Immunoglobulin a nephropathy in China: Progress and challenges

American Journal of Nephrology

Volumn 30, Issue 3, 2009, Pages 268-273

  Cai, Guang Yan ^a   Chen, Xiang Mei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

China; End stage renal disease; Immunoglobulin A; Nephropathy

Indexed keywords

BENAZEPRIL; CILAZAPRIL; CORTICOSTEROID DERIVATIVE; CYCLOPHOSPHAMIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOGLOBULIN A; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; STEROID; UROKINASE;

CLINICAL ASSESSMENT; CLINICAL FEATURE; CLINICAL RESEARCH; CLINICAL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GLOMERULONEPHRITIS; HEMATURIA; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; MALIGNANT HYPERTENSION; MONOTHERAPY; PNEUMONIA; PRIORITY JOURNAL; PROTEINURIA; REVIEW;

CHINA; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOGLOBULIN A; PROGNOSIS;

EID: 66749135244     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000225563     Document Type: Review

References (48)

1. Li LS, Liu ZH: Epidemiologic data of renal diseases from a single unit in China: analysis based on 13,519 renal biopsies. Kidney Int 2004; 66: 920-923.
2. Galla J: IgA nephropathy. Kidney Int 1995; 47: 377-387.
3. Zhou FD, Zhao MH, Zou WZ, Liu G, Wang H: The changing spectrum of primary glomerular diseases within 15 years: a survey of 3,331 patients in a single Chinese centre. Nephrol Dial Transplant 2009; 24: 870-876.
4. Xie Y, Chen X: Epidemiology, major outcomes, risk factors, prevention and management of chronic kidney disease in China. Am J Nephrol 2008; 28: 1-7.
5. Wang HY, Zhang LX, Lv JC: Prevention of the progression of chronic kidney disease: practice in China. Kidney Int 2005; 67:S63-S67.
6. Yuling H, Ruijing X, Xiang J, Yanping J, Lang C, Li L, Dingping Y, Xinti T, Jingyi L, Zhiqing T, Yongyi B, Bing X, Xinxing W, Youxin J, Fox DA, Lundy SK, Guohua D, Jinquan T: CD19 + CD5 + B cells in primary IgA nephropathy. J Am Soc Nephrol 2008; 19: 2130-2139.
7. Zhang JJ, Xu LX, Liu G, Zhao MH, Wang HY: The level of serum secretory IgA of patients with IgA nephropathy is elevated and associated with pathological phenotypes. Nephrol Dial Transplant 2008; 23: 207-212.
8. Gao YH, Xu LX, Zhang JJ, Zhang Y, Zhao MH, Wang HY: Differential binding characteristics of native monomeric and polymeric immunoglobulin A1 (IgA1) on human mesangial cells and the influence of in vitro deglycosylation of IgA1 molecules. Clin Exp Immunol 2007; 148: 507-514.
9. Leung JC, Tang SC, Chan DT, Lui SL, Lai KN: Increased sialylation of polymeric lambda-IgA1 in patients with IgA nephropathy. J Clin Lab Anal 2002; 16: 11-19.
10. Xu LX, Zhao MH: Aberrantly glycosylated serum IgA1 are closely associated with pathologic phenotypes of IgA nephropathy. Kidney Int 2005; 68: 167-172.
11. Zhang JJ, Xu LX, Zhang Y, Zhao MH: Binding capacity of in vitro deglycosylated IgA1 to human mesangial cells. Clin Immunol 2006; 119: 103-109.
12. Lai KN, Chan LY, Tang SC, Tsang AW, Li FF, Lam MF, Lui SL, Leung JC: Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1. Kidney Int 2004; 66: 1403-1416.
13. Yan Y, Xu LX, Zhang JJ, Zhang Y, Zhao MH: Self-aggregated deglycosylated IgA1 with or without IgG were associated with the development of IgA nephropathy. Clin Exp Immunol 2006; 144: 17-24.
