메뉴 건너뛰기




Volumn 29, Issue 11, 2009, Pages 2207-2216

Involvement of hypothalamic peptides in the anorectic action of the CB 1 receptor antagonist rimonabant (SR 141716)

Author keywords

Appetite; C fos; Endocannabinoid; Hypothalamus; Peptides; Rimonabant

Indexed keywords

ALPHA INTERMEDIN; BRAIN PEPTIDE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; MELANIN CONCENTRATING HORMONE; MESSENGER RNA; OREXIN; PROTEIN FOS; RIMONABANT;

EID: 66449135959     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2009.06750.x     Document Type: Article
Times cited : (37)

References (52)
  • 1
    • 0032926695 scopus 로고    scopus 로고
    • The effects of cannabinoids on the brain
    • DOI 10.1016/S0301-0082(98)00087-2, PII S0301008298000872
    • Ameri, A. (1999) The effects of cannabinoids on the brain. Prog. Neurobiol., 58, 315 348. (Pubitemid 29230000)
    • (1999) Progress in Neurobiology , vol.58 , Issue.4 , pp. 315-348
    • Ameri, A.1
  • 3
    • 0036460171 scopus 로고    scopus 로고
    • Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: Focus on orexin targets involved in control of food and water intake
    • DOI 10.1046/j.0953-816x.2001.01859.x
    • Backberg, M., Hervieu, G., Wilson, S. Meister, B. (2002) Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake. Eur. J. Neurosci., 15, 315 328. (Pubitemid 35471953)
    • (2002) European Journal of Neuroscience , vol.15 , Issue.2 , pp. 315-328
    • Backberg, M.1    Hervieu, G.2    Wilson, S.3    Meister, B.4
  • 4
    • 0142116115 scopus 로고    scopus 로고
    • Acute food deprivation and chronic food restriction differentially affect hypothalamic NPY mRNA expression
    • Bi, S., Robinson, B.M. Moran, T.H. (2003) Acute food deprivation and chronic food restriction differentially affect hypothalamic NPY mRNA expression. Am. J. Physiol. Regul. Integr. Comp. Physiol., 285, R1030 1036.
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.285 , pp. 1030-1036
    • Bi, S.1    Robinson, B.M.2    Moran, T.H.3
  • 5
    • 0032541111 scopus 로고    scopus 로고
    • Appetite suppression and weight loss after the cannabinoid antagonist SR141716
    • Colombo, G., Agabio, R., Diaz, G., Lobina, C., Reali, R. Gessa, G.L. (1998) Appetite suppression and weight loss after the cannabinoid antagonist SR141716. Life Sci., 63, PL113 PL117.
    • (1998) Life Sci. , vol.63
    • Colombo, G.1    Agabio, R.2    Diaz, G.3    Lobina, C.4    Reali, R.5    Gessa, G.L.6
  • 7
    • 37449022894 scopus 로고    scopus 로고
    • Pretreatment with subeffective doses of rimonabant attenuates orexigenic actions of orexin A-hypocretin 1
    • Crespo, I., Gómez de Heras, R., Rodríguez de Fonseca, F. Navarro, M. (2008) Pretreatment with subeffective doses of rimonabant attenuates orexigenic actions of orexin A-hypocretin 1. Neuropharmacology, 54, 219 225.
