Malignant hypertension in IgA nephropathy was not associated with background pathological phenotypes of glomerular lesions

Nephrology Dialysis Transplantation

Volumn 23, Issue 12, 2008, Pages 3921-3927

  Jiang, Lei ^a   Zhang, Jun Jun ^a   Lv, Ji Cheng ^a   Liu, Gang ^a   Zou, Wan Zhong ^a   Zhao, Ming Hui ^a   Zhang, Hong ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Anti endothelial cell antibodies; IgA nephropathy; Malignant hypertension; Pathology

Indexed keywords

CREATININE; ENDOTHELIAL CELL ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ADULT; ARTICLE; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; FEMALE; GLOMERULOSCLEROSIS; HISTOPATHOLOGY; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; MAJOR CLINICAL STUDY; MALE; MALIGNANT HYPERTENSION; PHENOTYPE; PRIORITY JOURNAL; PROTEINURIA; WESTERN BLOTTING;

AGED; AUTOANTIBODIES; AUTOANTIGENS; CASE-CONTROL STUDIES; CELLS, CULTURED; ENDOTHELIAL CELLS; FEMALE; GLOMERULONEPHRITIS, IGA; HUMANS; HYPERTENSION, MALIGNANT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PHENOTYPE; PROGNOSIS;

EID: 56749177359     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfn371     Document Type: Article

References (21)

1. Chen Y, Tang Z, Yang G et al. Malignant hypertension in patients with idiopathic IgA nephropathy. Kidney Blood Press Res 2005; 28: 251-258
2. Cheng XY, Zhao MH, Li XM et al. Clinical features and prognostic factors of chronic glomerulonephritis with malignant hypertension. Chin J Nephrol 2004; 20: 79-82
3. Zhou FD, Liu YC, Zou WZ et al. Malignant hypertension presenting with renal damage: a clinical and pathological analyses. Chin J Intern Med 2001; 40: 165-168
4. Yu SH, Whitworth JA, Kincaid-Smith PS. Malignant hypertension: aetiology and outcome in 83 patients. Clin Exp Hypertens A 1986; 8: 1211-1230
5. Clarkson AR, Seymour AE, Thompson AJ et al. IgA nephropathy: a syndrome of uniform morphology, diverse clinical features and uncertain prognosis. Clin Nephrol 1977; 8: 459-471
6. Fornasieri A, Pinerolo C, Bernasconi P et al. Anti-mesangial and anti-endothelial cell antibodies in IgA mesangial nephropathy. Clin Nephrol 1995; 44: 71-79
7. Wang MX, Walker RG, Kincaid-Smith P. Clinicopathologic associations of anti-endothelial cell antibodies in immunoglobulin A nephropathy and lupus nephritis. Am J Kidney Dis 1993; 22: 378-386
8. Frampton G, Walker RG, Perry GJ et al. IgA affinity to ssDNA or endothelial cells and its deposition in glomerular capillary walls in IgA nephropathy. Nephrol Dial Transplant 1990; 5: 841-846
9. Yap HK, Sakai RS, Bahn L et al. Anti-vascular endothelial cell antibodies in patients with IgA nephropathy: frequency and clinical significance. Clin Immunol Immunopathol 1988; 49: 450-462
10. Frampton G, Jayne DR, Perry GJ et al. Autoantibodies to endothelial cells and neutrophil cytoplasmic antigens in systemic vasculitis. Clin Exp Immunol 1990; 82: 227-232
11. Cines DB, Lyss AP, Reeber M et al. Presence of complement-fixing anti-endothelial cell antibodies in systemic lupus erythematosus. J Clin Invest 1984; 73: 611-625
12. Kitiyakara C and Guzman NJ. Malignant hypertension and hypertensive emergencies. J Am Soc Nephrol 1998; 9: 133-142
13. Beutler JJ and Koomans HA. Malignant hypertension: still a challenge. Nephrol Dial Transplant 1997; 12: 2019-2023
14. Haas M. Histologic subclassification of IgA nephropathy: a clinicopathologic study of 244 cases. Am J Kidney Dis 1997; 29: 829-842
15. Katafuchi R, Kiyoshi Y, Oh Y et al. Glomerular score as a prognosticator in IgA nephropathy: its usefulness and limitation. Clin Nephrol 1998; 49: 1-8
16. To KF, Choi PC, Szeto CC et al. Outcome of IgA nephropathy in adults graded by chronic histological lesions. Am J Kidney Dis 2000; 35: 392-400
17. Yu F, Zhao MH, Zhang YK et al. Anti-endothelial cell antibodies (AECA) in patients with propylthiouracil (PTU)-induced ANCA positive vasculitis are associated with disease activity. Clin Exp Immunol 2005; 139: 569-574
18. Kawazoe N, Eto T, Abe I et al. Long-term prognosis of malignant hypertension; difference between underlying diseases such as essential hypertension and chronic glomerulonephritis. Clin Nephrol 1988; 29: 53-57
19. Dieude M, Senecal JL, Raymond Y. Induction of endothelial cell apoptosis by heat-shock protein 60-reactive antibodies from antiendothelial cell autoantibody-positive systemic lupus erythematosus patients. Arthritis Rheum 2004; 50: 3221-3231
20. Carvalho D, Savage CO, Isenberg D et al. IgG anti-endothelial cell autoantibodies from patients with systemic lupus erythematosus or systemic vasculitis stimulate the release of two endothelial cell-derived mediators, which enhance adhesion molecule expression and leukocyte adhesion in an autocrine manner. Arthritis Rheum 1999; 42: 631-640
21. Papa ND, Raschi E, Moroni G et al. Anti-endothelial cell IgG fractions from systemic lupus erythematosus patients bind to human endothelial cells and induce a pro-adhesive and a pro-inflammatory phenotype in vitro. Lupus 1999; 8: 423-429