, M.D.2    Klein, R.3
  • 28
    • 0033503919 scopus 로고    scopus 로고
    • Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study
    • Atherosclerosis Risk in Communities Study Group
    • Hubbard L.D., Brothers R.J., King W.N., et al., Atherosclerosis Risk in Communities Study Group. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 106 (1999) 2269-2280
    • (1999) Ophthalmology , vol.106 , pp. 2269-2280
    • Hubbard, L.D.1    Brothers, R.J.2    King, W.N.3
  • 29
    • 0033179363 scopus 로고    scopus 로고
    • Retinal arteriolar diameters and elevated blood pressure: the Atherosclerosis Risk in Communities Study
    • Sharrett A.R., Hubbard L.D., Cooper L.S., et al. Retinal arteriolar diameters and elevated blood pressure: the Atherosclerosis Risk in Communities Study. Am J Epidemiol 150 (1999) 263-270
    • (1999) Am J Epidemiol , vol.150 , pp. 263-270
    • Sharrett, A.R.1    Hubbard, L.D.2    Cooper, L.S.3
  • 30
    • 0027339590 scopus 로고
    • A semiquantative rating scale for the assessment of signal hyperintensities on magnetic resonance imaging
    • Scheltens P., Barkhof F., Leys D., et al. A semiquantative rating scale for the assessment of signal hyperintensities on magnetic resonance imaging. J Neurol Sci 114 (1993) 7-12
    • (1993) J Neurol Sci , vol.114 , pp. 7-12
    • Scheltens, P.1    Barkhof, F.2    Leys, D.3
  • 31
    • 48249153186 scopus 로고
    • Intraclass correlations: uses in assessing rater reliability
    • Shrout P.E., and Fleiss J.L. Intraclass correlations: uses in assessing rater reliability. Psychol Bull 86 (1979) 420-428
    • (1979) Psychol Bull , vol.86 , pp. 420-428
    • Shrout, P.E.1    Fleiss, J.L.2
  • 32
    • 33847761069 scopus 로고    scopus 로고
    • Age, blood pressure, and retinal vessel diameter: separate effects and interaction of blood pressure and age
    • Kaushik S., Kifley A., Mitchell P., and Wang J.J. Age, blood pressure, and retinal vessel diameter: separate effects and interaction of blood pressure and age. Invest Ophthalmol Vis Sci 48 (2007) 557-561
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 557-561
    • Kaushik, S.1    Kifley, A.2    Mitchell, P.3    Wang, J.J.4
  • 33
    • 0037029148 scopus 로고    scopus 로고
    • Retinal arteriolar narrowing and risk of coronary heart disease in men and women: the Atherosclerosis Risk in Communities Study
    • ARIC Investigators
    • Wong T.Y., Klein R., Sharrett A.R., et al., ARIC Investigators. Retinal arteriolar narrowing and risk of coronary heart disease in men and women: the Atherosclerosis Risk in Communities Study. JAMA 287 (2002) 1153-1159
    • (2002) JAMA , vol.287 , pp. 1153-1159
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3
  • 34
    • 0034866379 scopus 로고    scopus 로고
    • Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality
    • Wong T.Y., Klein R., Klein B.E., et al. Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality. Surv Ophthalmol 46 (2001) 59-80
    • (2001) Surv Ophthalmol , vol.46 , pp. 59-80
    • Wong, T.Y.1    Klein, R.2    Klein, B.E.3
  • 35
    • 0025866122 scopus 로고
    • Are vascular abnormalities a primary cause or secondary consequence of hypertension?
