Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: Implications for the pathogenesis of human nonalcoholic steatohepatitis

American Journal of Pathology

Volumn 170, Issue 3, 2007, Pages 967-980

  Otogawa, Kohji ^a   Kinoshita, Kohji ^a   Fujii, Hideki ^a   Sakabe, Masahide ^a   Shiga, Ryoko ^a   Nakatani, Kazuki ^a   Ikeda, Kazuo ^a   Nakajima, Yuji ^a   Ikura, Yoshihiro ^a   Ueda, Makiko ^a   Arakawa, Tetsuo ^a   Hato, Fumihiko ^b   Kawada, Norifumi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Osaka Seikei University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; EPIDERMAL GROWTH FACTOR; HEME OXYGENASE 1; PHOSPHATIDYLSERINE; TRANSFORMING GROWTH FACTOR BETA1; CYTOKINE; IRON; MESSENGER RNA; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ERYTHROPHAGOCYTOSIS; HEPATITIS; INFLAMMATION; INSULIN RESISTANCE; KUPFFER CELL; LIPID DIET; LIVER FIBROSIS; MACROPHAGE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; STEATOHEPATITIS; ADULT; AGED; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL LINE; DISEASE MODEL; ERYTHROCYTE; FEMALE; FIBROSIS; FLOW CYTOMETRY; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER; METABOLISM; MIDDLE AGED; MOUSE; NICK END LABELING; PATHOLOGY; PHAGOCYTOSIS; PHYSIOLOGY; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; CELL LINE; CYTOKINES; DISEASE MODELS, ANIMAL; DNA PRIMERS; ERYTHROCYTES; FEMALE; FIBROSIS; FLOW CYTOMETRY; HEPATITIS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; IRON; KUPFFER CELLS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; OXIDATIVE STRESS; PHAGOCYTOSIS; PHOSPHATIDYLSERINES; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 34247844680     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060441     Document Type: Article

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