The relationship between Th1/Th2-type cells and disease activity in patients with systemic lupus erythematosus

Chinese Medical Journal

Volumn 113, Issue 10, 2000, Pages 877-880

  Chen, Shunle ^a   Hu, Dawei ^a   Shi, Xuegeng ^b   Shen, Nan ^a   Gu, Yueying ^a   Bao, Chunde ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cytokine; Flow cytometry; Systemic lupus erythematosus; Th1 cells; Th2 cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4;

ADULT; ARTICLE; BIOSYNTHESIS; CELL CULTURE; FEMALE; HUMAN; IMMUNOLOGY; MALE; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL; TH2 CELL;

ADULT; CELLS, CULTURED; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; TH1 CELLS; TH2 CELLS;

EID: 0034308910     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Kotzin BL. Systemic lupus erythematosus. Cell 1996;85:303-306.
2. Steinberg AD. Insight into the basis of systemic lupus. J Autoimmun 1995;8:771-775.
3. al-Janadi M, Raziuddin S. B cell hyperactivity is a function of T-cell-derived cytokines in systemic lupus erythematosus. J Rheumatol 1993;20:1888-1891.
4. Steinberg AD, Gourley MF, Klinman DM, et al. Systemic lupus erythematosus. Ann Intern Med 1991;115:548-559.
5. Hagiwara E, Gourley MF, Lee S, et al. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10: interferon-γ-secreting cells in the peripheral blood. Arthritis Rheum 1996;39:379-385.
6. Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4 Ig. Science 1994;265:1225-1227.
7. Horwitz DA, Gray JD, Behrendsen SB, et al. Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum 1998;41:838-844.
8. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-1277.
9. Bombardier CB, Gladman DD, Urowitz MB. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 1992;35:630-640.
10. Prussin C, Metcalfe. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 1995;188:117-128.
11. Sewell WA, North ME, David A, et al. Determination of intracellular cytokines by flow-cytometry following whole-blood culture. J Immunol Methods 1997;209:67-74.
12. Carter LL, Swain SL. Single cell analyses of cytokine production. Curr Opin Immunol 1997;9:177-182.
13. Ogawa N, Itoh M, Goto Y. Abnormal production of B cell growth factor in patients with systemic lupus erythematosus. Clin Exp Immunol 1992;89:26-31.
14. al-Janadi M, al-Balla S, al-Dalaan A, et al. Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases. J Clin Immunol 1993;13:58-67.
15. Funauchi M, Ikoma S, Enomoto H, et al. Decreased Th1-like and increased Th2-like cells in systemic lupus erythematosus. Scand J Rheumatol 1998;27:219-224.
16. Lauwerys BR, Houssiaau FA. Cytokine: clues to the pathogenesis of SLE. Lupus 1998;7:211-213.
17. Liorente L, Richauu-Patin Y, Couderl J, et al. Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus. Arthritis Rheum 1997;40:1429-1435.