-
1
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
-
(2005)
Nature
, vol.438
, pp. 932-936
-
-
Carmeliet, P.1
-
2
-
-
0038376002
-
Molecular regulation of vessel maturation
-
Jain R.K. Molecular regulation of vessel maturation. Nat. Med. 9 (2003) 685-693
-
(2003)
Nat. Med.
, vol.9
, pp. 685-693
-
-
Jain, R.K.1
-
3
-
-
0033233243
-
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
-
Semenza G.L. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15 (1999) 551-578
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
4
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat. Rev., Cancer 3 (2003) 721-732
-
(2003)
Nat. Rev., Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
5
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D., Itin A., Soffer D., and Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359 (1992) 843-845
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
6
-
-
44149092895
-
Hypoxia in prostate cancer: a powerful shield against tumour destruction?
-
Marignol L., Coffey M., Lawler M., and Hollywood D. Hypoxia in prostate cancer: a powerful shield against tumour destruction?. Cancer Treat. Rev. 34 (2008) 313-327
-
(2008)
Cancer Treat. Rev.
, vol.34
, pp. 313-327
-
-
Marignol, L.1
Coffey, M.2
Lawler, M.3
Hollywood, D.4
-
7
-
-
0026781869
-
Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms
-
Kao J., Ryan J., Brett G., Chen J., Shen H., Fan Y.G., Godman G., Familletti P.C., Wang F., Pan Y.C., Stern D., and Clauss M. Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms. J. Biol. Chem. 267 (1992) 20239-20247
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20239-20247
-
-
Kao, J.1
Ryan, J.2
Brett, G.3
Chen, J.4
Shen, H.5
Fan, Y.G.6
Godman, G.7
Familletti, P.C.8
Wang, F.9
Pan, Y.C.10
Stern, D.11
Clauss, M.12
-
8
-
-
0033947124
-
Endothelial monocyte activating polypeptide II induces endothelial cell apoptosis and may inhibit tumor angiogenesis
-
Berger A.C., Alexander H.R., Tang G., Wu P.S., Hewitt S.M., Turner E., Kruger E., Figg W.D., Grove A., Kohn E., Stern D., and Libutti S.K. Endothelial monocyte activating polypeptide II induces endothelial cell apoptosis and may inhibit tumor angiogenesis. Microvasc. Res. 60 (2000) 70-80
-
(2000)
Microvasc. Res.
, vol.60
, pp. 70-80
-
-
Berger, A.C.1
Alexander, H.R.2
Tang, G.3
Wu, P.S.4
Hewitt, S.M.5
Turner, E.6
Kruger, E.7
Figg, W.D.8
Grove, A.9
Kohn, E.10
Stern, D.11
Libutti, S.K.12
-
9
-
-
0343962297
-
Tumour necrosis factor receptor I (p55) is upregulated on endothelial cells by exposure to the tumour-derived cytokine endothelial monocyte-activating polypeptide II (EMAP-II)
-
Berger A.C., Alexander H.R., Wu P.C., Tang G., Gnant M.F., Mixon A., Turner E.S., and Libutti S.K. Tumour necrosis factor receptor I (p55) is upregulated on endothelial cells by exposure to the tumour-derived cytokine endothelial monocyte-activating polypeptide II (EMAP-II). Cytokine 12 (2000) 992-1000
-
(2000)
Cytokine
, vol.12
, pp. 992-1000
-
-
Berger, A.C.1
Alexander, H.R.2
Wu, P.C.3
Tang, G.4
Gnant, M.F.5
Mixon, A.6
Turner, E.S.7
Libutti, S.K.8
-
10
-
-
33749995841
-
Endothelial monocyte-activating polypeptide-II and its functions in (patho)physiological processes
-
van Horssen R., Eggermont A.M., and ten Hagen T.L. Endothelial monocyte-activating polypeptide-II and its functions in (patho)physiological processes. Cytokine Growth Factor Rev. 17 (2006) 339-348
-
(2006)
Cytokine Growth Factor Rev.
, vol.17
, pp. 339-348
-
-
van Horssen, R.1
Eggermont, A.M.2
ten Hagen, T.L.3
-
11
-
-
0033567895
-
Sensitization of tumor necrosis factor alpha-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus
-
Gnant M.F., Berger A.C., Huang J., Puhlmann M., Wu P.C., Merino M.J., Bartlett D.L., Alexander Jr. H.R., and Libutti S.K. Sensitization of tumor necrosis factor alpha-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus. Cancer Res. 59 (1999) 4668-4674
-
(1999)
Cancer Res.
, vol.59
, pp. 4668-4674
-
-
Gnant, M.F.1
Berger, A.C.2
Huang, J.3
Puhlmann, M.4
Wu, P.C.5
Merino, M.J.6
Bartlett, D.L.7
Alexander Jr., H.R.8
Libutti, S.K.9
-
12
-
-
39449095721
-
Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha
-
Crippa L., Gasparri A., Sacchi A., Ferrero E., Curnis F., and Corti A. Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha. Cancer Res. 68 (2008) 1154-1161
-
(2008)
Cancer Res.