    • (2008) Neuropharmacology , vol.54 , pp. 219-225
    • Crespo, I.1    Gómez De Heras, R.2    Rodríguez De Fonseca, F.3    Navarro, M.4
  • 9
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • DOI 10.1056/NEJMoa044537
    • Despres, J.P., Golay, A. Sjostrom, L. (2005) Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N. Engl. J. Med., 353, 2121 2134. (Pubitemid 41653104)
    • (2005) New England Journal of Medicine , vol.353 , Issue.20 , pp. 2121-2134
    • Despres, J.-P.1    Golay, A.2    Sjostrom, L.3
  • 12
    • 23944487985 scopus 로고    scopus 로고
    • Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus
    • DOI 10.1016/j.neuropharm.2005.04.017, PII S0028390805001668
    • Gamber, K.M., Macarthur, H. Westfall, T.C. (2005) Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. Neuropharmacology, 49, 646 652. (Pubitemid 41208286)
    • (2005) Neuropharmacology , vol.49 , Issue.5 , pp. 646-652
    • Gamber, K.M.1    Macarthur, H.2    Westfall, T.C.3
  • 13
    • 0023034795 scopus 로고
    • Stimulation of neuronal acetylcholine receptors induces rapid gene transcription
    • Greenberg, M.E., Ziff, E.B. Greene, L.A. (1986) Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science, 234, 80 83. (Pubitemid 17171550)
    • (1986) Science , vol.234 , Issue.4772 , pp. 80-83
    • Greenberg, M.E.1    Ziff, E.B.2    Greene, L.A.3
  • 14
    • 25644432796 scopus 로고    scopus 로고
    • A role for lateral hypothalamic orexin neurons in reward seeking
    • DOI 10.1038/nature04071, PII N04071
    • Harris, G.C., Wimmer, M. Aston-Jones, G. (2005) A role for lateral hypothalamic orexin neurons in reward seeking. Nature, 437, 556 559. (Pubitemid 41613553)
    • (2005) Nature , vol.437 , Issue.7058 , pp. 556-559
    • Harris, G.C.1    Wimmer, M.2    Aston-Jones, G.3
  • 15
    • 0025954862 scopus 로고
    • Characterization and localization of cannabiniod receptors in rat brain: A quantitative in vitro autoradiographic study
    • Herkenham, M., Lynn, A.B., Johnson, M.R., Melvin, L.S., de Costa, B.R. Rice, K.C. (1991) Characterization and localization of cannabiniod receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci., 11, 563 583.
    • (1991) J. Neurosci. , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 16
    • 34247895688 scopus 로고    scopus 로고
    • Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: Implications for cannabinoid actions on food intake and cognitive arousal
    • Huang, H., Acuna-Goycolea, C., Li, Y., Cheng, H.M., Obrietan, K. van den Pol, A.N. (2007) Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: implications for cannabinoid actions on food intake and cognitive arousal. J. Neurosci., 27, 4870 4871.
    • (2007) J. Neurosci. , vol.27 , pp. 4870-4871
    • Huang, H.1    Acuna-Goycolea, C.2    Li, Y.3    Cheng, H.M.4    Obrietan, K.5    Van Den Pol, A.N.6
  • 17
    • 0035185205 scopus 로고    scopus 로고
    • Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
    • Jamshidi, N. Taylor, D.A. (2001) Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. Br. J. Pharmacol., 134, 1151 1154. (Pubitemid 33097243)
    • (2001) British Journal of Pharmacology , vol.134 , Issue.6 , pp. 1151-1154
    • Jamshidi, N.1    Taylor, D.A.2
  • 18
    • 0035984946 scopus 로고    scopus 로고
    • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
    • Kirkham, T.C., Williams, C.M., Fezza, F. Di Marzo, V. (2002) Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br. J. Pharmacol., 136, 550 557. (Pubitemid 34717699)
    • (2002) British Journal of Pharmacology , vol.136 , Issue.4 , pp. 550-557
    • Kirkham, T.C.1    Williams, C.M.2    Fezza, F.3    Di Marzo, V.4
  • 21
    • 0028854983 scopus 로고
    • C-fos expression in the paraventricular nucleus of the hypothalamus following intracerebroventricular infusions of neuropeptide y
    • Lambert, P.D., Phillips, P.J., Wilding, J.P., Bloom, S.R. Herbert, J. (1995) c-fos expression in the paraventricular nucleus of the hypothalamus following intracerebroventricular infusions of neuropeptide Y. Brain Res., 670, 59 65.
