The Bsmoc group as a novel scaffold for the design of irreversible inhibitors of cysteine proteases

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 10, 2006, Pages 2738-2741

  Iley, Jim ^a   Moreira, Rui ^b   Martins, Luísa ^b   Guedes, Rita C ^b   Soares, Cláudio M ^c  

^a OPEN UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LISBON   (Portugal)

^c INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

Bsmoc; Cathepsin B; Cysteine proteases; Papain

Indexed keywords

CARBAMIC ACID; CARBAMIC ACID DERIVATIVE; CARBOXYLIC ACID; CATHEPSIN B; CYSTEINE PROTEINASE INHIBITOR; ESTER DERIVATIVE; LIVER ENZYME; PANCREATIC ELASTASE; PAPAIN; SERINE PROTEINASE; THIOL DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; MICHAEL ADDITION; SWINE;

SUIDAE; SUS SCROFA;

EID: 33645857658     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.007     Document Type: Article

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