, vol.68
, pp. 1154-1161
-
-
Crippa, L.1
Gasparri, A.2
Sacchi, A.3
Ferrero, E.4
Curnis, F.5
Corti, A.6
-
13
-
-
33747450862
-
Intratumoural expression of TNF-R1 and EMAP-II in relation to response of patients treated with TNF-based isolated limb perfusion
-
van Horssen R., Rens J.A., Brunstein F., Guns V., van Gils M., Hagen T.L., and Eggermont A.M. Intratumoural expression of TNF-R1 and EMAP-II in relation to response of patients treated with TNF-based isolated limb perfusion. Int. J. Cancer 119 (2006) 1481-1490
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1481-1490
-
-
van Horssen, R.1
Rens, J.A.2
Brunstein, F.3
Guns, V.4
van Gils, M.5
Hagen, T.L.6
Eggermont, A.M.7
-
14
-
-
20344377898
-
Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells
-
Tandle A.T., Mazzanti C., Alexander H.R., Roberts D.D., and Libutti S.K. Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells. Cytokine 30 (2005) 347-358
-
(2005)
Cytokine
, vol.30
, pp. 347-358
-
-
Tandle, A.T.1
Mazzanti, C.2
Alexander, H.R.3
Roberts, D.D.4
Libutti, S.K.5
-
15
-
-
13944276440
-
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha
-
Baek J.H., Mahon P.C., Oh J., Kelly B., Krishnamachary B., Pearson M., Chan D.A., Giaccia A.J., and Semenza G.L. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Mol. Cell 17 (2005) 503-512
-
(2005)
Mol. Cell
, vol.17
, pp. 503-512
-
-
Baek, J.H.1
Mahon, P.C.2
Oh, J.3
Kelly, B.4
Krishnamachary, B.5
Pearson, M.6
Chan, D.A.7
Giaccia, A.J.8
Semenza, G.L.9
-
16
-
-
0037040963
-
Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation
-
Chang S.Y., Park S.G., Kim S., and Kang C.Y. Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation. J. Biol. Chem. 277 (2002) 8388-8394
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8388-8394
-
-
Chang, S.Y.1
Park, S.G.2
Kim, S.3
Kang, C.Y.4
-
17
-
-
0036682284
-
Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway
-
Rapisarda A., Uranchimeg B., Scudiero D.A., Selby M., Sausville E.A., Shoemaker R.H., and Melillo G. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 62 (2002) 4316-4324
-
(2002)
Cancer Res.
, vol.62
, pp. 4316-4324
-
-
Rapisarda, A.1
Uranchimeg, B.2
Scudiero, D.A.3
Selby, M.4
Sausville, E.A.5
Shoemaker, R.H.6
Melillo, G.7
-
18
-
-
33645504221
-
Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells
-
Calvani M., Rapisarda A., Uranchimeg B., Shoemaker R.H., and Melillo G. Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells. Blood 107 (2006) 2705-2712
-
(2006)
Blood
, vol.107
, pp. 2705-2712
-
-
Calvani, M.1
Rapisarda, A.2
Uranchimeg, B.3
Shoemaker, R.H.4
Melillo, G.5
-
19
-
-
27744436481
-
Endothelial-monocyte activating polypeptide II alters fibronectin based endothelial cell adhesion and matrix assembly via alpha5 beta1 integrin
-
Schwarz M.A., Zheng H., Liu J., Corbett S., and Schwarz R.E. Endothelial-monocyte activating polypeptide II alters fibronectin based endothelial cell adhesion and matrix assembly via alpha5 beta1 integrin. Exp. Cell Res. 311 (2005) 229-239
-
(2005)
Exp. Cell Res.
, vol.311
, pp. 229-239
-
-
Schwarz, M.A.1
Zheng, H.2
Liu, J.3
Corbett, S.4
Schwarz, R.E.5
-
20
-
-
0035370123
-
Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7
-
Cho S., Choi Y.J., Kim J.M., Jeong S.T., Kim J.H., Kim S.H., and Ryu S.E. Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7. FEBS Lett. 498 (2001) 62-66
-
(2001)
FEBS Lett.
, vol.498
, pp. 62-66
-
-
Cho, S.1
Choi, Y.J.2
Kim, J.M.3
Jeong, S.T.4
Kim, J.H.5
Kim, S.H.6
Ryu, S.E.7
-
21
-
-
4444257379
-
The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease
-
Giaccia A.J., Simon M.C., and Johnson R. The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease. Genes Dev. 18 (2004) 2183-2194
-
(2004)
Genes Dev.
, vol.18
, pp. 2183-2194
-
-
Giaccia, A.J.1
Simon, M.C.2
Johnson, R.3
-
22
-
-
33745138232
-
Regulation of angiogenesis by hypoxia-inducible factor 1
-
Hirota K., and Semenza G.L. Regulation of angiogenesis by hypoxia-inducible factor 1. Crit. Rev. Oncol./Hematol. 59 (2006) 15-26
-
(2006)
Crit. Rev. Oncol./Hematol.
