CD19+CD5+ B cells in primary IgA nephropathy

Journal of the American Society of Nephrology

Volumn 19, Issue 11, 2008, Pages 2130-2139

  Yuling, He ^a,b   Ruijing, Xiao ^a,b   Xiang, Ji ^a,b   Yanping, Jiang ^a   Lang, Chen ^a,b   Li, Li ^a,b   Dingping, Yang ^b   Xinti, Tan ^a   Jingyi, Liu ^a   Zhiqing, Tang ^a,d   Yongyi, Bi ^a   Bing, Xia ^c   Xinxing, Wu ^a   Youxin, Jin ^d   Fox, David A ^a,e   Lundy, Steven K ^a,e   Guohua, Ding ^b,f   Jinquan, Tan ^a  

^a WUHAN UNIVERSITY   (China)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^d Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD5 ANTIGEN; CORTICOSTEROID; CYTOKINE; FAS LIGAND; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOSUPPRESSIVE AGENT; PRIMER DNA;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; BLOOD; CD19+ CD5+ B CELL; CELL ISOLATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG RESPONSE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN PRODUCTION; KIDNEY BIOPSY; PERITONEAL FLUID; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SYSTEMIC LUPUS ERYTHEMATOSUS; ADOLESCENT; ADULT; BIOSYNTHESIS; CASE CONTROL STUDY; CELL DIFFERENTIATION; FEMALE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ADOLESCENT; ADULT; ANTIGENS, CD19; ANTIGENS, CD5; APOPTOSIS; B-LYMPHOCYTE SUBSETS; BASE SEQUENCE; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; DNA PRIMERS; FEMALE; GLOMERULONEPHRITIS, IGA; HUMANS; INTERFERON TYPE II; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED;

EID: 55749097064     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2007121303     Document Type: Article

References (46)

