Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades

Clinical Immunology

Volumn 131, Issue 3, 2009, Pages 481-494

  Yan, Xiao jie ^a   Qi, Mei ^a   Telusma, Gloria ^a   Yancopoulos, Sophia ^a   Madaio, Michael ^b   Satoh, Minoru ^c   Reeves, Westley H ^c   Teichberg, Saul ^a   Kohn, Nina ^a   Auborn, Karen ^a,d   Chiorazzi, Nicholas ^a,d,e  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Autoantibodies; B lymphocytes; Cytokines; Estrogen; I3C; Lymphocyte maturation; Renal disease; SLE; Systemic lupus erythematosus; T lymphocytes

Indexed keywords

3 INDOLEMETHANOL; AUTOANTIBODY; CONCANAVALIN A; CYTOKINE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2B ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; MITOGENIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIET SUPPLEMENTATION; DISEASE COURSE; DRUG EFFECT; DRUG MECHANISM; ELECTRON MICROSCOPY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; KIDNEY DISEASE; KIDNEY FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; SEROLOGY; STATISTICAL ANALYSIS; SURVIVAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTICARCINOGENIC AGENTS; AUTOANTIBODIES; B-LYMPHOCYTES; CELL DIFFERENTIATION; CYTOKINES; DISEASE MODELS, ANIMAL; ESTROGENS; FEMALE; IMMUNOGLOBULIN G; INDOLES; KAPLAN-MEIERS ESTIMATE; LONGITUDINAL STUDIES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; NEPHRITIS; T-LYMPHOCYTE SUBSETS;

EID: 67349084644     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.01.013     Document Type: Article

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