Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia

Schizophrenia Research

Volumn 98, Issue 1-3, 2008, Pages 129-138

  Mitkus, Shruti N ^a   Hyde, Thomas M ^a   Vakkalanka, Radhakrishna ^a   Kolachana, Bhaskar ^a   Weinberger, Daniel R ^a   Kleinman, Joel E ^a   Lipska, Barbara K ^a  

^a DIRP   (United States)

Author keywords

CNP; MOBP; Myelin; OLIG2; Oligodendrocytes; Postmortem studies; Schizophrenia

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; MESSENGER RNA; MYELIN ASSOCIATED BASIC PROTEIN; MYELIN ASSOCIATED GLYCOPROTEIN; TRANSCRIPTION FACTOR IIA; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE EXPRESSION; GENETIC TRANSCRIPTION; GRAY MATTER; HIGH RISK PATIENT; HUMAN; HUMAN TISSUE; OLIGODENDROGLIA; POLYMERASE CHAIN REACTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; SUBSTANCE ABUSE; WHITE MATTER;

ADULT; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CONTROL GROUPS; FEMALE; GENE EXPRESSION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MYELIN PROTEINS; MYELIN-ASSOCIATED GLYCOPROTEIN; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; PROTEIN ARRAY ANALYSIS; RNA, MESSENGER; SCHIZOPHRENIA; VARIATION (GENETICS);

EID: 37049025403     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2007.09.032     Document Type: Article

References (38)

