Neurotoxic effect of 2,5-hexanedione on neural progenitor cells and hippocampal neurogenesis

Toxicology

Volumn 260, Issue 1-3, 2009, Pages 97-103

  Kim, Min Sun ^a   Park, Hee Ra ^a   Park, Mikyung ^a   Kim, So Jung ^a   Kwon, Mugil ^b   Yu, Byung Pal ^c   Chung, Hae Young ^a   Kim, Hyung Sik ^a   Kwack, Seung Jun ^d   Kang, Tae Seok ^d   Kim, Seung Hee ^d   Lee, Jaewon ^a  

^a Pusan National University   (South Korea)

^b Kunwha Pharmaceutical Co Ltd   (South Korea)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d Korea Food and Drug Administration   (South Korea)

Author keywords

2,5 Hexanedione; Hippocampal neurogenesis; Neural progenitor cells

Indexed keywords

ACETONYLACETONE; BROXURIDINE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DENTATE GYRUS; EMBRYO; ENZYME ACTIVATION; HIPPOCAMPUS; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROTOXICITY; NEWBORN; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSORIMOTOR NEUROPATHY; TREATMENT DURATION; TREATMENT OUTCOME;

ANIMALS; CELL GROWTH PROCESSES; CELL LINE; CELL SURVIVAL; HEXANONES; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LACTIC ACID; MALE; MICE; MICE, INBRED ICR; NEUROGENESIS; NEURONS; OXIDATIVE STRESS; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; STEM CELLS;

ANIMALIA; MURINAE; MUS;

EID: 67349096841     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.03.013     Document Type: Article

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