The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 6, 2009, Pages

  Arndt, Mary Ann ^a,d   Battaglia, Valentina ^e   Parisi, Eva ^f   Lortie, Mark J ^a,d   Isome, Masato ^g   Baskerville, Christopher ^d   Pizzo, Donald P ^c,d   Ientile, Riccardo ^h   Colombatto, Sebastiano ⁱ   Toninello, Antonio ^e   Satriano, Joseph ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e UNIVERSITY OF PADOVA   (Italy)

^f HOSPITAL UNIVERSITARI ARNAU DE VILANOVA   (Spain)

^g FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^h UNIVERSITY OF MESSINA   (Italy)

ⁱ UNIVERSITY OF TURIN   (Italy)

Author keywords

Bcl 2; Caspase 3; Free radical scavenger; Oxidative stress; Polyamines

Indexed keywords

AGMATINE; CAMPTOTHECIN; CASPASE 3; FLUOROURACIL; HYDROGEN PEROXIDE; PROTEIN BCL 2; THIOL DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGMATINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ARGININE; CALCIUM; CAMPTOTHECIN; CASPASE 3; CELL PROLIFERATION; CYTOPROTECTION; DNA FRAGMENTATION; FLUOROURACIL; KIDNEY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL SWELLING; NIH 3T3 CELLS; POLYAMINES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

EID: 66749106228     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00529.2008     Document Type: Article

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