1. Aberg K., Saetre P., Jareborg N., and Jazin E. Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 7482-7487
2. Albertson D.N., Pruetz B., Schmidt C.J., Kuhn D.M., Kapatos G., and Bannon M.J. Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin. J. Neurochem. 88 (2004) 1211-1219
3. Aston C., Jiang L., and Sokolov B.P. Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J. Neurosci. Res. 77 (2004) 858-866
4. Covault J., Lee J., Jensen K., and Kranzler H. Nogo 3′-untranslated region CAA insertion: failure to replicate association with schizophrenia and demonstration of marked population difference in frequency of the insertion. Brain Res. Mol. Brain Res. 120 (2004) 197-200
5. Davis K.L., and Haroutunian V. Global expression-profiling studies and oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362 (2003) 758
6. Davis K.L., Stewart D.G., Friedman J.I., et al. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch. Gen. Psychiatry 60 (2003) 443-456
7. Dracheva S., Davis K.L., Chin B., Woo D.A., Schmeidler J., and Haroutunian V. Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients. Neurobiol. Dis. 21 (2006) 531-540
8. Dwork A.J., Mancevski B., and Rosoklija G. White matter and cognitive function in schizophrenia. Int. J. Neuropsychopharmacol. (2007) 1-24
9. Flynn S.W., Lang D.J., Mackay A.L., et al. Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins. Mol. Psychiatry 8 (2003) 811-820
10. Georgieva L., Moskvina V., Peirce T., et al. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 12469-12474
11. Gregorio S.P., Mury F.B., Ojopi E.B., et al. Nogo CAA 3′UTR Insertion polymorphism is not associated with Schizophrenia nor with bipolar disorder. Schizophr. Res. 75 (2005) 5-9
12. Hakak Y., Walker J.R., Li C., et al. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 4746-4751
13. Hof P.R., Haroutunian V., Friedrich Jr. V.L., et al. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol. Psychiatry 53 (2003) 1075-1085
14. Kanazawa T., Glatt S.J., Tsutsumi A., et al. Schizophrenia is not associated with the functional candidate gene ERBB3: results from a case-control study. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 144 (2007) 113-116
15. Katsel P., Davis K.L., and Haroutunian V. Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study. Schizophr. Res. 79 (2005) 157-173
16. Kubicki M., McCarley R.W., and Shenton M.E. Evidence for white matter abnormalities in schizophrenia. Curr. Opin. Psychiatry 18 (2005) 121-134
17. Lipska B.K., Deep-Soboslay A., Weickert C.S., et al. Critical factors in gene expression in postmortem human brain: focus on studies in schizophrenia. Biol. Psychiatry 60 (2006) 650-658
18. Liu J., Lewohl J.M., Dodd P.R., Randall P.K., Harris R.A., and Mayfield R.D. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. J. Neurochem. 90 (2004) 1050-1058
19. Liu X., Qin W., He G., et al. A family-based association study of the MOG gene with schizophrenia in the Chinese population. Schizophr. Res. 73 (2005) 275-280
20. McCullumsmith R.E., Gupta D., Beneyto M., et al. Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia. Schizophr. Res. 90 (2007) 15-27
21. McInnes L.A., and Lauriat T.L. RNA metabolism and dysmyelination in schizophrenia. Neurosci. Biobehav. Rev. 30 (2006) 551-561
22. Nackley A.G., Shabalina S.A., Tchivileva I.E., et al. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 314 (2006) 1930-1933
23. Narayan S., Kass K.E., and Thomas E.A. Chronic haloperidol treatment results in a decrease in the expression of myelin/oligodendrocyte-related genes in the mouse brain. J. Neurosci. Res. 85 (2007) 757-765
24. Novak G., and Tallerico T. Nogo A, B and C expression in schizophrenia, depression and bipolar frontal cortex, and correlation of Nogo expression with CAA/TATC polymorphism in 3′-UTR. Brain. Res. 1120 (2006) 161-171
25. Peirce T.R., Bray N.J., Williams N.M., et al. Convergent evidence for 2′,3′-cyclic nucleotide 3′-phosphodiesterase as a possible susceptibility gene for schizophrenia. Arch. Gen. Psychiatry 63 (2006) 18-24
26. Prabakaran S., Swatton J.E., Ryan M.M., et al., (2004): Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 9:684-697, 643.
27. Qin W., Gao J., Xing Q., et al. A family-based association study of PLP1 and schizophrenia. Neurosci. Lett. 375 (2005) 207-210
28. Rajkowska G., and Goldman-Rakic P.S. Cytoarchitectonic definition of prefrontal areas in the normal human cortex: II. Variability in locations of areas 9 and 46 and relationship to the Talairach Coordinate System. Cereb. Cortex 5 (1995) 323-337
29. Tan E.C., Chong S.A., Wang H., Chew-Ping Lim E., and Teo Y.Y. Gender-specific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophrenia. Brain Res. Mol. Brain Res. 139 (2005) 212-216
30. Tang F., Qu M., Wang L., et al. Case-control association study of the 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNP) gene and schizophrenia in the Han Chinese population. Neurosci. Lett. 416 (2007) 113-116
31. Thompson P.M., Hayashi K.M., Simon S.L., et al. Structural abnormalities in the brains of human subjects who use methamphetamine. J. Neurosci. 24 (2004) 6028-6036
32. Tkachev D., Mimmack M.L., Ryan M.M., et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362 (2003) 798-805
33. Usui H., Takahashi N., Saito S., et al. The 2′,3′-cyclic nucleotide 3′-phosphodiesterase and oligodendrocyte lineage transcription factor 2 genes do not appear to be associated with schizophrenia in the Japanese population. Schizophr. Res. 88 (2006) 245-250
34. Wan C., Yang Y., Feng G., et al. Polymorphisms of myelin-associated glycoprotein gene are associated with schizophrenia in the Chinese Han population. Neurosci. Lett. 388 (2005) 126-131
35. Watanabe Y., Fukui N., Nunokawa A., et al. No association between the ERBB3 gene and schizophrenia in a Japanese population. Neurosci. Res. 57 (2007) 574-578
36. Xiong L., Rouleau G.A., Delisi L.E., et al. CAA insertion polymorphism in the 3′UTR of Nogo gene on 2p14 is not associated with schizophrenia. Brain Res. Mol. Brain Res. 133 (2005) 153-156
37. Yang Y.F., Qin W., Shugart Y.Y., et al. Possible association of the MAG locus with schizophrenia in a Chinese Han cohort of family trios. Schizophr. Res. 75 (2005) 11-19
38. Zai G., King N., Wigg K., et al. Genetic study of the myelin oligodendrocyte glycoprotein (MOG) gene in schizophrenia. Genes Brain Behav. 4 (2005) 2-9