    • (1995) Brain Res. , vol.670 , pp. 59-65
    • Lambert, P.D.1    Phillips, P.J.2    Wilding, J.P.3    Bloom, S.R.4    Herbert, J.5
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K.J. Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402 408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 33645517680 scopus 로고    scopus 로고
    • Endogenous cannabinoids in the brain and peripheral tissues: Regulation of their levels and control of food intake
    • Matias, I., Bisogno, T. Di Marzo, V. (2006) Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. Int. J. Obes. (Lond), 30 (Suppl. 1 S7 S12.
    • (2006) Int. J. Obes. (Lond) , vol.30 , Issue.SUPPL. 1
    • Matias, I.1    Bisogno, T.2    Di Marzo, V.3
  • 27
    • 33645532673 scopus 로고    scopus 로고
    • The role of the endocannabinoid system in the control of energy homeostasis
    • Osei-Hyiaman, D., Harvey-White, J. Bátkai, S.K.G. (2006) The role of the endocannabinoid system in the control of energy homeostasis. Int. J. Obes. (Lond), 30 (Suppl. 1 S33 S38.
    • (2006) Int. J. Obes. (Lond) , vol.30 , Issue.SUPPL. 1
    • Osei-Hyiaman, D.1    Harvey-White, J.2    Bátkai, S.K.G.3
  • 28
    • 33845874637 scopus 로고    scopus 로고
    • Drug treatments for obesity: orlistat, sibutramine, and rimonabant
    • DOI 10.1016/S0140-6736(07)60033-6, PII S0140673607600336
    • Padwal, R.S. Majumdar, S.R. (2007) Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet, 369, 71 77. (Pubitemid 46027230)
    • (2007) Lancet , vol.369 , Issue.9555 , pp. 71-77
    • Padwal, R.S.1    Majumdar, S.R.2
  • 29
    • 0038548401 scopus 로고    scopus 로고
    • Overeating, alcohol and sucrose consumption decrease in CB1 receptor deleted mice
    • DOI 10.1016/S0304-3940(03)00397-5, PII S0304394003003975
    • 1 receptor deleted mice. Neurosci. Lett., 343, 216 218. (Pubitemid 38365988)
    • (2003) Neuroscience Letters , vol.343 , Issue.3 , pp. 216-218
    • Poncelet, M.1    Maruani, J.2    Calassi, R.3    Soubrie, P.4
  • 31
    • 9244224437 scopus 로고    scopus 로고
    • Effect of Fasting on c-Fos Expression in the Hypothalamic Nuclei and Nucleus of the Solitary Tract in Male Rats: Time Course Study and the Role of Testosterone
    • DOI 10.1262/jrd.47.53
    • Reyes, B.A.S., Yamada, S., Estacio, M.A., Maeda, K. Tsukamura, H. (2001) Effect of fasting on c-Fos expression in the hypothalamic nuclei and Nucleus of the solitary tract in male rats: time course study and the role of testosterone. J. Reprod. Dev., 47, 53 62. (Pubitemid 33259097)
    • (2001) Journal of reproduction and development , vol.47 , Issue.1 , pp. 53-62
    • Reyes, B.A.S.1    Yamada, S.2    Estacio, M.A.C.3    Maeda, K.-I.4    Tsukamura, H.5
  • 32
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • DOI 10.1016/0014-5793(94)00773-X
    • Rinaldi-Carmona, M., Barth, F., Héaulme, M., Shire, D., Calandra, B., Congy, C., Martinez, S., Maruani, J., Néliat, G., Caput, D., Ferrara, P., Soubrié, P., Brelière, J.C. Le Fur, G. (1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett., 350, 240 244. (Pubitemid 24268029)
    • (1994) FEBS Letters , vol.350 , Issue.2-3 , pp. 240-244
    • Rinaldi-Carmona, M.1
  • 33
    • 34347336422 scopus 로고    scopus 로고
    • 1 receptor inverse agonists and neutral antagonists: Effects on food intake, food-reinforced behavior and food aversions
    • DOI 10.1016/j.physbeh.2007.04.013, PII S0031938407001357
    • 1 receptor inverse agonists and neutral antagonists: effects on food intake, food-reinforced behavior and food aversions. Physiol. Behav., 24, 383 388. (Pubitemid 47016540)
    • (2007) Physiology and Behavior , vol.91 , Issue.4 , pp. 383-388
    • Salamone, J.D.1    McLaughlin, P.J.2    Sink, K.3    Makriyannis, A.4    Parker, L.A.5
  • 34
    • 0030028250 scopus 로고    scopus 로고
    • 1 cannabinoid receptor antagonist SR
    • 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis.
