Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450

Journal of Biological Chemistry

Volumn 284, Issue 18, 2009, Pages 11792-11805

  Brodhun, Florian ^a   Göbel, Cornelia ^a   Hornung, Ellen ^a   Feussner, Ivo ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

A-CARBON; ASPERGILLUS NIDULANS; BIFUNCTIONAL; BIOINFORMATIC ANALYSIS; C-TERMINAL REGIONS; CYTOCHROME P450; DIOXYGEN; FILAMENTOUS FUNGI; FUSION PROTEINS; HEME DOMAIN; HEME PEROXIDASE; HEME PROTEINS; LINOLEIC ACID; MODEL ORGANISMS; N-TERMINAL; OXYGENASES; REACTION CATALYZED; REACTION MECHANISM; REACTION STEPS; SEQUENCE ALIGNMENTS; THIOLATE;

ACIDS; CATALYSTS; ENZYMES; ESCHERICHIA COLI; FATTY ACIDS; HEMOGLOBIN;

PORPHYRINS;

CARBON MONOXIDE; CYTOCHROME P450; DIOXYGENASE; FATTY ACID; HEMOPROTEIN; HYBRID PROTEIN; LINOLEIC ACID; PEROXIDASE; POLYUNSATURATED FATTY ACID; PROTEIN PPOA; TETRAMER; UNCLASSIFIED DRUG; FUNGAL PROTEIN; HEME; METALLOPROTEIN; RECOMBINANT PROTEIN; UNSATURATED FATTY ACID;

AMINO TERMINAL SEQUENCE; ARTICLE; ASPERGILLUS NIDULANS; BIOINFORMATICS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ESCHERICHIA COLI; ISOMERIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REACTION ANALYSIS; SEQUENCE ALIGNMENT; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PH; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

EMERICELLA NIDULANS; ESCHERICHIA COLI; FUNGI;

ASPERGILLUS NIDULANS; CYTOCHROME P-450 ENZYME SYSTEM; DIOXYGENASES; ESCHERICHIA COLI; FATTY ACIDS, UNSATURATED; FUNGAL PROTEINS; GENE EXPRESSION; HEME; HYDROGEN-ION CONCENTRATION; METALLOPROTEINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 66449133395     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809152200     Document Type: Article

References (55)

