메뉴 건너뛰기




Volumn 9, Issue 3, 2009, Pages 243-257

DNA methylation changes in prostate cancer: Current developments and future clinical implementation

Author keywords

DNA methylation; Prostate cancer; Screening serum; Therapy monitoring; Urine

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

EID: 66749182280     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.09.10     Document Type: Review
Times cited : (54)

References (136)
  • 1
  • 3
    • 0037014773 scopus 로고    scopus 로고
    • Understanding and appreciating overdiagnosis in the PSA era
    • Yao SL, Lu-Yao G. Understanding and appreciating overdiagnosis in the PSA era. J. Natl Cancer Inst. 94(13), 958-960 (2002).
    • (2002) J. Natl Cancer Inst , vol.94 , Issue.13 , pp. 958-960
    • Yao, S.L.1    Lu-Yao, G.2
  • 4
    • 0035135616 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of prostatic adenocarcinomas from screening studies: Early cancers may contain aggressive genetic features
    • Alers JC, Krijtenburg PJ, Vis AN et al. Molecular cytogenetic analysis of prostatic adenocarcinomas from screening studies: early cancers may contain aggressive genetic features. Am. J. Pathol. 158(2), 399-406 (2001).
    • (2001) Am. J. Pathol , vol.158 , Issue.2 , pp. 399-406
    • Alers, J.C.1    Krijtenburg, P.J.2    Vis, A.N.3
  • 5
    • 0037304517 scopus 로고    scopus 로고
    • Biochemical (prostate specific antigen) recurrence probability following radical prostatectomy for clinically localized prostate cancer
    • Han M, Partin AW, Zahurak M et al. Biochemical (prostate specific antigen) recurrence probability following radical prostatectomy for clinically localized prostate cancer. J. Urol. 169(2), 517-523 (2003).
    • (2003) J. Urol , vol.169 , Issue.2 , pp. 517-523
    • Han, M.1    Partin, A.W.2    Zahurak, M.3
  • 6
    • 66749138150 scopus 로고    scopus 로고
    • Screening decreases prostate cancer death: First analysis of the 1988 Quebec Prospective Randomized Controlled Trial
    • Barratt AL, Coates AS. Screening decreases prostate cancer death: first analysis of the 1988 Quebec Prospective Randomized Controlled Trial. Med. J. Aust. 181 (4), 213-214 (2004).
    • (2004) Med. J. Aust , vol.181 , Issue.4 , pp. 213-214
    • Barratt, A.L.1    Coates, A.S.2
  • 7
    • 0032894448 scopus 로고    scopus 로고
    • Screening decreases prostate cancer death: First analysis of the 1988 Quebec Prospective Randomized Controlled Trial
    • Labrie F, Candas B, Dupont A et al. Screening decreases prostate cancer death: first analysis of the 1988 Quebec Prospective Randomized Controlled Trial. Prostate 38(2), 83-91 (1999).
    • (1999) Prostate , vol.38 , Issue.2 , pp. 83-91
    • Labrie, F.1    Candas, B.2    Dupont, A.3
  • 9
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird A. The essentials of DNA methylation. Cell 70(1), 5-8 (1992).
    • (1992) Cell , vol.70 , Issue.1 , pp. 5-8
    • Bird, A.1
  • 10
    • 0029011539 scopus 로고
    • 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L et al. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med. 1(7), 686-692 (1995).
    • (1995) Nat. Med , vol.1 , Issue.7 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3
  • 11
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman JG, Umar A, Polyak K et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl Acad. Sci. USA 95(12), 6870-6875 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , Issue.12 , pp. 6870-6875
    • Herman, J.G.1    Umar, A.2    Polyak, K.3
  • 12
    • 27244450828 scopus 로고    scopus 로고
    • Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects
    • Hoque MO, Topaloglu O, Begum S et al. Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects. J. Clin. Oncol. 23(27), 6569-6575 (2005).
    • (2005) J. Clin. Oncol , vol.23 , Issue.27 , pp. 6569-6575
    • Hoque, M.O.1    Topaloglu, O.2    Begum, S.3
  • 13
    • 58749097779 scopus 로고    scopus 로고
    • Concepts of epigenetics in prostate cancer development
    • Cooper CS, Foster CS. Concepts of epigenetics in prostate cancer development. Br. J. Cancer 100(2), 240-245 (2009).
    • (2009) Br. J. Cancer , vol.100 , Issue.2 , pp. 240-245
    • Cooper, C.S.1    Foster, C.S.2
  • 14
    • 34347218944 scopus 로고    scopus 로고
    • Abnormal DNA methylation, epigenetics, and prostate cancer
    • Nelson WG, Yegnasubramanian S, Agoston AT et al. Abnormal DNA methylation, epigenetics, and prostate cancer. Front. Biosci. 12, 4254-4266 (2007).
    • (2007) Front. Biosci , vol.12 , pp. 4254-4266
    • Nelson, W.G.1    Yegnasubramanian, S.2    Agoston, A.T.3
  • 15
    • 33846854438 scopus 로고    scopus 로고
    • The expanding role of epigenetics in the development, diagnosis and treatment of prostate cancer and benign prostatic hyperplasia
    • Dobosy JR, Roberts JL, Fu VX, Jarrard DF. The expanding role of epigenetics in the development, diagnosis and treatment of prostate cancer and benign prostatic hyperplasia. J. Urol. 177(3), 822-831 (2007).
    • (2007) J. Urol , vol.177 , Issue.3 , pp. 822-831
    • Dobosy, J.R.1    Roberts, J.L.2    Fu, V.X.3    Jarrard, D.F.4
  • 16
    • 34347203711 scopus 로고    scopus 로고
    • Epigenetics of prostate cancer
    • Li LC. Epigenetics of prostate cancer. Front. Biosci. 12, 3377-3397 (2007).
    • (2007) Front. Biosci , vol.12 , pp. 3377-3397
    • Li, L.C.1
  • 17
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 8(4), 286-298 (2007).
    • (2007) Nat. Rev. Genet , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 18
    • 42349107016 scopus 로고    scopus 로고
    • Genome-wide promoter analysis unc overs portions of the cancer methylome
    • Hoque MO, Kim MS, Ostrow KL et al. Genome-wide promoter analysis unc overs portions of the cancer methylome. Cancer Res. 68(8), 2661-2670 (2008).
    • (2008) Cancer Res , vol.68 , Issue.8 , pp. 2661-2670
    • Hoque, M.O.1    Kim, M.S.2    Ostrow, K.L.3
  • 19
    • 0034751510 scopus 로고    scopus 로고
    • Remarkable application of serum EBV EBER-1 in monitoring response of nasopharyngeal cancer patients to salvage chemotherapy
    • Ngan RK, Lau WH, Yip TT et al. Remarkable application of serum EBV EBER-1 in monitoring response of nasopharyngeal cancer patients to salvage chemotherapy. Ann. NY Acad. Sci. 945, 73-79 (2001).