    • 1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis. Life Sci., 58, PL103 110.
    • (1996) Life Sci. , vol.58 , pp. 103-110
    • Santucci, V.1    Storme, J.J.2    Soubrié, P.3    Le Fur, G.4
  • 36
    • 0026006171 scopus 로고
    • C-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress
    • Sharp, F.R., Sagar, S.M., Hicks, K., Lowenstein, D. Hisanaga, K. (1991) c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress. J. Neurosci., 11, 2321 2331.
    • (1991) J. Neurosci. , vol.11 , pp. 2321-2331
    • Sharp, F.R.1    Sagar, S.M.2    Hicks, K.3    Lowenstein, D.4    Hisanaga, K.5
  • 38
    • 5444268695 scopus 로고    scopus 로고
    • A cannabinoid receptor antagonist attenuates conditioned place preference but not behavioural sensitization to morphine
    • DOI 10.1016/j.brainres.2004.08.027, PII S0006899304013472
    • Singh, M.E., Verty, A.N.A., McGregor, I.S. Mallet, P.E. (2004a) A cannabinoid receptor antagonist attenuates conditioned place preference but not behavioural sensitization to morphine. Brain Res., 1026, 244 253. (Pubitemid 39361553)
    • (2004) Brain Research , vol.1026 , Issue.2 , pp. 244-253
    • Singh, M.E.1    Verty, A.N.A.2    McGregor, I.S.3    Mallet, P.E.4
  • 39
    • 9644275522 scopus 로고    scopus 로고
    • Modulation of morphine-induced Fos-immunoreactivity by the cannabinoid receptor antagonist SR 141716
    • DOI 10.1016/j.neuropharm.2004.08.008, PII S0028390804002552
    • Singh, M.E., Verty, A.N.A., Price, I., McGregor, I.S. Mallet, P.E. (2004b) Modulation of morphine-induced Fos-immunoreactivity by the cannabinoid receptor antagonist SR 141716. Neuropharmacology, 47, 1157 1169. (Pubitemid 39572707)
    • (2004) Neuropharmacology , vol.47 , Issue.8 , pp. 1157-1169
    • Singh, M.E.1    Verty, A.N.A.2    Price, I.3    McGregor, I.S.4    Mallet, P.E.5
  • 40
    • 0042667093 scopus 로고    scopus 로고
    • The cannabinoid receptor antagonist SR 141716 attenuates overfeeding induced by systemic or intracranial morphine
    • DOI 10.1007/s00213-003-1451-9
    • Verty, A.N.A., Singh, M.E., McGregor, I.S. Mallet, P.E. (2003) The cannabinoid receptor antagonist SR 141716 attenuates overfeeding induced by systemic or intracranial morphine. Psychopharmacology, 168, 314 323. (Pubitemid 36920915)
    • (2003) Psychopharmacology , vol.168 , Issue.3 , pp. 314-323
    • Verty, A.N.A.1    Singh, M.E.2    McGregor, I.S.3    Mallet, P.E.4
  • 41
    • 3042640680 scopus 로고    scopus 로고
    • 1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake
    • DOI 10.1210/en.2004-0059
    • 1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake. Endocrinology, 145, 3224 3231. (Pubitemid 38829994)
    • (2004) Endocrinology , vol.145 , Issue.7 , pp. 3224-3231
    • Verty, A.N.A.1    McFarlane, J.R.2    McGregor, I.S.3    Mallet, P.E.4
  • 42
    • 0345791451 scopus 로고    scopus 로고
    • Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats
    • DOI 10.1016/j.neulet.2003.10.035
    • Verty, A.N.A., McGregor, I.S. Mallet, P.E. (2004b) Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats. Neurosci. Lett., 354, 217 220. (Pubitemid 38045348)
    • (2004) Neuroscience Letters , vol.354 , Issue.3 , pp. 217-220
    • Verty, A.N.A.1    McGregor, I.S.2    Mallet, P.E.3
  • 44
    • 58849117501 scopus 로고    scopus 로고
    • The effects of rimonabant on brown adipose tissue in rat: Implications for energy expenditure
    • Verty, A.N.A., Allen, A.M. Oldfield, B.J. (2009) The effects of rimonabant on brown adipose tissue in rat: implications for energy expenditure. Obesity (Silver Spring), 17, 16 24.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 16-24
    • Verty, A.N.A.1    Allen, A.M.2    Oldfield, B.J.3
  • 45
    • 0033561832 scopus 로고    scopus 로고
    • Neurochemical characterization of hypothalamic cocaine- amphetamine-regulated transcript neurons
    • Vrang, N., Larsen, P.J., Clausen, J.T. Kristensen, P. (1999a) Neurochemical characterization of hypothalamic cocaine- amphetamine-regulated transcript neurons. J. Neurosci., 19, RC5 1.
