-
2
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
DOI 10.1038/ni1261, PII N1261
-
Park, H., Z. Li, X. O. Yang, S. H. Chang, R. Nurieva, Y. H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6: 1133-1141. (Pubitemid 41541791)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.-H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
3
-
-
41549135632
-
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
-
DOI 10.1016/j.immuni.2008.03.004, PII S1074761308001192
-
Ouyang, W., J. K. Kolls, and Y. Zheng. 2008. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28: 454-467. (Pubitemid 351471762)
-
(2008)
Immunity
, vol.28
, Issue.4
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
4
-
-
40049098958
-
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
DOI 10.1038/nm1710, PII NM1710
-
Aujla, S. J., Y. R. Chan, M. Zheng, M. Fei, D. J. Askew, D. A. Pociask, T. A. Reinhart, F. McAllister, J. Edeal, K. Gaus, et al. 2008. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14: 275-281. (Pubitemid 351347908)
-
(2008)
Nature Medicine
, vol.14
, Issue.3
, pp. 275-281
-
-
Aujla, S.J.1
Chan, Y.R.2
Zheng, M.3
Fei, M.4
Askew, D.J.5
Pociask, D.A.6
Reinhart, T.A.7
McAllister, F.8
Edeal, J.9
Gaus, K.10
Husain, S.11
Kreindler, J.L.12
Dubin, P.J.13
Pilewski, J.M.14
Myerburg, M.M.15
Mason, C.A.16
Iwakura, Y.17
Kolls, J.K.18
-
5
-
-
33846456273
-
IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection
-
DOI 10.1016/j.micinf.2006.10.012, PII S1286457906003753
-
Wu, Q., R. J. Martin, J. G. Rino, R. Breed, R. M. Torres, and H. W. Chu. 2007. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes. Infect. 9: 78-86. (Pubitemid 46149421)
-
(2007)
Microbes and Infection
, vol.9
, Issue.1
, pp. 78-86
-
-
Wu, Q.1
Martin, R.J.2
Rino, J.G.3
Breed, R.4
Torres, R.M.5
Chu, H.W.6
-
6
-
-
33646560950
-
Transforming growth factor-β induces development of the TH17 lineage
-
Mangan, P. R., L. E. Harrington, D. B. O'Quinn, W. S. Helms, D. C. Bullard, C. O. Elson, R. D. Hatton, S. M. Wahl, T. R. Schoeb, and C. T. Weaver. 2006. Transforming growth factor-β induces development of the TH17 lineage. Nature 441: 231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
7
-
-
34547188748
-
H-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
DOI 10.1038/ni1488, PII NI1488
-
Zhou, L., I. I. Ivanov, R. Spolski, R. Min, K. Shenderov, T. Egawa, D. E. Levy, W. J. Leonard, and D. R. Littman. 2007. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8: 967-974. (Pubitemid 47300011)
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
8
-
-
34548125305
-
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez, E. V., G. Napolitani, A. Lanzavecchia, and F. Sallusto. 2007. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8: 942-949.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
9
-
-
33846458998
-
IL-25 regulates Th17 function in autoimmune inflammation
-
DOI 10.1084/jem.20061738
-
Kleinschek, M. A., A. M. Owyang, B. Joyce-Shaikh, C. L. Langrish, Y. Chen, D. M. Gorman, W. M. Blumenschein, T. McClanahan, F. Brombacher, S. D. Hurst, et al. 2007. IL-25 regulates Th17 function in autoimmune inflammation. J. Exp. Med. 204: 161-170. (Pubitemid 46148766)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.1
, pp. 161-170
-
-
Kleinschek, M.A.1
Owyang, A.M.2
Joyce-Shaikh, B.3
Langrish, C.L.4
Chen, Y.5
Gorman, D.M.6
Blumenschein, W.M.7
McClanahan, T.8
Brombacher, F.9
Hurst, S.D.10
Kastelein, R.A.11
Cua, D.J.12
-
10
-
-
58149143039
-
Tuning sensitivity to IL-4 and IL-13: Differential expression of IL-4Rα, IL-13Ralpha1, and γc regulates relative cytokine sensitivity
-
Junttila, I. S., K. Mizukami, H. Dickensheets, M. Meier-Schellersheim, H. Yamane, R. P. Donnelly, and W. E. Paul. 2008. Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Ralpha1, and γc regulates relative cytokine sensitivity. J. Exp. Med. 205: 2595-2608.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2595-2608
-
-
Junttila, I.S.1
Mizukami, K.2
Dickensheets, H.3
Meier-Schellersheim, M.4
Yamane, H.5
Donnelly, R.P.6
Paul, W.E.7
-
11
-
-
33847782410
-
2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells
-
DOI 10.1189/jlb.0606375
-
Zhou, W., T. S. Blackwell, K. Goleniewska, J. F. O'Neal, G. A. FitzGerald, M. Lucitt, R. M. Breyer, and R. S. Peebles, Jr. 2007. Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells. J. Leukocyte Biol. 81: 809-817. (Pubitemid 46393559)
-
(2007)
Journal of Leukocyte Biology
, vol.81
, Issue.3
, pp. 809-817
-
-
Zhou, W.1
Blackwell, T.S.2
Goleniewska, K.3
O'Neal, J.F.4
Fitzgerald, G.A.5
Lucitt, M.6
Breyer, R.M.7
Peebles Jr., R.S.8
-
12
-
-
0037393323
-
IL-13 receptors and signaling pathways: An evolving web
-
Hershey, G. K. 2003. IL-13 receptors and signaling pathways: an evolving web. J. Allergy Clin. Immunol. 111: 677-690.