    • (2001) Ann. NY Acad. Sci , vol.945 , pp. 73-79
    • Ngan, R.K.1    Lau, W.H.2    Yip, T.T.3
  • 20
    • 0034802738 scopus 로고    scopus 로고
    • Prognostic implication of pretreatment plasma/serum concentration of Epstein-Barr virus DNA in nasopharyngeal carcinoma
    • Lo YM. Prognostic implication of pretreatment plasma/serum concentration of Epstein-Barr virus DNA in nasopharyngeal carcinoma. Biomed. Pharmacother. 55(7), 362-365 (2001).
    • (2001) Biomed. Pharmacother , vol.55 , Issue.7 , pp. 362-365
    • Lo, Y.M.1
  • 21
    • 0025782858 scopus 로고
    • Identification of p53 gene mutations in bladder cancers and urine samples
    • Sidransky D, Von Eschenbach A, Tsai YC et al. Identification of p53 gene mutations in bladder cancers and urine samples. Science 252(5006), 706-709 (1991).
    • (1991) Science , vol.252 , Issue.5006 , pp. 706-709
    • Sidransky, D.1    Von Eschenbach, A.2    Tsai, Y.C.3
  • 22
    • 34250802601 scopus 로고    scopus 로고
    • Gene methylation and early detection of genitourinary cancer: The road ahead
    • Cairns P. Gene methylation and early detection of genitourinary cancer: the road ahead. Nat. Rev. Cancer 7(7), 531-543 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , Issue.7 , pp. 531-543
    • Cairns, P.1
  • 23
    • 3442894720 scopus 로고    scopus 로고
    • Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
    • Hoque MO, Begum S, Topaloglu O et al. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res. 64(15), 5511-5517 (2004).
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5511-5517
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3
  • 24
    • 1842426642 scopus 로고    scopus 로고
    • Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer
    • Topaloglu O, Hoque MO, Tokumaru Y et al. Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer. Clin. Cancer Res. 10(7), 2284-2288 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.7 , pp. 2284-2288
    • Topaloglu, O.1    Hoque, M.O.2    Tokumaru, Y.3
  • 25
    • 33746716987 scopus 로고    scopus 로고
    • Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection
    • Hoque MO, Begum S, Topaloglu O et al. Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection. J. Natl Cancer Inst. 98(14), 996-1004 (2006).
    • (2006) J. Natl Cancer Inst , vol.98 , Issue.14 , pp. 996-1004
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3
  • 26
    • 33749024160 scopus 로고    scopus 로고
    • Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer
    • Hoque MO, Feng Q, Toure P et al. Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer. J. Clin. Oncol. 24(26), 4262-4269 (2006).
    • (2006) J. Clin. Oncol , vol.24 , Issue.26 , pp. 4262-4269
    • Hoque, M.O.1    Feng, Q.2    Toure, P.3
  • 27
    • 33750435596 scopus 로고    scopus 로고
    • Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer
    • Henrique R, Costa VL, Cerveira N et al. Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer. J. Mol. Med. 84(11), 911-918 (2006).
    • (2006) J. Mol. Med , vol.84 , Issue.11 , pp. 911-918
    • Henrique, R.1    Costa, V.L.2    Cerveira, N.3
  • 28
    • 16844374138 scopus 로고    scopus 로고
    • Frequent 14-13-3s promoter methylation in benign and malignant prostate lesions
    • Henrique R, Jeronimo C, Hoque MO et al. Frequent 14-13-3s promoter methylation in benign and malignant prostate lesions. DNA Cell Biol. 24(4), 264-269 (2005).
    • (2005) DNA Cell Biol , vol.24 , Issue.4 , pp. 264-269
    • Henrique, R.1    Jeronimo, C.2    Hoque, M.O.3
  • 29
    • 20844459807 scopus 로고    scopus 로고
    • MT1G hypermethylation is associated with higher tumor stage in prostate cancer
    • Henrique R, Jeronimo C, Hoque MO et al. MT1G hypermethylation is associated with higher tumor stage in prostate cancer. Cancer Epidemiol. Biomarkers Prev. 14(5), 1274-1278 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , Issue.5 , pp. 1274-1278
    • Henrique, R.1    Jeronimo, C.2    Hoque, M.O.3
  • 30
    • 32944480348 scopus 로고    scopus 로고
    • Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: Clues for clonal progression in prostate carcinogenesis
    • Henrique R, Jeronimo C, Teixeira MR et al. Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis. Mol. Cancer Res. 4(1), 1-8 (2006).
    • (2006) Mol. Cancer Res , vol.4 , Issue.1 , pp. 1-8
    • Henrique, R.1    Jeronimo, C.2    Teixeira, M.R.3
  • 31
    • 35948929442 scopus 로고    scopus 로고
    • High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients
    • Henrique R, Ribeiro FR, Fonseca D et al. High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients. Clin. Cancer Res. 13(20), 6122-6129 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.20 , pp. 6122-6129
    • Henrique, R.1    Ribeiro, F.R.2    Fonseca, D.3
  • 32
    • 19944429845 scopus 로고    scopus 로고
    • A qu antitative promoter methylation profile of prostate cancer
    • Jeronimo C, Henrique R, Hoque MO et al. A qu antitative promoter methylation profile of prostate cancer. Clin. CancerRes. 10(24), 8472-8478 (2004).
    • (2004) Clin. CancerRes , vol.10 , Issue.24 , pp. 8472-8478
    • Jeronimo, C.1    Henrique, R.2    Hoque, M.O.3
  • 33
    • 0036899057 scopus 로고    scopus 로고
    • Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer
    • Jeronimo C, Usadel H, Henrique R et al. Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer. Urology 60(6), 1131-1135 (2002).
    • (2002) Urology , vol.60 , Issue.6 , pp. 1131-1135
    • Jeronimo, C.1    Usadel, H.2    Henrique, R.3
  • 34
    • 0041924823 scopus 로고    scopus 로고
    • Hypermethylation of the human glutathione S-transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: A detailed study using laser-capture microdissection
    • Nakayama M, Bennett CJ, Hicks JL et al. Hypermethylation of the human glutathione S-transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: a detailed study using laser-capture microdissection. Am. J. Pathol. 163(3), 923-933 (2003).
    • (2003) Am. J. Pathol , vol.163 , Issue.3 , pp. 923-933
    • Nakayama, M.1    Bennett, C.J.2    Hicks, J.L.3
  • 35
    • 33644834687 scopus 로고    scopus 로고
    • E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial- to-mesenchymal transition in breast cancer cell lines
    • Lombaerts M, van Wezel T, Philippo K et al. E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial- to-mesenchymal transition in breast cancer cell lines. Br. J. Cancer 94(5), 661-671 (2006).
    • (2006) Br. J. Cancer , vol.94 , Issue.5 , pp. 661-671
    • Lombaerts, M.1    van Wezel, T.2    Philippo, K.3
  • 36
    • 3242756641 scopus 로고    scopus 로고
    • Age-dependent methylation of ESR1 gene in prostate cancer
    • Li LC, Shiina H, Deguchi M et al. Age-dependent methylation of ESR1 gene in prostate cancer. Biochem. Biophys. Res. Commun. 321(2), 455-461 (2004).