    • (1999) J. Neurosci. , vol.19 , pp. 5-1
    • Vrang, N.1    Larsen, P.J.2    Clausen, J.T.3    Kristensen, P.4
  • 46
    • 0033550726 scopus 로고    scopus 로고
    • Recombinant CART peptide induces c-Fos expression in central areas involved in control of feeding behaviour
    • DOI 10.1016/S0006-8993(98)01349-3, PII S0006899398013493
    • Vrang, N., Tang-Christensen, M., Larsen, P.J. Kristensen, P. (1999b) Recombinant CART peptide induces c-Fos expression in central areas involved in control of feeding behaviour. Brain Res., 818, 499 509. (Pubitemid 29229965)
    • (1999) Brain Research , vol.818 , Issue.2 , pp. 499-509
    • Vrang, N.1    Tang-Christensen, M.2    Larsen, P.J.3    Kristensen, P.4
  • 47
    • 0032936642 scopus 로고    scopus 로고
    • Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
    • DOI 10.1007/s002130050953
    • 1) receptors. Psychopharmacology, 143, 315 317. (Pubitemid 29204987)
    • (1999) Psychopharmacology , vol.143 , Issue.3 , pp. 315-317
    • Williams, C.M.1    Kirkham, T.C.2
  • 48
    • 0036361973 scopus 로고    scopus 로고
    • 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
    • DOI 10.1016/S0091-3057(01)00693-1, PII S0091305701006943
    • 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine. Pharmacol. Biochem. Behav., 71, 341 348. (Pubitemid 34102497)
    • (2002) Pharmacology Biochemistry and Behavior , vol.71 , Issue.1-2 , pp. 341-348
    • Williams, C.M.1    Kirkham, T.C.2
  • 50
    • 0035851851 scopus 로고    scopus 로고
    • The hypothalamus and the control of energy homeostasis: Different circuits, different purposes
    • DOI 10.1016/S0031-9384(01)00612-6, PII S0031938401006126
    • Williams, G., Bing, C., Cai, X.J., Harrold, J.A., King, P.J. Liu, X.H. (2001) The hypothalamus and the control of energy homeostasis: different circuits and different purposes. Physiol. Behav., 74, 683 701. (Pubitemid 34076616)
    • (2001) Physiology and Behavior , vol.74 , Issue.4-5 , pp. 683-701
    • Williams, G.1    Bing, C.2    Cai, X.J.3    Harrold, J.A.4    King, P.J.5    Liu, X.H.6
  • 51
    • 0037177601 scopus 로고    scopus 로고
    • Endocannabinoid signaling in the brain
    • Wilson, R.I. Nicoll, R.A. (2002) Endocannabinoid signaling in the brain. Science, 296, 678 682.
    • (2002) Science , vol.296 , pp. 678-682
    • Wilson, R.I.1    Nicoll, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.