Expression of BHRF1 improves survival of murine hybridoma cultures in batch and continuous modes

Applied Microbiology and Biotechnology

Volumn 83, Issue 1, 2009, Pages 43-57

  Juanola, Sandra ^a   Vives, Joaquim ^a   Milián, Ernest ^a   Prats, Eva ^b   Cairó, Jordi J ^a   Gòdia, Francesc ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

Apoptosis protection; BHRF1; Hybridoma cells

Indexed keywords

ANTI-APOPTOTIC EFFECTS; ANTI-APOPTOTIC PROTEINS; APOPTOSIS PROTECTION; BHRF1; BICISTRONIC; BIOTECHNOLOGICAL PROCESS; CELL LINES; CELL-CYCLE ARRESTS; CONTINUOUS CULTURES; CONTINUOUS MODES; DEAD CELLS; EPSTEIN-BARR VIRUS; HIGH CELL DENSITIES; HYBRIDOMA CELLS; LIFE SPANS; MECHANISM OF ACTIONS; OVER EXPRESSIONS; PERFUSION CULTURES; POTENTIAL APPLICATIONS; PROTECTIVE EFFECTS; SELECTIVE PRESSURES; SEMI-CONTINUOUS; SPECIFIC PRODUCTIVITIES;

AMINO ACIDS; ANIMAL CELL CULTURE; BIOCHEMISTRY; CELL DEATH; CELL GROWTH; CHEMICAL REACTORS; GENETIC ENGINEERING; MONOCLONAL ANTIBODIES; PRESSURE EFFECTS; PROCESS ENGINEERING;

CELL CULTURE;

BAMHI RIGHTWARD READING FRAME 1 PROTEIN; GLUTAMINE; PROTEIN BCL 2; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID; APOPTOSIS; BIOREACTOR; BIOTECHNOLOGY; GENE EXPRESSION; GROWTH RATE; HOMOLOGY; PROTEIN; STARVATION; SURVIVAL; VIRUS;

ANIMAL CELL; APOPTOSIS; ARTICLE; BATCH CELL CULTURE; BIOTECHNOLOGICAL PROCEDURES; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL DENSITY; CELL PROTECTION; CONTINUOUS CULTURE; CONTROLLED STUDY; EPSTEIN BARR VIRUS; GENE OVEREXPRESSION; HYBRIDOMA CELL CULTURE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURAL HOMOLOGY;

ANIMALS; APOPTOSIS; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; HYBRIDOMAS; MICE; MODELS, BIOLOGICAL; VIRAL PROTEINS;

ANIMALIA; HUMAN HERPESVIRUS 4; MURINAE;

EID: 67349105315     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-008-1820-8     Document Type: Article

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