    • (2004) Biochem. Biophys. Res. Commun , vol.321 , Issue.2 , pp. 455-461
    • Li, L.C.1    Shiina, H.2    Deguchi, M.3
  • 37
    • 34948842950 scopus 로고    scopus 로고
    • Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer
    • Wang Q, Williamson M, Bott S et al. Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer. Oncogene 26(45), 6560-6565 (2007).
    • (2007) Oncogene , vol.26 , Issue.45 , pp. 6560-6565
    • Wang, Q.1    Williamson, M.2    Bott, S.3
  • 38
    • 66349100130 scopus 로고    scopus 로고
    • DNA methylation and aberrant expression of sprouty1 in human prostate cancer
    • Kwabi-Addo B, Ren C, Ittmann M. DNA methylation and aberrant expression of sprouty1 in human prostate cancer.Epigenetics 4(1) (2009).
    • (2009) Epigenetics , vol.4 , Issue.1
    • Kwabi-Addo, B.1    Ren, C.2    Ittmann, M.3
  • 39
    • 33645917663 scopus 로고    scopus 로고
    • Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer
    • Wang J, Thompson B, Ren C, Ittmann M, Kwabi-Addo B. Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer. Prostate 66(6), 613-624 (2006).
    • (2006) Prostate , vol.66 , Issue.6 , pp. 613-624
    • Wang, J.1    Thompson, B.2    Ren, C.3    Ittmann, M.4    Kwabi-Addo, B.5
  • 40
    • 25144433754 scopus 로고    scopus 로고
    • Multigene methylation analysis for detection and staging of prostate cancer
    • Enokida H, Shiina H, Urakami S et al. Multigene methylation analysis for detection and staging of prostate cancer. Clin. Cancer Res. 11(18), 6582-6588 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.18 , pp. 6582-6588
    • Enokida, H.1    Shiina, H.2    Urakami, S.3
  • 41
    • 33748107438 scopus 로고    scopus 로고
    • Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer
    • Suzuki M, Shigematsu H, Shivapurkar N et al. Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer. Cancer Lett. 242(2), 222-230 (2006).
    • (2006) Cancer Lett , vol.242 , Issue.2 , pp. 222-230
    • Suzuki, M.1    Shigematsu, H.2    Shivapurkar, N.3
  • 42
    • 41749119194 scopus 로고    scopus 로고
    • Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma
    • Bachmann N, Haeusler J, Luedeke M et al. Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma. Cancer Genet. Cytogenet. 182(2), 103-110 (2008).
    • (2008) Cancer Genet. Cytogenet , vol.182 , Issue.2 , pp. 103-110
    • Bachmann, N.1    Haeusler, J.2    Luedeke, M.3
  • 43
    • 0035130638 scopus 로고    scopus 로고
    • Hypermethylation of the caveolin-1 gene promoter in prostate cancer
    • Cui J, Rohr LR, Swanson G et al. Hypermethylation of the caveolin-1 gene promoter in prostate cancer. Prostate 46(3), 249-256 (2001).
    • (2001) Prostate , vol.46 , Issue.3 , pp. 249-256
    • Cui, J.1    Rohr, L.R.2    Swanson, G.3
  • 44
    • 0142188174 scopus 로고    scopus 로고
    • Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation
    • Padar A, Sathyanarayana UG, Suzuki M et al. Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation. Clin. Cancer Res. 9(13), 4730-4734 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.13 , pp. 4730-4734
    • Padar, A.1    Sathyanarayana, U.G.2    Suzuki, M.3
  • 45
    • 28544442448 scopus 로고    scopus 로고
    • Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy
    • Rosenbaum E, Hoque MO, Cohen Y et al. Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy. Clin. Cancer Res. 11(23), 8321-8325 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.23 , pp. 8321-8325
    • Rosenbaum, E.1    Hoque, M.O.2    Cohen, Y.3
  • 46
    • 33144465069 scopus 로고    scopus 로고
    • Gene promoter methylation in prostate tumor-associated stromal cells
    • Hanson JA, Gillespie JW, Grover A et al. Gene promoter methylation in prostate tumor-associated stromal cells. J. Natl Cancer Inst. 98(4), 255-261 (2006).
    • (2006) J. Natl Cancer Inst , vol.98 , Issue.4 , pp. 255-261
    • Hanson, J.A.1    Gillespie, J.W.2    Grover, A.3
  • 47
    • 0037738934 scopus 로고    scopus 로고
    • Hypermethylation of GSTP1, CD44, and E-cadherin genes in prostate cancer among US Blacks and Whites
    • Woodson K, Hayes R, Wideroff L, Villaruz L, Tangrea J. Hypermethylation of GSTP1, CD44, and E-cadherin genes in prostate cancer among US Blacks and Whites. Prostate 55(3), 199-205 (2003).
    • (2003) Prostate , vol.55 , Issue.3 , pp. 199-205
    • Woodson, K.1    Hayes, R.2    Wideroff, L.3    Villaruz, L.4    Tangrea, J.5
  • 48
    • 38449120703 scopus 로고    scopus 로고
    • CD44 and PTGS2 methylation are independent prognostic markers for biochemical recurrence among prostate cancer patients with clinically localized disease
    • Woodson K, O'Reilly KJ, Ward DE et al. CD44 and PTGS2 methylation are independent prognostic markers for biochemical recurrence among prostate cancer patients with clinically localized disease. Epigenetics 1(4), 183-186 (2006).
    • (2006) Epigenetics , vol.1 , Issue.4 , pp. 183-186
    • Woodson, K.1    O'Reilly, K.J.2    Ward, D.E.3
  • 49
    • 60849121725 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer
    • Cheng Y, Kim JW, Liu W et al. Genetic and epigenetic inactivation of TNFRSF10C in human prostate cancer. Prostate 69(3), 327-335 (2009).
    • (2009) Prostate , vol.69 , Issue.3 , pp. 327-335
    • Cheng, Y.1    Kim, J.W.2    Liu, W.3
  • 50
    • 0038505597 scopus 로고    scopus 로고
    • ltered methylation of multiple genes in carcinogenesis of the prostate
    • Yamanaka M, Watanabe M, Yamada Y et al. ltered methylation of multiple genes in carcinogenesis of the prostate. Int. J. Cancer 106(3), 382-387 (2003).
    • (2003) Int. J. Cancer , vol.106 , Issue.3 , pp. 382-387
    • Yamanaka, M.1    Watanabe, M.2    Yamada, Y.3
  • 51
    • 0031026396 scopus 로고    scopus 로고
    • Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer
    • Nelson JB, Lee WH, Nguyen SH et al. Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer. Cancer Res. 57(1), 35-37 (1997).
    • (1997) Cancer Res , vol.57 , Issue.1 , pp. 35-37
    • Nelson, J.B.1    Lee, W.H.2    Nguyen, S.H.3
  • 52
    • 0037245645 scopus 로고    scopus 로고
    • Endothelin B receptor gene hypermethylation in prostate adenocarcinoma
    • Jeronimo C, Henrique R, Campos PF et al. Endothelin B receptor gene hypermethylation in prostate adenocarcinoma. J. Clin. Pathol. 56(1), 52-55 (2003).