14. Ding JX, Xu LX, Lv JC, Zhao MH, Zhang H, Wang HY: Aberrant sialylation of serum IgA1 was associated with prognosis of patients with IgA nephropathy. Clin Immunol 2007; 125: 268-274.
15. Li GS, Zhang H, Lv JC, Shen Y, Wang HY: Variants of C1GALT1 gene are associated with the genetic susceptibility to IgA nephropathy. Kidney Int 2007; 71: 448-453.
16. Pirulli D, Crovella S, Ulivi S, Zadro C, Bertok S, Rendine S, Scolari F, Foramitti M, Ravani P, Roccatello D, Savoldi S, Cerullo G, Lanzilotta SG, Bisceglia L, Zelante L, Floege J, Alexopoulos E, Kirmizis D, Ghiggeri GM, Frascà G, Schena FP, Amoroso A: Genetic variant of C1GalT1 contributes to the susceptibility to IgA nephropathy. J Nephrol 2009; 22: 152-159.
17. Li GS, Zhu L, Zhang H, Lv JC, Ding JX, Zhao MH, Shen Y, Wang HY: Variants of the ST6GALNAC2 promoter influence transcriptional activity and contribute to genetic susceptibility to IgA nephropathy. Hum Mutat 2007; 28: 950-957.
18. Xia Y, Li Y, Du Y, Yang N, Li C, Leung JC, Lam MF, Huang W, Chen S, Maxwell PH, Lai KN, Wang Y: Association of MEGSIN 2093-C-2180T haplotype at the 3 - untranslated region with disease severity and progression of IgA nephropathy. Nephrol Dial Transplant 2006; 21: 1570-1574.
19. Lim CS, Kim SM, Oh YK, Joo KW, Kim YS, Han JS, Kim S: Megsin 2093T-2180C haplotype at the 3 - untranslated region is associated with poor renal survival in Korean IgA nephropathy patients. Clin Nephrol 2008; 70: 101-109.
20. Li G, Zhang H, Lv J, Hou P, Wang H: Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy. Am J Nephrol 2006; 26: 43-49.
21. Xu G, He Q, Shou Z, Wang H, Zhang X, Wang Y, Chen Y, Chen J: NA1/NA2 heterozygote of Fcgr3b is a risk factor for progression of IgA nephropathy in Chinese. J Clin Lab Anal 2007; 21: 298-302.
22. Chow KM, Szeto CC, Lai FM, Poon P, Wong TY, Li PK: Genetic polymorphism of vascular endothelial growth factor: impact on progression of IgA nephropathy. Ren Fail 2006; 28: 15-20.
23. Yong D, Qingqing W, Hua L, Yang LX, Qingling Z, Ying H, Qiaojing Q, Hanchao S: Association of uteroglobin G38A polymorphism with IgA nephropathy: a metaanalysis. Am J Kidney Dis 2006; 48: 1-7.
24. Roos A, van Kooten C: Underglycosylation of IgA in IgA nephropathy: more than a diagnostic marker? Kidney Int 2007; 71: 1089-1091.
25. Moldoveanu Z, Wyatt RJ, Lee JY, Tomana M, Julian BA, Mestecky J, Huang WQ, Anreddy SR, Hall S, Hastings MC, Lau KK, Cook WJ, Novak J: Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int 2007; 71: 1148-1154.
26. Shen P, He L, Jiang Y, Wang C, Chen M: Useful indicators for performing renal biopsy in adult patients with isolated microscopic haematuria. Int J Clin Pract 2007; 61: 789-794.
27. Chen Y, Tang Z, Yang G, Shen S, Yu Y, Zeng C, Chen H, Liu ZH, Li LS: Malignant hypertension in patients with idiopathic IgA nephropathy. Kidney Blood Press Res 2005; 28: 251-258. (Pubitemid 43048615)
28. Jiang L, Zhang JJ, Lv JC, Liu G, Zou WZ, Zhao MH, Zhang H: Malignant hypertension in IgA nephropathy was not associated with background pathological phenotypes of glomerular lesions. Nephrol Dial Transplant 2008; 23: 3921-3927.
29. Wu J, Chen X, Xie Y, Yamanaka N, Shi S, Wu D, Liu S, Cai G: Characteristics and risk factors of intrarenal arterial lesions in patients with IgA nephropathy. Nephrol Dial Transplant 2005; 20: 719-727.
