Naphtho[2,3-d]isoxazole-4,9-dione-3-carboxylates: Potent, non-cytotoxic, antiapoptotic agents

Chemico-Biological Interactions

Volumn 180, Issue 2, 2009, Pages 175-182

  Santos, Daniela M ^a   Santos, Maria M M ^a   Viana, Ricardo J S ^a   Castro, Rui E ^a   Moreira, Rui ^a   Rodrigues, Cecília M P ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Apoptosis; Bcl XL; Caspases; Hepatocytes; Naphthoquinone derivatives

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; NAPHTHO[2,3 D]ISOXAZOLE 4,9 DIONE 3 CARBOXYLATE DERIVATIVE; PROTEIN BCL XL; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME RELEASE; LIVER CELL; NONHUMAN; RAT;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CAMPTOTHECIN; CYTOCHROMES C; CYTOPROTECTION; GENE EXPRESSION REGULATION; HEPATOCYTES; MOLECULAR STRUCTURE; NAPHTHOQUINONES; RATS;

RATTUS;

EID: 67349174541     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.03.007     Document Type: Article

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