    • (2003) J. Clin. Pathol , vol.56 , Issue.1 , pp. 52-55
    • Jeronimo, C.1    Henrique, R.2    Campos, P.F.3
  • 53
    • 12144289173 scopus 로고    scopus 로고
    • Hypermethylation of CpG islands in primary and metastatic human prostate cancer
    • Yegnasubramanian S, Kowalski J, Gonzalgo ML et al. Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Res. 64(6), 1975-1986 (2004).
    • (2004) Cancer Res , vol.64 , Issue.6 , pp. 1975-1986
    • Yegnasubramanian, S.1    Kowalski, J.2    Gonzalgo, M.L.3
  • 54
    • 38549173539 scopus 로고    scopus 로고
    • Rationale and clinical implication of combined chemotherapy with cisplatin and oestrogen in prostate cancer: Primary evidence based on methylation analysis of oestrogen receptor-a
    • Moriyama-Gonda N, Shiina H, Terashima M, Satoh K, Igawa M. Rationale and clinical implication of combined chemotherapy with cisplatin and oestrogen in prostate cancer: primary evidence based on methylation analysis of oestrogen receptor-a. BJU Int. 101(4), 485-491 (2008).
    • (2008) BJU Int , vol.101 , Issue.4 , pp. 485-491
    • Moriyama-Gonda, N.1    Shiina, H.2    Terashima, M.3    Satoh, K.4    Igawa, M.5
  • 55
    • 0037029021 scopus 로고    scopus 로고
    • Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer
    • Sasaki M, Tanaka Y, Perinchery G et al. Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer. J. Natl Cancer Inst. 94(5), 384-390 (2002).
    • (2002) J. Natl Cancer Inst , vol.94 , Issue.5 , pp. 384-390
    • Sasaki, M.1    Tanaka, Y.2    Perinchery, G.3
  • 56
    • 0034126666 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER)-a and ER-p in normal and malignant prostatic epithelial cells: Regulation by methylation and involvement in growth regulation
    • Lau KM, LaSpina M, Long J, Ho SM. Expression of estrogen receptor (ER)-a and ER-p in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Res. 60(12), 3175-3182 (2000).
    • (2000) Cancer Res , vol.60 , Issue.12 , pp. 3175-3182
    • Lau, K.M.1    LaSpina, M.2    Long, J.3    Ho, S.M.4
  • 57
    • 2442676740 scopus 로고    scopus 로고
    • Dynamic regulation of estrogen receptor-p expression by DNA methylation during prostate cancer development and metastasis
    • Zhu X, Leav I, Leung YK et al. Dynamic regulation of estrogen receptor-p expression by DNA methylation during prostate cancer development and metastasis. Am. J. Pathol. 164(6), 2003-2012 (2004).
    • (2004) Am. J. Pathol , vol.164 , Issue.6 , pp. 2003-2012
    • Zhu, X.1    Leav, I.2    Leung, Y.K.3
  • 58
    • 0036184623 scopus 로고    scopus 로고
    • Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features
    • Maruyama R, Toyooka S, Toyooka KO et al. Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features. Clin. Cancer Res. 8(2), 514-519 (2002).
    • (2002) Clin. Cancer Res , vol.8 , Issue.2 , pp. 514-519
    • Maruyama, R.1    Toyooka, S.2    Toyooka, K.O.3
  • 59
    • 0028152397 scopus 로고
    • Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
    • Lee WH, Morton RA, Epstein JI et al. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc. Natl Acad. Sci. USA 91(24), 11733-11737 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , Issue.24 , pp. 11733-11737
    • Lee, W.H.1    Morton, R.A.2    Epstein, J.I.3
  • 60
    • 0035930097 scopus 로고    scopus 로고
    • Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma
    • Jeronimo C, Usadel H, Henrique R et al. Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. J. Natl Cancer Inst. 93(22), 1747-1752 (2001).
    • (2001) J. Natl Cancer Inst , vol.93 , Issue.22 , pp. 1747-1752
    • Jeronimo, C.1    Usadel, H.2    Henrique, R.3
  • 61
    • 58149286579 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of LPL gene in human prostate cancer
    • Kim JW, Cheng Y, Liu W et al. Genetic and epigenetic inactivation of LPL gene in human prostate cancer. Int. J. Cancer 124(3), 734-738 (2009).
    • (2009) Int. J. Cancer , vol.124 , Issue.3 , pp. 734-738
    • Kim, J.W.1    Cheng, Y.2    Liu, W.3
  • 62
    • 0346963111 scopus 로고    scopus 로고
    • Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features
    • Sathyanarayana UG, Padar A, M et al. Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features. Clin. Cancer Res. 9(17), 6395-6400 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.17 , pp. 6395-6400
    • Sathyanarayana, U.G.1    Padar, A.M.2
  • 63
    • 20344374987 scopus 로고    scopus 로고
    • Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci
    • Bastian PJ, Ellinger J, Wellmann A et al. Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci. Clin. Cancer Res. 11(11), 4097-4106 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.11 , pp. 4097-4106
    • Bastian, P.J.1    Ellinger, J.2    Wellmann, A.3
  • 64
    • 3042619078 scopus 로고    scopus 로고
    • Quantitative RAR§2 hypermethylation: A promising prostate cancer marker
    • Jeronimo C, Henrique R, Hoque MO et al. Quantitative RAR§2 hypermethylation: a promising prostate cancer marker. Clin. Cancer Res. 10(12 Pt 1), 4010-4014 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.12 PART 1 , pp. 4010-4014
    • Jeronimo, C.1    Henrique, R.2    Hoque, M.O.3
  • 65
    • 0037015688 scopus 로고    scopus 로고
    • Frequent hypermethylation of the RASSF1A gene in prostate cancer
    • Liu L, Yoon JH, Dammann R, Pfeifer GP. Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene 21(44), 6835-6840 (2002).
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6835-6840
    • Liu, L.1    Yoon, J.H.2    Dammann, R.3    Pfeifer, G.P.4
  • 66
    • 55049137801 scopus 로고    scopus 로고
    • Methylation screening of the TGFBI promoter in human lung and prostate cancer by methylation-specific PCR
    • Shah JN, Shao G, Hei TK, Zhao Y. Methylation screening of the TGFBI promoter in human lung and prostate cancer by methylation-specific PCR. BMC Cancer 8, 284 (2008).
    • (2008) BMC Cancer , vol.8 , pp. 284
    • Shah, J.N.1    Shao, G.2    Hei, T.K.3    Zhao, Y.4
  • 67
    • 58149402919 scopus 로고    scopus 로고
    • Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features
    • Guan M, Xu C, Zhang F, Ye C. Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features. Int. J. Cancer 124(1), 88-94 (2009).
    • (2009) Int. J. Cancer , vol.124 , Issue.1 , pp. 88-94
    • Guan, M.1    Xu, C.2    Zhang, F.3    Ye, C.4
  • 68
    • 53349141350 scopus 로고    scopus 로고
    • Sox7 Is an independent checkpoint for p-catenin function in prostate and colon epithelial cells
    • Guo L, Zhong D, Lau S et al. Sox7 Is an independent checkpoint for p-catenin function in prostate and colon epithelial cells. Mol. Cancer Res. 6(9), 1421-1430 (2008).