30. Zhang JJ, Jiang L, Liu G, Wang SX, Zou WZ, Zhang H, Zhao MH: Elevation of serum von Willebrand factor and anti-endothelial cell antibodies in patients with immunoglobulin A nephropathy are associated with intrarenal arterial lesions. Nephrology (Carlton) 2008; 13: 712-720.
31. Tang Z, Wu Y, Wang QW, Yu YS, Hu WX, Yao XD, Chen HP, Liu ZH, Li LS: Idiopathic IgA nephropathy with diffuse crescent formation. Am J Nephrol 2002; 22: 480-486.
32. Lai KN, Chan LY, Leung JC: Mechanisms of tubulointerstitial injury in IgA nephropathy. Kidney Int Suppl 2005; 94:S110-S115.
33. Ding H, He Y, Li K, Yang J, Li X, Lu R, Gao W: Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy. Clin Immunol 2007; 123: 227-234.
34. Lv J, Zhang H, Zhou Y, Li G, Zou W, Wang H: Natural history of immunoglobulin A nephropathy and predictive factors of prognosis: a long-term follow up of 204 cases in China. Nephrology (Carlton) 2008; 13: 242-246.
35. Li PK, Ho KK, Szeto CC, Yu L, Lai FM: Prognostic indicators of IgA nephropathy in the Chinese - clinical and pathological perspectives. Nephrol Dial Transplant 2002; 17: 64-69.
36. Shen P, He L, Huang D: Clinical course and prognostic factors of clinical early IgA nephropathy. Neth J Med 2008; 66: 242-247.
37. Reich HN, Troyanov S, Scholey JW, Cattran DC: Remission of proteinuria improves prognosis in IgA nephropathy. J Am Soc Nephrol 2007; 18: 3177-3183.
38. Chen Y, Tang Z, Wang Q, Yu Y, Zeng C, Chen H, Liu ZH, Li LS: Long-term efficacy of tonsillectomy in Chinese patients with IgA nephropathy. Am J Nephrol 2007; 27: 170-175.
39. Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Kitamura K: Effect of tonsillectomy plus steroid pulse therapy on clinical remission of IgA nephropathy: a controlled study. Clin J Am Soc Nephrol 2008; 3: 1301-1307.
40. Chen X, Qiu Q, Tang L, Liu S, Cai G, Liu H, Xie Y: Effects of co-administration of urokinase and benazepril on severe IgA nephropathy. Nephrol Dial Transplant 2004; 19: 852-857.
41. Kobayashi Y, Hiki Y, Kokubo T, Horii A, Tateno S: Steroid therapy during the early stage of progressive IgA nephropathy: a 10-year follow up study. Nephron 1996; 72: 237-242.
42. Pozzi C, Andrulli S, Del Vecchio L, Melis P, Fogazzi GB, Altieri P, Ponticelli C, Locatelli F: Corticosteroids effectiveness in IgA nephropathy: long-term results of a randomized, controlled trial. J Am Soc Nephrol 2004; 15: 157-163.
43. Lv J, Zhang H, Chen Y, Li G, Jiang L, Singh AK, Wang H: Combination therapy of prednisone and ACE inhibitor versus ACE-inhibitor therapy alone in patients with IgA nephropathy: a randomized controlled trial. Am J Kidney Dis 2009; 53: 26-32.
44. Chen X, Chen P, Cai G, Wu J, Cui Y, Zhang Y, Liu S, Tang L: A randomized control trial of mycophenolate mofetil treatment in severe IgA nephropathy (in Chinese). Zhonghua Yi Xue Za Zhi 2002; 82: 796-801.
45. Tang S, Leung JC, Chan LY, Lui YH, Tang CS, Kan CH, Ho YW, Lai KN: Mycophenolate mofetil alleviates persistent proteinuria in IgA nephropathy. Kidney Int 2005; 68: 802-812.
46. Xu G, Tu W, Jiang D, Xu C: Mycophenolate mofetil treatment for IgA nephropathy: a meta-analysis. Am J Nephrol 2008; 29: 362-367.
47. Lv J, Zhang H, Cui Z, Su T, Zhang Y, Wang H: Delayed severe pneumonia in mycophenolate mofetil-treated patients with IgA nephropathy. Nephrol Dial Transplant 2008;23: 2868-2872.
48. Tumlin JA, Lohavichan V, Hennigar R: Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide. Nephrol Dial Transplant 2003; 18: 1321-1329.