Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin a nephropathy

American Journal of Nephrology

Volumn 26, Issue 1, 2006, Pages 43-49

  Li, Guisen ^a   Zhang, Hong ^a   Lv, Jicheng ^a   Hou, Ping ^a   Wang, Haiyan ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Immunoglobulin A nephropathy; MUC20 gene; Variable number of tandem repeats polymorphism

Indexed keywords

MUCIN; MUCIN 20; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CHINESE; CLINICAL FEATURE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; FOLLOW UP; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HIGH RISK PATIENT; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD; TANDEM REPEAT; VARIABLE NUMBER OF TANDEM REPEAT;

ADOLESCENT; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHINA; DISEASE PROGRESSION; FEMALE; GENOTYPE; GLOMERULONEPHRITIS, IGA; HUMANS; MALE; MIDDLE AGED; MUCINS; POLYMORPHISM, GENETIC; TANDEM REPEAT SEQUENCES;

EID: 33645656073     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091785     Document Type: Article

References (25)

1. D'Amico G: Natural history of idiopathic IgA nephropathy and factors predictive of disease outcome. Semin Nephrol 2004:24:179-196.
2. Levy M, Berger J: Worldwide perspective of IgA nephropathy. Am J Kidney Dis 1988:12:340-347.
3. Hsu SI, Ramirez SB, Winn MP, Bonventre JV, Owen WF: Evidence for genetic factors in the development and progression of IgA nephropathy. Kidney Int 2000:57:1818-1835.
4. Higuchi T, Orita T, Nakanishi S, Katsuya K, Watanabe H, Yamasaki Y, Waga I, Nanayama T, Yamamoto Y, Munger W, Sun HW, Falk RJ, Jennette JC, Alcorta DA, Li H, Yamamoto T, Saito Y, Nakamura M: Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney. J Biol Chem 2004:279:1968-1979.
5. Waga I, Yamamoto J, Sasai H, Munger WE, Hogan SL, Preston GA, Sun HW, Jennette JC, Falk RJ, Alcorta DA: Altered mRNA expression in renal biopsy tissue from patients with IgA nephropathy. Kidney Int 2003;64:1253-1264.
6. Levey AS, Greene T, Kusek JW, Beck GL, MDRD Study Group: A simplified equation to predict glomerular filtration rate from serum creatinine (abstract). J Am Soc Nephrol 2000;11:155A.
7. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D: A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-470.
8. Wyatt RJ, Emancipator SN, Kon V, Waldo FB, Donadio J, Grande JP, Andreoli SP, Glassock RJ: IgA nephropathy databank: development of a system for management of renal biopsy acquired data. Am J Kidney Dis 1997;29:817-828.
9. Haas M: Histologic subclassification of IgA nephropathy: a clinicopathologic study of 244 cases. Am J Kidney Dis 1997;29:829-842.
10. Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
11. Carvalho F, Seraca R, David L, Amorim A, Seixas M, Bennett E, Clausen H, Sobrinho-Simoes M: MUC1 gene polymorphism and gastric cancer - an epidemiological study. Glycoconj J 1997;14:107-111.
12. Barratt J, Feehally J, Smith AC: Pathogenesis of IgA nephropathy. Semin Nephrol 2004;24:197-217.
13. Narita I, Alchi B, Sato F, Saga D, Ogawa A, Tsubata Y, Kondo D, Sakatsume M, Yamamoto T, Gejyo F: Up-regulation in the kidney and its genetic polymorphism of MUC20, a regulator of Met signaling cascade, in patients with IgA nephropathy. Kidney Int 2005;68:1970.
14. Dekker J, Rossen JW, Buller HA, Einerhand AW: The MUC family: an obituary. Trends Biochem Sci 2002;27:126-131.
15. Hollingsworth MA, Swanson BJ: Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004;4:45-60.
16. Debailleul V, Laine A, Huet G, Mathon P, d'Hooghe MC, Aubert JP, Porchet N: Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs. J Biol Chem 1998;273:881-890.
17. Suva F, Carvalho F, Peixoto A, Seixas M, Almeida R, Carneiro F, Mesquita P, Figueiredo C, Nogueira C, Swallow DM, Amorim A, David L: MUC1 gene polymorphism in the gastric carcinogenesis pathway. Eur J Hum Genet 2001;9:548-552.
18. Silva F, Carvalho F, Peixoto A, Teixeira A, Almeida R, Reis C, Bravo LE, Realpe L, Correa P, David L: MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritis. Eur J Hum Genet 2003;11:380-384.
19. Kirkbride HJ, Bolscher JG, Nazmi K, Vinall LE, Nash MW, Moss FM, Mitchell DM, Swallow DM: Genetic polymorphism of MUC7: allele frequencies and association with asthma. Eur J Hum Genet 2001;9:347-354.
20. McIntire JJ, Umetsu DT, DeKruyff RH: TIM-1, a novel allergy and asthma susceptibility gene. Springer Semin Immunopathol 2004;25:335-348.
21. Vinall LE, Fowler JC, Jones AL, Kirkbride HJ, de Bolos C, Laine A, Porchet N, Gum JR, Kim YS, Moss FM, Mitchell DM, Swallow DM: Polymorphism of human mucin genes in chest disease: possible significance of MUC2. Am J Respir Cell Mol Biol 2000;23:678-686.
22. Verstrepen VJ, Jansen A, Lewitter F, Fink GR: Intragenic tandem repeats generate functional variability. Nat Genet 2005;37:986-990.
23. Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M: Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem 1998;273:4135-4142.
24. Leroy X, Copin MC, Devisme L, Buisine MP, Aubert JP, Gosselin B, Porchet N: Expression of human mucin genes in normal kidney and renal cell carcinoma. Histopathology 2002;40:450-457.
25. Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV: Kidney injury molecule-1 : a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol 2004;286:F552-F563.