    • (2008) Mol. Cancer Res , vol.6 , Issue.9 , pp. 1421-1430
    • Guo, L.1    Zhong, D.2    Lau, S.3
  • 69
    • 42949087886 scopus 로고    scopus 로고
    • Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer
    • Aitchison AA, Veerakumarasivam A, Vias M et al. Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer. Prostate 68(6), 661-674 (2008).
    • (2008) Prostate , vol.68 , Issue.6 , pp. 661-674
    • Aitchison, A.A.1    Veerakumarasivam, A.2    Vias, M.3
  • 70
    • 37449002884 scopus 로고    scopus 로고
    • Higuchi T, Nakamura M, Shimada K et al. HRK inactivation associated with promoter methylation and LOH in prostate cancer. Prostate 68(1), 105-113 (2008).
    • Higuchi T, Nakamura M, Shimada K et al. HRK inactivation associated with promoter methylation and LOH in prostate cancer. Prostate 68(1), 105-113 (2008).
  • 71
    • 34548572037 scopus 로고    scopus 로고
    • Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis
    • Yu YP, Yu G, Tseng G et al. Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis. Cancer Res. 67(17), 8043-8050 (2007).
    • (2007) Cancer Res , vol.67 , Issue.17 , pp. 8043-8050
    • Yu, Y.P.1    Yu, G.2    Tseng, G.3
  • 72
    • 34547728776 scopus 로고    scopus 로고
    • Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors
    • Pulukuri SM, Patibandla S, Patel J, Estes N, Rao JS. Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors. Oncogene 26(36), 5229-5237 (2007).
    • (2007) Oncogene , vol.26 , Issue.36 , pp. 5229-5237
    • Pulukuri, S.M.1    Patibandla, S.2    Patel, J.3    Estes, N.4    Rao, J.S.5
  • 73
    • 33646690509 scopus 로고    scopus 로고
    • Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer
    • Leiblich A, Cross SS, Catto JW et al. Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer. Oncogene 25 (20), 2953-2960 (2006).
    • (2006) Oncogene , vol.25 , Issue.20 , pp. 2953-2960
    • Leiblich, A.1    Cross, S.S.2    Catto, J.W.3
  • 74
    • 33645058409 scopus 로고    scopus 로고
    • Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: Potential clinical applications
    • Guan M, Zhou X, Soulitzis N, Spandidos DA, Popescu NC. Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications. Clin. Cancer Res. 12(5), 1412-1419 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.5 , pp. 1412-1419
    • Guan, M.1    Zhou, X.2    Soulitzis, N.3    Spandidos, D.A.4    Popescu, N.C.5
  • 75
    • 33644768137 scopus 로고    scopus 로고
    • PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer
    • Vanaja DK, Ballman KV, Morlan BW et al. PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. Clin. Cancer Res. 12(4), 1128-1136 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.4 , pp. 1128-1136
    • Vanaja, D.K.1    Ballman, K.V.2    Morlan, B.W.3
  • 76
    • 33144462429 scopus 로고    scopus 로고
    • CSR1 suppresses tumor growth and metastasis of prostate cancer
    • Yu G, Tseng GC, Yu YP et al. CSR1 suppresses tumor growth and metastasis of prostate cancer. Am. J. Pathol. 168(2), 597-607 (2006).
    • (2006) Am. J. Pathol , vol.168 , Issue.2 , pp. 597-607
    • Yu, G.1    Tseng, G.C.2    Yu, Y.P.3
  • 77
    • 24944556612 scopus 로고    scopus 로고
    • The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer
    • Kim H, Lapointe J, Kaygusuz G et al. The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. Cancer Res. 65(18), 8118-8124 (2005).
    • (2005) Cancer Res , vol.65 , Issue.18 , pp. 8118-8124
    • Kim, H.1    Lapointe, J.2    Kaygusuz, G.3
  • 78
    • 27144519672 scopus 로고    scopus 로고
    • Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer
    • Ropke A, Buhtz P, Bohm M et al. Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer. Oncogene 24(44), 6667-6675 (2005).
    • (2005) Oncogene , vol.24 , Issue.44 , pp. 6667-6675
    • Ropke, A.1    Buhtz, P.2    Bohm, M.3
  • 79
    • 1842538757 scopus 로고    scopus 로고
    • Methylation of the retinoid response gene TIG1 in prostate cancer correlates with methylation of the retinoic acid receptor b gene
    • Zhang J, Liu L, Pfeifer GP. Methylation of the retinoid response gene TIG1 in prostate cancer correlates with methylation of the retinoic acid receptor b gene. Oncogene 23(12), 2241-2249 (2004).
    • (2004) Oncogene , vol.23 , Issue.12 , pp. 2241-2249
    • Zhang, J.1    Liu, L.2    Pfeifer, G.P.3
  • 80
    • 0038718516 scopus 로고    scopus 로고
    • Tokumaru Y, Sun DI, Nomoto S, Yamashita K, Sidransky D. Re: is TIG1 a new tumor suppressor in prostate cancer? J. Natl Cancer Inst. 95(12), 919-920 (2003).
    • Tokumaru Y, Sun DI, Nomoto S, Yamashita K, Sidransky D. Re: is TIG1 a new tumor suppressor in prostate cancer? J. Natl Cancer Inst. 95(12), 919-920 (2003).
  • 81
    • 0036900330 scopus 로고    scopus 로고
    • Epigenetics in cancer: Implications for early detection and prevention
    • Verma M, Srivastava S. Epigenetics in cancer: implications for early detection and prevention. Lancet Oncol. 3(12), 755-763 (2002).
    • (2002) Lancet Oncol , vol.3 , Issue.12 , pp. 755-763
    • Verma, M.1    Srivastava, S.2
  • 82
    • 33645521023 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
    • Belinsky SA, Liechty KC, Gentry FD et al. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res. 66(6), 3338-3344 (2006).
    • (2006) Cancer Res , vol.66 , Issue.6 , pp. 3338-3344
    • Belinsky, S.A.1    Liechty, K.C.2    Gentry, F.D.3
  • 83
    • 0034327356 scopus 로고    scopus 로고
    • Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids
    • Goessl C, Krause H, Muller M et al. Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids. Cancer Res. 60(21), 5941-5945
    • Cancer Res , vol.60 , Issue.21 , pp. 5941-5945
    • Goessl, C.1    Krause, H.2    Muller, M.3
  • 84
    • 0037817323 scopus 로고    scopus 로고
    • Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens
    • Gonzalgo ML, Pavlovich CP, Lee SM, Nelson WG. Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens. Clin. Cancer Res. 9(7), 2673-2677 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.7 , pp. 2673-2677
    • Gonzalgo, M.L.1    Pavlovich, C.P.2    Lee, S.M.3    Nelson, W.G.4
  • 85
    • 33644853936 scopus 로고    scopus 로고
    • Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation
    • Yegnasubramanian S, Lin X, Haffner MC, DeMarzo AM, Nelson WG. Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation. Nucleic Acids Res. 34(3), e19 (2006).