1. Donadio JV, Grande JP: IgA nephropathy. N Engl J Med 347: 738-748, 2002
2. Levy M, Berger J: Worldwide perspective of IgA nephropathy. Am J Kidney Dis 12: 340-347, 1988
3. Radford MG Jr, Donadio JV Jr, Bergstralh EJ, Grande JP: Predicting renal outcome in IgA nephropathy. J Am Soc Nephrol 8: 199-207, 1997
4. Emancipator SN: IgA nephropathy: Morphologic expression and pathogenesis. Am J Kidney Dis 23: 451-462, 1994
5. Montecino-Rodriguez E, Dorshkind K: New perspectives in B-1 B cell development and function. Trends Immunol 27: 428-433, 2006
6. Hayakawa K, Hardy RR: Development and function of B-1 cells. Curr Opin Immunol 12: 346-354, 2000
7. Su I-h, Tarakhovsky A: B-1 cells: Orthodox or conformist? Curr Opin Immunol 12: 191-194, 2000
8. Berland R, Wortis HH: Origins and functions of B-1 cells with notes on the role of CD5. Annu Rev Immunol 20: 253-300, 2002
9. Haas KM, Poe JC, Steeber DA, Tedder TF: B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. Immunity 23: 7-18, 2005
10. Schoenbeck S, McKenzie DT, Kagnoff MF: Interleukin 5 is a differentiation factor for IgA B cells. Eur J Immunol 19: 965-969, 1989
11. Kim PH, Eckmann L, Lee WJ, Han W, Kagnoff MF: Cholera toxin and cholera toxin B subunit induce IgA switching through the action of TGF-beta 1. J Immunol 160: 1198-1203, 1998
12. Tumang JR, Frances R, Yeo SG, Rothstein TL: Cutting edge: Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors. J Immunol 174: 3173-3177, 2005
13. Macpherson A, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM: A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 288: 2222-2226, 2000
14. Kunisawa J, Kurashima Y, Gohda M, Higuchi M, Ishikawa I, Miura F, Ogahara I, Kiyono H: Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production. Blood 109: 3749-3756, 2007
15. Duan B, Morel L: Role of B-1a cells in autoimmunity. Autoimmun Rev 5: 403-408, 2006
16. Watanabe N, Ikuta K, Nisitani S, Chiba T, Honjo T: Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice. J Exp Med 196: 141-146, 2002
17. Kodama S, Suzuki M, Arita M, Mogi G: Increase in tonsillar germinal centre B-1 cell numbers in IgA nephropathy (IgAN) patients and reduced susceptibility to Fas-mediated apoptosis. Clin Exp Immunol 123: 301-308, 2001
18. Donadio JV, Bergstralh EJ, Offord KP, Holley KE, Spencer DC, Mayo Nephrology Collaborative Group: Clinical and histopathologic associations with impaired renal function in IgA nephropathy. Clin Nephrol 41: 65-71, 1994
19. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ: The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25: 1271-1277, 1982
20. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH: Derivation of the SLEDAI: A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 35: 630-640, 1992
21. Kotzin BL: Systemic lupus erythematosus. Cell 85: 303-306, 1996
22. Martin F: Kearney JF: B1 cells: Similarities and differences with other B cell subsets. Curr Opin Immunol 13: 195-201, 2001
23. Rolink AG, Melchers F: BAFFled B cells survive and thrive: Roles of BAFF in B-cell development. Curr Opin Immunol 14: 266-275, 2002
24. Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK: Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16: 219-230, 2002
25. Mauri C, Gray D, Mushtaq N, Londei M: Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197: 489-501, 2003
26. Harris DP, Haynes L, Sayles PC, Duso DK, Eaton SM, Lepak NM, Johnson LL, Swain SL, Lund FE: Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat Immunol 1: 475-482, 2000
27. Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM: B cells regulate autoimmunity by provision of IL-10. Nat Immunol 3: 944-950, 2002
28. Lund FE, Garvy BA, Randall TD, Harris DP: Regulatory roles for cytokine-producing B cells in infection and autoimmune disease. Curr Dir Autoimmun 8: 25-54, 2005
29. + T cells. J Immunol 179: 2880-2888, 2007
30. Dauphinee M, Tovar Z, Talal N: B cells expressing CD5 are increased in Sjogren's syndrome. Arthritis Rheum 31: 642-647, 1988
31. Youinou P, Mackenzie L, Katsikis P, Merdrignac G, Isenberg DA, Tuaillon N, Lamour A, Le Goff P, Jouquan J, Drogou A, et al.: The relationship between CD5-expressing B lymphocytes and serologic abnormalities in rheumatoid arthritis patients and their relatives. Arthritis Rheum 33: 339-348, 1990
32. Murakami M, Tsubata T, Okamoto M, Shimizu A, Kumagai S, Imura H, Honjo T: Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature 357: 77-80, 1992
33. Andrews BS, Eisenberg RA, Theofilopoulos AN, Izui S, Wilson CB, McConahey PJ, Murphy ED, Roths JB, Dixon FJ: Spontaneous murine lupus-like syndromes: Clinical and immunopathological manifestations in several strains. J Exp Med 148: 1198-1215, 1978
34. Reap EA, Sobel ES, Cohen PL, Eisenberg RA: Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice. J Exp Med 177: 69-78, 1993
35. Kataoka K, Fujihashi K, Sekine S, Fukuiwa T, Kobayashi R, Suzuki H, Nagata H, Takatsu K, Shizukuishi S, McGhee JR, Fujihashi K: Nasal cholera toxin elicits IL-5 and IL-5 receptor alpha-chain expressing B-1a B cells for innate mucosal IgA antibody responses. J Immunol 178: 6058-6065, 2007
36. Fagarasan S, Honjo T: T-Independent immune response: New aspects of B cell biology. Science 290: 89-92, 2000
37. Hardy RR: B-1 B cells: Development, selection, natural autoantibody and leukemia. Curr Opin Immunol 18: 547-555, 2006
38. Tumang JR, Hastings WD, Bai C, Rothstein TL: Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics. Eur J Immunol 34: 2158-2167, 2004
39. Fischer M, Klein U, Kuppers R: Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vκ genes lacking somatic mutation. J Clin Invest 100: 1667-1676, 1997
40. Youinou P, Jamin C, Lydyard PM: CD5 expression in human B-cell populations. Immunol Today 20: 312-316, 1999
41. Keel M, Trentz O: Pathophysiology of polytrauma. Injury 36: 691-709, 2005
42. Hill GS, Delahousse M, Nochy D, Tomkiewicz E, Rémy P, Mignon F, Méry JP: A new morphologic index for the evaluation of renal biopsies in lupus nephritis. Kidney Int 58: 1160-1173, 2000
43. + B cells. J Immunol 177: 6713-6722, 2006
44. Chalmers IM, Janossy G, Contreras M, Navarrete C: Intracellular cytokine profile of cord and adult blood lymphocytes. Blood 92: 11-18, 1998
45. Jinquan T, Quan S, Jacobi HH, Jing C, Millner A, Jensen B, Madsen HO, Ryder LP, Svejgaard A, Malling HJ, Skov PS, Poulsen LK: CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: Chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma. Blood 96: 1230-1238, 2000
46. Mueller A, Kelly E, Strange PG: Pathways for internalization and recycling of the chemokine receptor CCR5. Blood 99: 785-791, 2002