A general method to design dominant negatives to B-HLHZip proteins that abolish DNA binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 23, 1997, Pages 12274-12279

  Krylov, Dmitry ^a   Kasai, Kenji ^b   Echlin, Deborah R ^c   Taparowsky, Elizabeth J ^c   Arnheiter, Heinz ^b   Vinson, Charles ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Heterodimer; Max; Mitf; Myc; Protein design; Transcription factor enhancer binding

Indexed keywords

HELIX LOOP HELIX PROTEIN; LEUCINE ZIPPER PROTEIN; ONCOPROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; DIMERIZATION; DNA BINDING; FIBROBLAST; MOUSE; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION;

AMINO ACID SEQUENCE; DIMERIZATION; DNA-BINDING PROTEINS; HELIX-LOOP-HELIX MOTIFS; LEUCINE ZIPPERS; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0030782191     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.23.12274     Document Type: Article

References (31)

1. Murre, C., McCaw, P. & Baltimore, D. (1989) Cell 56, 777-783.
2. Henriksson, M. & Luscher, B. (1996) Adv. Cancer Res. 68, 109-182.
3. Hodgkinson, C. A., Moore, K. J., Nakayama, A., Steingrimsson, E., Copeland, N. G., Jenkins, N. A. & Arnheiter, H. (1993) Cell 74, 395-404.
4. Ferre-D'Amare, A., Prendergast, G., Ziff, E. & Burley, S. (1993) Nature (London) 363, 38-44.
5. Ellenberger, T., Fass, D., Arnaud, M. & Harrison, S. (1994) Genes Dev. 8, 970-980.
6. Ferre-D'Amare, A., Pognonnec, P., Roeder, R. & Burley, S. (1994) EMBO J. 13, 180-189.
7. Clark, A. & Docherty, K. (1993) Biochem. J. 296, 521-541.
8. MacGregor, D., Li, L. & Ziff, E. (1996) J. Cell. Physiol. 167, 95-105.
9. Kim, J. & Spiegelman, B. (1996) Genes Dev. 10, 1096-1107.
10. Studier, F. W. & Moffatt, B. A. (1986) J. Mol. Biol. 189, 113-130.
11. Stanton, L., Fahrlander, P., Tesser, P. & Marcu, K. (1984) Nature (London) 310, 423-425.
12. Blackwood, E. & Eisenman, R. (1991) Science 251, 1221-1227.
13. Krylov, D., Olive, M. & Vinson, C. (1995) EMBO J. 14, 5329-5337.
14. Krylov, D., Mikhailenko, I. & Vinson, C. (1994) EMBO J. 13, 1849-1861.
15. Olive, M., Krylov, D., Echlin, D. R., Gardner, K., Taparowsky, E. & Vinson, C. (1997) J. Biol. Chem. 272, 18586-18594.
16. Bennet, D., Cooper, P., Dexter, T., Devlin, L., Heasman, J. & Nester, B. (1989) Development 105, 379-385.
17. Hemesath, T. J., Steingrimsson, E., McGill, G., Hansen, M. J., Vaught, J., Hodgkinson, C. A., Arnheiter, H., Copeland, N. G., Jenkins, N. A. & Fisher, D. E. (1994) Genes Dev. 8, 2770-2780.
18. Taparowsky, E. J., Heaney, M. L. & Parsons, J. T. (1987) Cancer Res. 47, 4125-4129.
19. Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M. & Wigler, M. (1982) Nature (London) 300, 762-765.
20. Littlewood, T. & Evan, G. (1994) Protein Profile 1, 639-709.
21. Woody, R. & Tinoco, I. (1967) J. Chem. Phys. 46, 4927-4945.
22. Takebayashi, K., Chida, K., Tsukamoto, I., Morii, E., Munakata, H., Arnheiter, H., Kuroki, T., Kitamura, Y. & Nomura, S. (1996) Mol. Cell. Biol. 16, 1203-1211.
23. Davenport, E. & Taparowsky, E. (1992) Exp. Cell Res. 202, 532-540.
24. Herskowitz, I. (1987) Nature (London) 329, 219-222.
25. Roman, C., Cohn, L. & Calame, K. (1991) Science 254, 94-97.
26. Benezra, R., Davis, R., Lockshon, D., Turner, D. & Weintraub, H. (1990) Cell 61, 49-59.
27. Fairman, R., Beran-Steed, R., Anthony-Cahill, S., Lear, J., Stafford, W., DeGrado, W., Benfield, P. & Brenner, S. (1993) Proc. Natl. Acad. Sci. USA 90, 10429-10433.
28. Billaud, M., Isselbacher, K. & Bernards, R. (1993) Proc. Natl. Acad. Sci. USA 90, 2739-2743.
29. Reddy, C., Dasgupta, P., Saikumar, P., Dudek, H., Rauscher, F. & Reddy, E. (1992) Oncogene 7, 2085-2092.
30. Arsura, M., Deshpande, A., Hann, S. & Sonenshein, G. (1995) Mol. Cell. Biol. 15, 6702-6709.
31. Mueller, P. & Wold, B. (1989) Science 246, 780-786.