, vol.59
, pp. 15-26
-
-
Hirota, K.1
Semenza, G.L.2
-
23
-
-
0035983579
-
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies
-
Francis S.E., Goh K.L., Hodivala-Dilke K., Bader B.L., Stark M., Davidson D., and Hynes R.O. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 927-933
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 927-933
-
-
Francis, S.E.1
Goh, K.L.2
Hodivala-Dilke, K.3
Bader, B.L.4
Stark, M.5
Davidson, D.6
Hynes, R.O.7
-
24
-
-
0034604650
-
Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties
-
Maeshima Y., Colorado P.C., and Kalluri R. Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. J. Biol. Chem. 275 (2000) 23745-23750
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23745-23750
-
-
Maeshima, Y.1
Colorado, P.C.2
Kalluri, R.3
-
25
-
-
0037446897
-
Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins
-
Sudhakar A., Sugimoto H., Yang C., Lively J., Zeisberg M., and Kalluri R. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 4766-4771
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 4766-4771
-
-
Sudhakar, A.1
Sugimoto, H.2
Yang, C.3
Lively, J.4
Zeisberg, M.5
Kalluri, R.6
-
26
-
-
12844269776
-
Fibronectin matrix turnover occurs through a caveolin-1-dependent process
-
Sottile J., and Chandler J. Fibronectin matrix turnover occurs through a caveolin-1-dependent process. Mol. Biol. Cell 16 (2005) 757-768
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 757-768
-
-
Sottile, J.1
Chandler, J.2
-
27
-
-
49649095969
-
Caveolin-1-dependent {beta}1 integrin endocytosis is a critical regulator of fibronectin turnover
-
Shi F., and Sottile J. Caveolin-1-dependent {beta}1 integrin endocytosis is a critical regulator of fibronectin turnover. J. Cell. Sci. 121 (2008) 2360-2371
-
(2008)
J. Cell. Sci.
, vol.121
, pp. 2360-2371
-
-
Shi, F.1
Sottile, J.2
-
29
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., and Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
30
-
-
0033525830
-
Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway
-
Kallio P.J., Wilson W.J., O Brien S., Makino Y., and Poellinger L. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. J. Biol. Chem. 274 (1999) 6519-6525
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6519-6525
-
-
Kallio, P.J.1
Wilson, W.J.2
O Brien, S.3
Makino, Y.4
Poellinger, L.5
-
31
-
-
0034712939
-
Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
-
Sutter C.H., Laughner E., and Semenza G.L. Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 4748-4753
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 4748-4753
-
-
Sutter, C.H.1
Laughner, E.2
Semenza, G.L.3
-
32
-
-
0033517112
-
Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells
-
Schwarz M.A., Kandel J., Brett J., Li J., Hayward J., Schwarz R.E., Chappey O., Wautier J.L., Chabot J., Lo Gerfo P., and Stern D. Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells. J. Exp. Med. 190 (1999) 341-354
-
(1999)
J. Exp. Med.
, vol.190
, pp. 341-354
-
-
Schwarz, M.A.1
Kandel, J.2
Brett, J.3
Li, J.4
Hayward, J.5
Schwarz, R.E.6
Chappey, O.7
Wautier, J.L.8
Chabot, J.9
Lo Gerfo, P.10
Stern, D.11
-
33
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D., and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86 (1996) 353-364
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
34
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H., De Marzo A.M., Laughner E., Lim M., Hilton D.A., Zagzag D., Buechler P., Isaacs W.B., Semenza G.L., and Simons J.W. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 59 (1999) 5830-5835
-
(1999)
Cancer Res.
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
35
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe J.A., Jiang B.H., Iyer N.V., Agani F., Leung S.W., Koos R.D., and Semenza G.L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16 (1996) 4604-4613
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
36
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
Manalo D.J., Rowan A., Lavoie T., Natarajan L., Kelly B.D., Ye S.Q., Garcia J.G., and Semenza G.L. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105 (2005) 659-669
-
(2005)
Blood
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
37
-
-
7944224442
-
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
-
Tang N., Wang L., Esko J., Giordano F.J., Huang Y., Gerber H.P., Ferrara N., and Johnson R.S. Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 6 (2004) 485-495
-
(2004)
Cancer Cell
, vol.6
, pp. 485-495
-
-
Tang, N.1
Wang, L.2
Esko, J.3
Giordano, F.J.4
Huang, Y.5
Gerber, H.P.6
Ferrara, N.7
Johnson, R.S.8
-
38
-
-
33749362031
-
Inhibiting hypoxia-inducible factor 1 for cancer therapy
-
Melillo G. Inhibiting hypoxia-inducible factor 1 for cancer therapy. Mol. Cancer Res. 4 (2006) 601-605
-
(2006)
Mol. Cancer Res.
, vol.4
, pp. 601-605
-
-
Melillo, G.1
|