    • Mulvany M.J. Are vascular abnormalities a primary cause or secondary consequence of hypertension?. Hypertension 18 suppl (1991) I52-I57
    • (1991) Hypertension , vol.18 , Issue.SUPPL
    • Mulvany, M.J.1
  • 37
    • 15044365745 scopus 로고    scopus 로고
    • Metabolic syndrome-interdependence of the cardiovascular and metabolic pathways
    • Caglayan E., Blaschke F., Takata Y., and Hsueh W.A. Metabolic syndrome-interdependence of the cardiovascular and metabolic pathways. Curr Opin Pharmacol 5 (2005) 135-142
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 135-142
    • Caglayan, E.1    Blaschke, F.2    Takata, Y.3    Hsueh, W.A.4
  • 38
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
    • Cusi K., Maezono K., Osman A., et al. Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest 105 (2000) 311-320
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3
  • 39
    • 0030007350 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Williams S.B., Cusco J.A., Roddy M.A., et al. Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 27 (1996) 567-574
    • (1996) J Am Coll Cardiol , vol.27 , pp. 567-574
    • Williams, S.B.1    Cusco, J.A.2    Roddy, M.A.3
  • 40
    • 33744917283 scopus 로고    scopus 로고
    • Increased levels of tumour necrosis factor-alpha (TNF-alpha) in patients with type II diabetes mellitus after myocardial infarction are related to endothelial dysfunction
    • Nystrom T., Nygren A., and Sjoholm A. Increased levels of tumour necrosis factor-alpha (TNF-alpha) in patients with type II diabetes mellitus after myocardial infarction are related to endothelial dysfunction. Clin Sci (Lond) 110 (2006) 673-681
    • (2006) Clin Sci (Lond) , vol.110 , pp. 673-681
    • Nystrom, T.1    Nygren, A.2    Sjoholm, A.3
  • 41
    • 33645983184 scopus 로고    scopus 로고
    • Insulin resistance/compensatory hyperinsulinemia predict carotid intimal medial thickness in patients with essential hypertension
    • Zavaroni I., Ardigo D., Zuccarelli A., et al. Insulin resistance/compensatory hyperinsulinemia predict carotid intimal medial thickness in patients with essential hypertension. Nutr Metab Cardiovasc Dis 16 (2006) 22-27
    • (2006) Nutr Metab Cardiovasc Dis , vol.16 , pp. 22-27
    • Zavaroni, I.1    Ardigo, D.2    Zuccarelli, A.3
  • 42
    • 22844435311 scopus 로고    scopus 로고
    • Insulin resistance in cognitive impairment: the InCHIANTI Study
    • Geroldi C., Frisoni G.B., Paolisso G., et al. Insulin resistance in cognitive impairment: the InCHIANTI Study. Arch Neurol 62 (2005) 1067-1072
    • (2005) Arch Neurol , vol.62 , pp. 1067-1072
    • Geroldi, C.1    Frisoni, G.B.2    Paolisso, G.3
  • 43
    • 47049129183 scopus 로고    scopus 로고
    • Glucose control levels, ischaemic brain lesions, and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly
    • Umegaki H., Kawamura T., Mogi N., et al. Glucose control levels, ischaemic brain lesions, and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly. Age Ageing 37 (2008) 458-461
    • (2008) Age Ageing , vol.37 , pp. 458-461
    • Umegaki, H.1    Kawamura, T.2    Mogi, N.3
  • 44
    • 28444485941 scopus 로고    scopus 로고
    • Links between cognitive impairment in insulin resistance: an explanatory model
    • Convit A. Links between cognitive impairment in insulin resistance: an explanatory model. Neurobiol Aging 26 suppl (2005) 31-35
    • (2005) Neurobiol Aging , vol.26 , Issue.SUPPL , pp. 31-35
    • Convit, A.1
  • 45
    • 0030884698 scopus 로고    scopus 로고
    • Insulin resistance and hypersecretion in obesity
    • European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini E., Natali A., Bell P., et al., European Group for the Study of Insulin Resistance (EGIR). Insulin resistance and hypersecretion in obesity. J Clin Invest 100 (1997) 1166-1173
    • (1997) J Clin Invest , vol.100 , pp. 1166-1173
    • Ferrannini, E.1    Natali, A.2    Bell, P.3
  • 46
    • 33847406983 scopus 로고    scopus 로고
    • Increasing trends in incidence of overweight and obesity over 5 decades
    • Parikh N.I., Pencina M.J., Wang T.J., et al. Increasing trends in incidence of overweight and obesity over 5 decades. Am J Med 120 (2007) 242-250
    • (2007) Am J Med , vol.120 , pp. 242-250
    • Parikh, N.I.1    Pencina, M.J.2    Wang, T.J.3
  • 47
    • 0345863722 scopus 로고    scopus 로고
    • Variation associated with measurement of retinal vessel diameters at different points in the pulse cycle
    • Knudtson M.D., Klein B.E., Klein R., et al. Variation associated with measurement of retinal vessel diameters at different points in the pulse cycle. Br J Ophthalmol 88 (2004) 57-61
    • (2004) Br J Ophthalmol , vol.88 , pp. 57-61
    • Knudtson, M.D.1    Klein, B.E.2    Klein, R.3
  • 48
    • 1542327237 scopus 로고    scopus 로고
    • The relation of retinal microvascular characteristics to age-related eye disease: the Beaver Dam Eye Study
    • Klein R., Klein B.E., Tomany S.C., and Wong T.Y. The relation of retinal microvascular characteristics to age-related eye disease: the Beaver Dam Eye Study. Am J Ophthalmol 137 (2004) 435-444
    • (2004) Am J Ophthalmol , vol.137 , pp. 435-444
    • Klein, R.1    Klein, B.E.2    Tomany, S.C.3    Wong, T.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.