CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells

Nature Biotechnology

Volumn 24, Issue 3, 2006, Pages 351-357

  Herszfeld, Daniella ^a   Wolvetang, Ernst ^a   Langton Bunker, Emma ^a   Chung, Tung Liang ^a   Filipczyk, Adam A ^a   Houssami, Souheir ^a   Jamshidi, Pegah ^a   Koh, Karen ^a   Laslett, Andrew L ^a   Michalska, Anna ^a   Nguyen, Linh ^a   Reubinoff, Benjamin E ^a,d   Tellis, Irene ^a   Auerbach, Jonathan M ^b   Ording, Carol J ^b   Looijenga, Leendert H J ^c   Pera, Martin F ^a  

^a MONASH UNIVERSITY   (Australia)

^b Stem Cell Center   (United States)

^c JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^d HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; QUALITY CONTROL; TUMORS;

GENETIC LESIONS; HUMAN EMBRYONIC STEM (HES); TUMOR NECROSIS FACTOR;

CELL CULTURE;

BIOLOGICAL MARKER; CD30 ANTIGEN; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL TRANSFORMATION; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; CYTOGENETICS; EMBRYONIC STEM CELL; GENE AMPLIFICATION; GENE DELETION; GENETIC IDENTIFICATION; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FAMILY;

ANTIGENS, CD30; BIOLOGICAL MARKERS; CARCINOMA, EMBRYONAL; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; HUMANS; IMMUNOHISTOCHEMISTRY; KARYOTYPING; PLURIPOTENT STEM CELLS;

EID: 33644858065     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1197     Document Type: Article

References (30)

1. Draper, J.S. et al. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat. Biotechnol. 22, 53-54 (2004).
2. Cowan, C.A. et al. Derivation of embryonic stem-cell lines from human blastocysts. N. Engl. J. Med. 350, 1353-1356 (2004).
3. Zeng, X. et al. BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation. Restor. Neurol. Neurosci. 22, 421-428 (2004).
4. Maitra, A. et al. Genomic alterations in cultured human embryonic stem cells. Nat. Genet. 37, 1099-1103 (2005).
5. Durkop, H. et al. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 68, 421-427 (1992).
6. Horie, R. & Watanabe, T. CD30: expression and function in health and disease. Semin. Immunol. 10, 457-470 (1998).
7. Durkop, H. et al. Expression of the CD30 antigen in non-lymphoid tissues and cells. J. Pathol. 190, 613-618 (2000).
8. Pera, M.F., Bennett, W. & Cerretti, D.P. Expression of CD30 and CD30 ligand in cultured cell lines from human germ-cell tumors. Lab. Invest. 76, 497-504 (1997).
9. Horie, R. et al. A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages. Blood 88, 2422-2432 (1996).
10. Croager, E.J., Gout, A.M. & Abraham, L.J. Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene. Am. J. Pathol. 156, 1723-1731 (2000).
11. Amit, M. et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev. Biol. 227, 271-278 (2000).
12. Xu, C. et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat. Biotechnol. 19, 971-974 (2001).
13. Oosterhuis, J.W. & Looijenga, L.H. Testicular germ-cell tumours in a broader perspective. Nat. Rev. Cancer 5, 210-222 (2005).
14. Henegariu, O. et al. Characterization of gains, losses, and regional amplification in testicular germ cell tumor cell lines by comparative genomic hybridization. Cancer Genet. Cytogenet. 148, 14-20 (2004).
15. Pallesen, G. & Hamilton-Dutoit, S.J. Ki-1 (CD30) antigen is regularly expressed by tumor cells of embryonal carcinoma. Am. J. Pathol. 133, 446-450 (1988).
16. Pera, M.F., Bennett, W. & Cerretti, D.P. CD30 and its ligand: possible role in regulation of teratoma stem cells. APMIS 106, 169-173 (1998).
17. Amakawa, R. et al. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice. Cell 84, 551-562 (1996).
18. Reubinoff, B.E., Pera, M.F., Fong, C.Y., Trounson, A. & Bongso, A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18, 399-404 (2000).
19. Thomson, J.A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
20. Buzzard, J.J., Gough, N.M., Crook, J.M. & Colman, A. Karyotype of human ES cells during extended culture. Nat. Biotechnol. 22, 381-382, author reply, 382 (2004).
21. Pera, M.F., Cooper, S., Mills, J. & Parrington, J.M. Isolation and characterization of a multipotent clone of human embryonal carcinoma cells. Differentiation 42, 10-23 (1989).
22. Kadin, M.E. Regulation of CD30 antigen expression and its potential significance for human disease. Am. J. Pathol. 156, 1479-1484 (2000).
23. Enver, T. et al. Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells. Hum. Mol. Genet. 14, 3129-3140 (2005).
24. Andrews, P.W. et al. The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research. Nat. Biotechnol. 23, 795-797 (2005).
25. Doronina, S.O. et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat. Biotechnol. 21, 778-784 (2003).
26. Pera, M.F., Blasco Lafita, M.J. & Mills, J. Cultured stem-cells from human testicular teratomas: the nature of human embryonal carcinoma, and its comparison with two types of yolk-sac carcinoma. Int. J. Cancer 40, 334-343 (1987).
27. Herszfeld, D. & Pera, M.F. Differentiation of human pluripotent teratocarcinoma cells induced by bone morphogenetic protein-2. Reprod. Fertil. Dev. 10, 551-555 (1998).
28. Pera, M.F. et al. Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin. J. Cell Sci. 117, 1269-1280 (2004).
29. Roach, S., Schmid, W. & Pera, M.F. Hepatocytic transcription factor expression in human embryonal carcinoma and yolk sac carcinoma cell lines: expression of HNR-3α in models of early endodermal cell differentiation. Exp. Cell Res. 215, 189-198 (1994).
30. Pera, M.F., Filipczyk, A.A., Hawes, S.M. & Laslett, A.L. Isolation, characterization, and differentiation of human embryonic stem cells. Methods Enzymol. 365, 429-446 (2003).