Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through Gαq and downstream calcineurin signaling in myocardial cells

Endocrinology

Volumn 150, Issue 6, 2009, Pages 2723-2731

  Chu, Chun Hsien ^a   Tzang, Bor Show ^a   Chen, Li Mien ^b,c   Liu, Chung Jung ^d   Tsai, Fuu Jen ^d   Tsai, Chang Hai ^e   Lin, James A ^d   Kuo, Wei Wen ^d   Bau, Da Tian ^d   Yao, Chun Hsu ^d   Huang, Chih Yang ^d,e  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA Q POLYPEPTIDE; CALCINEURIN; POLYPEPTIDE; SHORT HAIRPIN RNA; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; HEART MITOCHONDRION; HEART MUSCLE CELL; NEWBORN; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CALCINEURIN; CELLS, CULTURED; CYTOCHROMES C; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MITOCHONDRIA, HEART; MODELS, ANIMAL; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, IGF TYPE 2; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 66649095587     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0975     Document Type: Article

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