    • (2006) Nucleic Acids Res , vol.34 , Issue.3
    • Yegnasubramanian, S.1    Lin, X.2    Haffner, M.C.3    DeMarzo, A.M.4    Nelson, W.G.5
  • 87
    • 0034872916 scopus 로고    scopus 로고
    • DNA-based detection of prostate cancer in urine after prostatic massage
    • Goessl C, Muller M, Heicappell R et al. DNA-based detection of prostate cancer in urine after prostatic massage. Urology 58(3), 335-338 (2001).
    • (2001) Urology , vol.58 , Issue.3 , pp. 335-338
    • Goessl, C.1    Muller, M.2    Heicappell, R.3
  • 88
    • 0034808413 scopus 로고    scopus 로고
    • Molecular detection of prostate cancer in urine by GSTP1 hypermethylation
    • Cairns P, Esteller M, Herman JG et al. Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. Clin. Cancer Res. 7(9), 2727-2730 (2001).
    • (2001) Clin. Cancer Res , vol.7 , Issue.9 , pp. 2727-2730
    • Cairns, P.1    Esteller, M.2    Herman, J.G.3
  • 89
    • 34250172748 scopus 로고    scopus 로고
    • Molecular detection of localize prostate cancer using quantitative methylation- specific PCR on urinary cells obtained following prostate massage
    • Roupret M, Hupertan V, Yates DR et al. Molecular detection of localize prostate cancer using quantitative methylation- specific PCR on urinary cells obtained following prostate massage. Clin. Cancer Res. 13(6), 1720-1725 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.6 , pp. 1720-1725
    • Roupret, M.1    Hupertan, V.2    Yates, D.R.3
  • 90
    • 38849191949 scopus 로고    scopus 로고
    • The usefulness of the detection of GSTP1 methylation in urine as a biomarker in the diagnosis of prostate cancer
    • discussion: 511-502
    • Woodson K, O'Reilly KJ, Hanson JC et al. The usefulness of the detection of GSTP1 methylation in urine as a biomarker in the diagnosis of prostate cancer. J. Urol. 179(2), 508-511; discussion: 511-502 (2008).
    • (2008) J. Urol , vol.179 , Issue.2 , pp. 508-511
    • Woodson, K.1    O'Reilly, K.J.2    Hanson, J.C.3
  • 91
    • 43449117779 scopus 로고    scopus 로고
    • Development of a multiplexed urine assay for prostate cancer diagnosis
    • Vener T, Derecho C, Baden J et al. Development of a multiplexed urine assay for prostate cancer diagnosis. Clin. Chem. 54(5), 874-882 (2008).
    • (2008) Clin. Chem , vol.54 , Issue.5 , pp. 874-882
    • Vener, T.1    Derecho, C.2    Baden, J.3
  • 92
    • 62149107439 scopus 로고    scopus 로고
    • Multimarker circulating DNA assay for assessing blood of prostate cancer patients
    • Sunami E, Shinozaki M, Higano CS et al. Multimarker circulating DNA assay for assessing blood of prostate cancer patients. Clin. Chem. 55(3), 559-67 (2009).
    • (2009) Clin. Chem , vol.55 , Issue.3 , pp. 559-567
    • Sunami, E.1    Shinozaki, M.2    Higano, C.S.3
  • 93
    • 33847386223 scopus 로고    scopus 로고
    • Promoter hypermethylation of GSTP1, AR, and 14-13-3s in serum of prostate cancer patients and its clinical relevance
    • Reibenwein J, Pils D, Horak P et al. Promoter hypermethylation of GSTP1, AR, and 14-13-3s in serum of prostate cancer patients and its clinical relevance. Prostate 67(4), 427-432 (2007).
    • (2007) Prostate , vol.67 , Issue.4 , pp. 427-432
    • Reibenwein, J.1    Pils, D.2    Horak, P.3
  • 94
    • 38849165455 scopus 로고    scopus 로고
    • CpG island hypermethylation profile in the serum of men with clinically localized and hormone refractory metastatic prostate cancer
    • discussion: 534-525
    • Bastian PJ, Palapattu GS, Yegnasubramanian S et al. CpG island hypermethylation profile in the serum of men with clinically localized and hormone refractory metastatic prostate cancer. J. Urol. 179(2), 529-534; discussion: 534-525 (2008).
    • (2008) J. Urol , vol.179 , Issue.2 , pp. 529-534
    • Bastian, P.J.1    Palapattu, G.S.2    Yegnasubramanian, S.3
  • 95
    • 37449024720 scopus 로고    scopus 로고
    • CpG island hypermethylation in cell-free serum DNA identifies patients with localized prostate cancer
    • Ellinger J, Haan K, Heukamp LC et al. CpG island hypermethylation in cell-free serum DNA identifies patients with localized prostate cancer. Prostate 68(1), 42-49 (2008).
    • (2008) Prostate , vol.68 , Issue.1 , pp. 42-49
    • Ellinger, J.1    Haan, K.2    Heukamp, L.C.3
  • 96
    • 34147170557 scopus 로고    scopus 로고
    • Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis
    • Cottrell S, Jung K, Kristiansen G et al. Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis. J. Urol. 177(5), 1753-1758 (2007).
    • (2007) J. Urol , vol.177 , Issue.5 , pp. 1753-1758
    • Cottrell, S.1    Jung, K.2    Kristiansen, G.3
  • 97
    • 33846221516 scopus 로고    scopus 로고
    • Prognostic value of CpG island hypermethylation at PTGS2, RAR-p, EDNRB, and other gene loci in patients undergoing radical prostatectomy
    • discussion: 674
    • Bastian PJ, Ellinger J, Heukamp LC et al. Prognostic value of CpG island hypermethylation at PTGS2, RAR-p, EDNRB, and other gene loci in patients undergoing radical prostatectomy. Eur. Urol. 51(3), 665-674; discussion: 674 (2007).
    • (2007) Eur. Urol , vol.51 , Issue.3 , pp. 665-674
    • Bastian, P.J.1    Ellinger, J.2    Heukamp, L.C.3
  • 98
    • 27644455870 scopus 로고    scopus 로고
    • DNA methylation- associated inactivation of TGFp-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers
    • Suzuki M, Shigematsu H, Shames DS et al. DNA methylation- associated inactivation of TGFp-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers. Br. J. Cancer 93(9), 1029-1037 (2005).
    • (2005) Br. J. Cancer , vol.93 , Issue.9 , pp. 1029-1037
    • Suzuki, M.1    Shigematsu, H.2    Shames, D.S.3
  • 99
    • 20344366824 scopus 로고    scopus 로고
    • Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy
    • Bastian PJ, Palapattu GS, Lin X et al. Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy. Clin. Cancer Res. 11(11), 4037-4043 (2005).
    • (2005) Clin. Cancer Res , vol.11 , Issue.11 , pp. 4037-4043
    • Bastian, P.J.1    Palapattu, G.S.2    Lin, X.3
  • 100
    • 0038732266 scopus 로고    scopus 로고
    • Polymerase chain reaction-based methods of DNA methylation analysis
    • Liu ZJ, Maekawa M. Polymerase chain reaction-based methods of DNA methylation analysis. Anal. Biochem. 317(2), 259-265 (2003).
