Calcineurin-NFAT signaling is involved in phenylephrine-induced vascular smooth muscle cell proliferation

Acta Pharmacologica Sinica

Volumn 30, Issue 5, 2009, Pages 537-544

  Pang, Xiao ^a,b   Sun, Ning Ling ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b SHIHEZI UNIVERSITY   (China)

Author keywords

Calcineurin; Nuclear factor of activated T cells; Phenylephrine; Proliferation; Vascular smooth muscle cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCINEURIN; CHELERYTHRINE; COMPLEMENTARY DNA; CYCLOSPORIN A; LUCIFERASE; PHENYLEPHRINE; PRAZOSIN; TIMOLOL; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DRUG ANTAGONISM; DRUG INHIBITION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; MALE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; REPORTER GENE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCINEURIN; CELL PROLIFERATION; CELLS, CULTURED; MALE; MUSCLE, SMOOTH, VASCULAR; NFATC TRANSCRIPTION FACTORS; PHENYLEPHRINE; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 66749185413     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.28     Document Type: Article

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