The cataract-associated R14C mutant of human γD-crystallin shows a variety of intermolecular disulfide cross-links: A raman spectroscopic study

Biochemistry

Volumn 48, Issue 22, 2009, Pages 4937-4945

  Pande, Ajay ^a   Gillot, Darnelle ^a,b   Pande, Jayanti ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b MANSFIELD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIN; CYSTEINE RESIDUES; DIHEDRAL ANGLES; EXCHANGE REACTION; INITIATING EVENTS; LONG-TERM STORAGE; OXIDATIVE DEGRADATION; PHYSIOLOGICAL PH; PROTEIN CROSS-LINK; PROTEIN PRECIPITATION; RAMAN BANDS; RAMAN DATA; RAMAN SPECTROSCOPIC STUDY; RAPID OXIDATION;

CHEMICAL REACTIONS; PH EFFECTS; RAMAN SPECTROSCOPY;

SPECTROSCOPIC ANALYSIS;

GAMMA CRYSTALLIN; HUMAN GAMMAD CRYSTALLIN; THIOL; UNCLASSIFIED DRUG;

ARTICLE; CATARACT; DISULFIDE BOND; GENE MUTATION; MOLECULAR MODEL; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RAMAN SPECTROMETRY;

AMINO ACID SUBSTITUTION; ARGININE; CATARACT; CROSS-LINKING REAGENTS; CRYSTALLINS; CYSTEINE; DISULFIDES; HUMANS; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS, RAMAN; SULFHYDRYL COMPOUNDS;

EID: 66649096748     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9004182     Document Type: Article

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