    • (2003) Anal. Biochem , vol.317 , Issue.2 , pp. 259-265
    • Liu, Z.J.1    Maekawa, M.2
  • 102
    • 0034326238 scopus 로고    scopus 로고
    • Predicting lung cancer by detecting aberrant promoter methylation in sputum
    • Palmisano WA, Divine KK, Saccomanno G et al. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res. 60(21), 5954-5958 (2000).
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 5954-5958
    • Palmisano, W.A.1    Divine, K.K.2    Saccomanno, G.3
  • 103
    • 0037328351 scopus 로고    scopus 로고
    • Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
    • House MG, Guo M, Iacobuzio-Donahue C, Herman JG. Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Carcinogenesis 24(2), 193-198 (2003).
    • (2003) Carcinogenesis , vol.24 , Issue.2 , pp. 193-198
    • House, M.G.1    Guo, M.2    Iacobuzio-Donahue, C.3    Herman, J.G.4
  • 104
    • 0037731713 scopus 로고    scopus 로고
    • Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: The Netherlands cohort study on diet and cancer
    • van Engeland M, Weijenberg MP, Roemen GM et al. Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer Res. 63(12), 3133-3137 (2003).
    • (2003) Cancer Res , vol.63 , Issue.12 , pp. 3133-3137
    • van Engeland, M.1    Weijenberg, M.P.2    Roemen, G.M.3
  • 105
    • 20044372154 scopus 로고    scopus 로고
    • Hegi ME, Diserens AC, Gorlia T et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N. Engl. J. Med. 352(10), 997-1003 (2005).
    • Hegi ME, Diserens AC, Gorlia T et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N. Engl. J. Med. 352(10), 997-1003 (2005).
  • 106
    • 33646367930 scopus 로고    scopus 로고
    • Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings
    • Brena RM, Huang TH, Plass C. Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings. J. Mol. Med. 84(5), 365-377 (2006).
    • (2006) J. Mol. Med , vol.84 , Issue.5 , pp. 365-377
    • Brena, R.M.1    Huang, T.H.2    Plass, C.3
  • 107
    • 19244365868 scopus 로고    scopus 로고
    • A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): Analysis of the retinoblastoma locus
    • Zeschnigk M, Bohringer S, Price EA et al. A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): analysis of the retinoblastoma locus. Nucleic Acids Res. 32(16), e125 (2004).
    • (2004) Nucleic Acids Res , vol.32 , Issue.16
    • Zeschnigk, M.1    Bohringer, S.2    Price, E.A.3
  • 108
    • 0033566692 scopus 로고    scopus 로고
    • Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction
    • Lo YM, Wong IH, Zhang J et al. Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction. Cancer Res. 59(16), 3899-3903 (1999).
    • (1999) Cancer Res , vol.59 , Issue.16 , pp. 3899-3903
    • Lo, Y.M.1    Wong, I.H.2    Zhang, J.3
  • 110
    • 0026099668 scopus 로고
    • Single nucleotide primer extension to detect genetic diseases: Experimental application to hemophilia B (Factor IX) and cystic fibrosis genes
    • Kuppuswamy MN, Hoffmann JW, Kasper CK et al. Single nucleotide primer extension to detect genetic diseases: experimental application to hemophilia B (Factor IX) and cystic fibrosis genes. Proc. Natl Acad. Sci. USA 88(4), 1143-1147 (1991).
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , Issue.4 , pp. 1143-1147
    • Kuppuswamy, M.N.1    Hoffmann, J.W.2    Kasper, C.K.3
  • 111
    • 0026817024 scopus 로고
    • A sensitive, quantitative assay for measurement of allele-specific transcripts differing by a single nucleotide
    • Singer-Sam J, LeBon JM, Dai A, Riggs AD. A sensitive, quantitative assay for measurement of allele-specific transcripts differing by a single nucleotide. PCR Methods Appl. 1(3), 160-163 (1992).
    • (1992) PCR Methods Appl , vol.1 , Issue.3 , pp. 160-163
    • Singer-Sam, J.1    LeBon, J.M.2    Dai, A.3    Riggs, A.D.4
  • 112
    • 0029621799 scopus 로고
    • Allele-specific expression and total expression levels of imprinted genes during early mouse development: Implications for imprinting mechanisms
    • Szabo PE, Mann JR. Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 9(24), 3097-3108 (1995).
    • (1995) Genes Dev , vol.9 , Issue.24 , pp. 3097-3108
    • Szabo, P.E.1    Mann, J.R.2
  • 113
    • 0030014967 scopus 로고    scopus 로고
    • Single nucleotide primer extension: Quantitative range, variability, and multiplex analysis
    • Greenwood AD, Burke DT. Single nucleotide primer extension: quantitative range, variability, and multiplex analysis. Genome Res. 6(4), 336-348 (1996).
    • (1996) Genome Res , vol.6 , Issue.4 , pp. 336-348
    • Greenwood, A.D.1    Burke, D.T.2
  • 114
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo ML, Jones PA. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res. 25(12), 2529-2531 (1997).
    • (1997) Nucleic Acids Res , vol.25 , Issue.12 , pp. 2529-2531
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 115
    • 17444437545 scopus 로고    scopus 로고
    • A real-time PCR assay for DNA- methylation using methylation-specific blockers
    • Cottrell SE, Distler J, Goodman NS et al. A real-time PCR assay for DNA- methylation using methylation-specific blockers. Nucleic Acids Res. 32(1), e10 2004).
    • (2004) Nucleic Acids Res , vol.32 , Issue.1
    • Cottrell, S.E.1    Distler, J.2    Goodman, N.S.3
  • 116
    • 0035866393 scopus 로고    scopus 로고
    • DNA fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells
    • Jahr S, Hentze H, Englisch S et al. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res. 61(4), 1659-1665 (2001).
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1659-1665
    • Jahr, S.1    Hentze, H.2    Englisch, S.3
  • 117
    • 0035875037 scopus 로고    scopus 로고
    • Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients
    • Sozzi G, Conte D, Mariani L et al. Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res. 61(12), 4675-4678 (2001).
    • (2001) Cancer Res , vol.61 , Issue.12 , pp. 4675-4678
    • Sozzi, G.1    Conte, D.2    Mariani, L.3
  • 118
  • 119
    • 0032540905 scopus 로고    scopus 로고
    • A sequencing method based on real-time pyrophosphate
    • Ronaghi M, Uhlen M, Nyren P. A sequencing method based on real-time pyrophosphate. Science 281(5375), 363-365(1998).
    • (1998) Science , vol.281 , Issue.5375 , pp. 363-365
    • Ronaghi, M.1    Uhlen, M.2    Nyren, P.3
  • 120
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat. Med. 10(8), 789-799 (2004).
    • (2004) Nat. Med , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 121
    • 0017360626 scopus 로고
    • Free DNA in the serum of cancer patients and the effect of therapy
    • Leon SA, Shapiro B, Sklaroff DM, Yaros MJ. Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res. 37(3), 646-650 (1977).