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 677-690
-
-
Hershey, G.K.1
-
13
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama, Y., S. Nakae, T. Matsuki, A. Nambu, H. Ishigame, S. Kakuta, K. Sudo, and Y. Iwakura. 2006. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J. Immunol. 177: 566-573. (Pubitemid 43939170)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
Nambu, A.4
Ishigame, H.5
Kakuta, S.6
Sudo, K.7
Iwakura, Y.8
-
14
-
-
0030584699
-
IL-13 induces phosphorylation and activation of JAK2 janus kinase in human colon carcinoma cell lines: Similarities between IL-4 and IL-13 signaling
-
Murata, T., P. D. Noguchi, and R. K. Puri. 1996. IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. J. Immunol. 156: 2972-2978. (Pubitemid 126660646)
-
(1996)
Journal of Immunology
, vol.156
, Issue.8
, pp. 2972-2978
-
-
Murata, T.1
Noguchi, P.D.2
Puri, R.K.3
-
15
-
-
0037184088
-
Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling
-
Andrews, R. P., M. B. Ericksen, C. M. Cunningham, M. O. Daines, and G. K. Hershey. 2002. Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling. J. Biol. Chem. 277: 36563-36569.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36563-36569
-
-
Andrews, R.P.1
Ericksen, M.B.2
Cunningham, C.M.3
Daines, M.O.4
Hershey, G.K.5
-
16
-
-
33748588423
-
+ T helper cells
-
+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
17
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
18
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
DOI 10.1038/nature05969, PII NATURE05969
-
Nurieva, R., X. O. Yang, G. Martinez, Y. Zhang, A. D. Panopoulos, L. Ma, K. Schluns, Q. Tian, S. S. Watowich, A. M. Jetten, and C. Dong. 2007. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448: 480-483. (Pubitemid 47123514)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
Schluns, K.7
Tian, Q.8
Watowich, S.S.9
Jetten, A.M.10
Dong, C.11
-
19
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
DOI 10.1126/science.282.5397.2258
-
Wills-Karp, M., J. Luyimbazi, X. Xu, B. Schofield, T. Y. Neben, C. L. Karp, and D. D. Donaldson. 1998. Interleukin-13: central mediator of allergic asthma. Science 282: 2258-2261. (Pubitemid 29004074)
-
(1998)
Science
, vol.282
, Issue.5397
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
20
-
-
34247522910
-
IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys
-
DOI 10.1016/j.jaci.2007.02.009, PII S0091674907003752
-
Bree, A., F. J. Schlerman, M. Wadanoli, L. Tchistiakova, K. Marquette, X. Y. Tan, B. A. Jacobson, A. Widom, T. A. Cook, N. Wood, et al. 2007. IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys. J. Allergy Clin. Immunol. 119: 1251-1257. (Pubitemid 46654187)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.119
, Issue.5
, pp. 1251-1257
-
-
Bree, A.1
Schlerman, F.J.2
Wadanoli, M.3
Tchistiakova, L.4
Marquette, K.5
Tan, X.-Y.6
Jacobson, B.A.7
Widom, A.8
Cook, T.A.9
Wood, N.10
Vunnum, S.11
Krykbaev, R.12
Xu, X.13
Donaldson, D.D.14
Goldman, S.J.15
Sypek, J.16
Kasaian, M.T.17
-
21
-
-
8444245228
-
Effects of anticytokine therapy in a mouse model of chronic asthma
-
Kumar, R. K., C. Herbert, D. C. Webb, L. Li, and P. S. Foster. 2004. Effects of anticytokine therapy in a mouse model of chronic asthma. Am. J. Respir. Crit Care Med. 170: 1043-1048.
-
(2004)
Am. J. Respir. Crit Care Med.
, vol.170
, pp. 1043-1048
-
-
Kumar, R.K.1
Herbert, C.2
Webb, D.C.3
Li, L.4
Foster, P.S.5
-
22
-
-
9644276704
-
Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling
-
Yang, G., A. Volk, T. Petley, E. Emmell, J. Giles-Komar, X. Shang, J. Li, A. M. Das, D. Shealy, D. E. Griswold, and L. Li. 2004. Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling. Cytokine 28: 224-232.
-
(2004)
Cytokine
, vol.28
, pp. 224-232
-
-
Yang, G.1
Volk, A.2
Petley, T.3
Emmell, E.4
Giles-Komar, J.5
Shang, X.6
Li, J.7
Das, A.M.8
Shealy, D.9
Griswold, D.E.10
Li, L.11
|