    • (1977) Cancer Res , vol.37 , Issue.3 , pp. 646-650
    • Leon, S.A.1    Shapiro, B.2    Sklaroff, D.M.3    Yaros, M.J.4
  • 122
    • 0037146259 scopus 로고    scopus 로고
    • Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer
    • Chang HW, Lee SM, Goodman SN et al. Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer. J. Natl Cancer Inst. 94(22), 1697-1703 (2002).
    • (2002) J. Natl Cancer Inst , vol.94 , Issue.22 , pp. 1697-1703
    • Chang, H.W.1    Lee, S.M.2    Goodman, S.N.3
  • 123
    • 0042173180 scopus 로고    scopus 로고
    • Increased plasma DNA integrity in cancer patients
    • Wang BG, Huang HY, Chen YC et al. Increased plasma DNA integrity in cancer patients. Cancer Res. 63(14), 3966-3968 (2003).
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 3966-3968
    • Wang, B.G.1    Huang, H.Y.2    Chen, Y.C.3
  • 124
    • 8444220925 scopus 로고    scopus 로고
    • Molecular biomarker in prostate cancer: The role of CpG island hypermethylation
    • Bastian PJ, Yegnasubramanian S, Palapattu GS et al. Molecular biomarker in prostate cancer: the role of CpG island hypermethylation. Eur. Urol. 46(6), 698-708 (2004).
    • (2004) Eur. Urol , vol.46 , Issue.6 , pp. 698-708
    • Bastian, P.J.1    Yegnasubramanian, S.2    Palapattu, G.S.3
  • 125
    • 3843106187 scopus 로고    scopus 로고
    • GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer
    • Nakayama M, Gonzalgo ML, Yegnasubramanian S et al. GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer. J. Cell. Biochem. 91(3), 540-552 (2004).
    • (2004) J. Cell. Biochem , vol.91 , Issue.3 , pp. 540-552
    • Nakayama, M.1    Gonzalgo, M.L.2    Yegnasubramanian, S.3
  • 126
    • 33847646837 scopus 로고    scopus 로고
    • Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma
    • Chuang CK, Chu DC, Tzou RD et al. Hypermethylation of the CpG islands in the promoter region flanking GSTP1 gene is a potential plasma DNA biomarker for detecting prostate carcinoma. Cancer Detect. Prev. 31(1), 59-63 (2007).
    • (2007) Cancer Detect. Prev , vol.31 , Issue.1 , pp. 59-63
    • Chuang, C.K.1    Chu, D.C.2    Tzou, R.D.3
  • 127
    • 38349049165 scopus 로고    scopus 로고
    • Promoter hypermethylation in circulating blood cells identifies prostate cancer progression
    • Roupret M, Hupertan V, Catto JW et al. Promoter hypermethylation in circulating blood cells identifies prostate cancer progression. Int. J. Cancer 122(4), 952-956 (2008).
    • (2008) Int. J. Cancer , vol.122 , Issue.4 , pp. 952-956
    • Roupret, M.1    Hupertan, V.2    Catto, J.W.3
  • 128
    • 33750989341 scopus 로고    scopus 로고
    • High concordance of gene methylation in post-digital rectal examination and post-biopsy urine samples for prostate cancer detection
    • Rogers CG, Gonzalgo ML, Yan G et al. High concordance of gene methylation in post-digital rectal examination and post-biopsy urine samples for prostate cancer detection. J. Urol. 176(5), 2280-2284 (2006).
    • (2006) J. Urol , vol.176 , Issue.5 , pp. 2280-2284
    • Rogers, C.G.1    Gonzalgo, M.L.2    Yan, G.3
  • 130
    • 52249118141 scopus 로고    scopus 로고
    • Methylation-specific sequencing of GSTP1 gene promoter in circulating/ extracellular DNA from blood and urine of healthy donors and prostate cancer patients
    • Bryzgunova OE, Morozkin ES, Yarmoschuk SV, Vlassov VV, Laktionov PP. Methylation-specific sequencing of GSTP1 gene promoter in circulating/ extracellular DNA from blood and urine of healthy donors and prostate cancer patients. Ann. NY Acad. Sci. 1137, 222-225 (2008).
    • (2008) Ann. NY Acad. Sci , vol.1137 , pp. 222-225
    • Bryzgunova, O.E.1    Morozkin, E.S.2    Yarmoschuk, S.V.3    Vlassov, V.V.4    Laktionov, P.P.5
  • 132
    • 0142217892 scopus 로고    scopus 로고
    • Ten-year biochemical relapse-free survival after external beam radiation and brachytherapy for localized prostate cancer: The Seattle experience
    • Sylvester JE, Blasko JC, Grimm PD, Meier R, Malmgren JA. Ten-year biochemical relapse-free survival after external beam radiation and brachytherapy for localized prostate cancer: the Seattle experience. Int. J. Radiat. Oncol. Biol. Phys. 57(4), 944-952 (2003).
    • (2003) Int. J. Radiat. Oncol. Biol. Phys , vol.57 , Issue.4 , pp. 944-952
    • Sylvester, J.E.1    Blasko, J.C.2    Grimm, P.D.3    Meier, R.4    Malmgren, J.A.5
  • 133
    • 0037102387 scopus 로고    scopus 로고
    • Comparison of the efficacy of local therapies for localized prostate cancer in the prostate-specific antigen era: A large single-institution experience with radical prostatectomy and external-beam radiotherapy
    • Kupelian PA, Elshaikh M, Reddy CA, Zippe C, Klein EA. Comparison of the efficacy of local therapies for localized prostate cancer in the prostate-specific antigen era: a large single-institution experience with radical prostatectomy and external-beam radiotherapy. J. Clin. Oncol. 20(16), 3376-3385 (2002).
    • (2002) J. Clin. Oncol , vol.20 , Issue.16 , pp. 3376-3385
    • Kupelian, P.A.1    Elshaikh, M.2    Reddy, C.A.3    Zippe, C.4    Klein, E.A.5
  • 134
    • 0142186677 scopus 로고    scopus 로고
    • Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era
    • Kuban DA, Thames HD, Levy LB et al. Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era. Int. J. Radiat. Oncol. Biol. Phys. 57(4), 915-928 (2003).
    • (2003) Int. J. Radiat. Oncol. Biol. Phys , vol.57 , Issue.4 , pp. 915-928
    • Kuban, D.A.1    Thames, H.D.2    Levy, L.B.3
  • 135
    • 33748122712 scopus 로고    scopus 로고
    • Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder
    • discussion: 1361-1352
    • Karakiewicz PI, Shariat SF, Palapattu GS et al. Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder. J. Urol. 176(4 Pt 1), 1354-1361; discussion: 1361-1352 (2006).
    • (2006) J. Urol , vol.176 , Issue.4 PART 1 , pp. 1354-1361
    • Karakiewicz, P.I.1    Shariat, S.F.2    Palapattu, G.S.3
  • 136
    • 0032950295 scopus 로고    scopus 로고
    • Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer
    • Kattan MW, Wheeler TM, Scardino PT. Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer. J. Clin. Oncol. 17(5), 1499-1507 (1999).
    • (1999) J. Clin. Oncol , vol.17 , Issue.5 , pp. 1499-1507
    • Kattan, M.W.1    Wheeler, T.M.2    Scardino, P.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.