1. Galagan, J. E., Calvo, S. E., Cuomo, C., Ma, L. J., Wortman, J. R., Batzoglou, S., Lee, S. I., Basturkmen, M., Spevak, C. C., Clutterbuck, J., Kapitonov, V., Jurka, J., Scazzocchio, C., Farman, M., Butler, J., Purcell, S., Harris, S., Braus, G. H., Draht, O., Busch, S., D'Enfert, C., Bouchier, C., Goldman, G. H., Bell-Pedersen, D., Griffiths-Jones, S., Doonan, J. H., Yu, J., Vienken, K., Pain, A., Freitag, M., Selker, E. U., Archer, D. B., Penalva, M. A., Oakley, B. R., Momany, M., Tanaka, T., Kumagai, T., Asai, K., Machida, M., Nierman, W. C., Denning, D. W., Caddick, M., Hynes, M., Paoletti, M., Fischer, R., Miller, B., Dyer, P., Sachs, M. S., Osmani, S. A., and Birren, B. W. (2005) Nature 438, 1105-1115
2. Champe, S. P., and el-Zayat, A. A. (1989) J. Bacteriol. 171, 3982-3988
3. Calvo, A. M., Hinze, L. L., Gardner, H. W., and Keller, N. P. (1999) Appl. Environ. Microbiol. 65, 3668-3673
4. Calvo, A. M., Gardner, H. W., and Keller, N. P. (2001) J. Biol. Chem. 276, 25766-25774
5. Calvo, A. M., Wilson, R. A., Bok, J. W., and Keller, N. P. (2002) Microbiol. Mol. Biol. Rev. 66, 447-459
6. Tsitsigiannis, D. I., Kowieski, T. M., Zarnowski, R., and Keller, N. P. (2004) Eukaryot. Cell 3, 1398-1411
7. Tsitsigiannis, D. I., and Keller, N. P. (2006) Mol. Microbiol. 59, 882-892
8. Mazur, P., Meyers, H. V., Nakanishi, K., el-Zayat, A. A. E., and Champe, S. P. (1990) Tetrahedron Lett. 31, 3837-3840
9. Mazur, P., Nakanishi, K., el-Zayat, A. A. E., and Champe, S. P. (1991) J. Chem. Soc. Chem. Commun. 20, 1486-1487
10. Bowers, W. S., Hoch, H. C., Evans, P. H., and Katayama, M. (1986) Science 232, 105-106
11. Brodowsky, I. D., and Oliw, E. H. (1993) Biochim. Biophys. Acta 1168, 68-72
12. Brodowsky, I. D., and Oliw, E. H. (1992) Biochim. Biophys. Acta 1124, 59-65
13. Brodowsky, I. D., Hamberg, M., and Oliw, E. H. (1992) J. Biol. Chem. 267, 14738-14745
14. Su, C., and Oliw, E. H. (1996) J. Biol. Chem. 271, 14112-14118
15. Su, C., Sahlin, M., and Oliw, E. H. (1998) J. Biol. Chem. 273, 20744-20751
16. Tsitsigiannis, D. I., Zarnowski, R., and Keller, N. P. (2004) J. Biol. Chem. 279, 11344-11353
17. Tsitsigiannis, D. I., Kowieski, T. M., Zarnowski, R., and Keller, N. P. (2005) Microbiology (Read.) 151, 1809-1821
18. Smith, W. L., DeWitt, D. L., and Garavito, R. M. (2000) Annu. Rev. Biochem. 69, 145-182
19. Tsitsigiannis, D. I., Bok, J. W., Andes, D., Nielsen, K. F., Frisvad, J. C., and Keller, N. P. (2005) Infect. Immun. 73, 4548-4559
20. Garscha, U., Jerneren, F., Chung, D., Keller, N. P., Hamberg, M., and Oliw, E. H. (2007) J. Biol. Chem. 282, 34707-34718
21. Garscha, U., and Oliw, E. H. (2007) Anal. Biochem. 367, 238-246
22. Hoffmann, M., Hornung, E., Busch, S., Kassner, N., Ternes, P., Braus, G. H., and Feussner, I. (2007) J. Biol. Chem. 282, 26666-26674
23. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 61-68
24. Antonini, E., and Brunori, M. (1971) Hemoglobin and Myoglobin and Their Reaction with Ligands, North Holland Publishing Co., Amsterdam
25. Omura, T., and Sato, R. (1964) J. Biol. Chem. 239, 2379-2385
26. Kulmacz, R. J. (1987) Prostaglandins 34, 225-240
27. Omura, T., and Sato, R. (1964) J. Biol. Chem. 239, 2370-2378
28. Sasaki, M., Akahira, A., Oshiman, K., Tsuchido, T., and Matsumura, Y. (2005) Appl. Environ. Microbiol. 71, 8024-8030
29. Yeh, H. C., Hsu, P. Y., Wang, J. S., Tsai, A. L., and Wang, L. H. (2005) Biochim. Biophys. Acta 1738, 121-132
30. Lau, S.-M. C., Harder, P. A., and O'Keefe, D. P. (1993) Biochemistry 32, 1945-1950
31. Landino, L. M., Crews, B. C., Gierse, J. K., Hauser, S. D., and Marnett, L. J. (1997) J. Biol. Chem. 272, 21565-21574
32. Kulmacz, R. J., Pendleton, R. B., and Lands, W. E. (1994) J. Biol. Chem. 269, 5527-5536
33. Koshiishi, I., Tsuchida, K., Takajo, T., and Komatsu, M. (2006) Biochem. J. 395, 303-309
34. Takajo, T., Tsuchida, K., Ueno, K., and Koshiishi, I. (2007) J. Lipid Res. 48, 1371-1377
35. Takajo, T., Tsuchida, K., Murahashi, T., Ueno, K., and Koshiishi, I. (2007) J. Lipid Res. 48, 855-862
36. Koshiishi, I., Tsuchida, K., Takajo, T., and Komatsu, M. (2005) J. Lipid Res. 46, 2506-2513
37. Liavonchanka, A., and Feussner, I. (2006) J. Plant Physiol. 163, 348-357
38. Shimokawa, T., Kulmacz, R. J., DeWitt, D. L., and Smith, W. L. (1990) J. Biol. Chem. 265, 20073-20076
39. Garscha, U., and Oliw, E. H. (2008) FEBS Lett. 582, 3547-3551
40. Koeduka, T., Matsui, K., Akakabe, Y., and Kajiwara, T. (2002) J. Biol. Chem. 277, 22648-22655
41. Yano, J. K., Koo, L. S., Schuller, D. J., Li, H., Ortiz de Montellano, P. R., and Poulos, T. L. (2000) J. Biol. Chem. 275, 31086-31092
42. Thuresson, E. D., Lakkides, K. M., Rieke, C. J., Sun, Y., Wingerd, B. A., Micielli, R., Mulichak, A. M., Malkowski, M. G., Garavito, R. M., and Smith, W. L. (2001) J. Biol. Chem. 276, 10347-10357
43. Tsitsigiannis, D. I., and Keller, N. P. (2007) Trends Microbiol. 15, 109-118
44. Song, W.-C., and Brash, A. R. (1991) Science 253, 781-784
45. Sanz, A., Moreno, J. I., and Castresana, C. (1998) Plant Cell 10, 1523-1537
46. Ohki, S., Ogino, N., Yamamoto, S., and Hayaishi, O. (1979) J. Biol. Chem. 254, 829-836
47. Hamberg, M., Zhang, L. Y., Brodowsky, I. D., and Oliw, E. H. (1994) Arch. Biochem. Biophys. 309, 77-80
48. Garscha, U., and Oliw, E. H. (2008) Biochem. Biophys. Res. Commun. 373, 579-583
49. Coon, M. J. (2005) Annu. Rev. Pharmacol. Toxicol. 45, 1-25
50. Lee, D.-S., Nioche, P., Hamberg, M., and Raman, C. S. (2008) Nature 455, 363-368
51. Chiang, C. W., Yeh, H. C., Wang, L. H., and Chan, N. L. (2006) J. Mol. Biol. 364, 266-274
52. Lu, G. Q., Tsai, A. L., Van Wart, H. E., and Kulmacz, R. J. (1999) J. Biol. Chem. 274, 16162-16167
53. Kupfer, R., Liu, S. Y., Allentoff, A. J., and Thompson, J. A. (2001) Biochemistry 40, 11490-11501
54. Picot, D., Loll, P. J., and Garavito, R. M. (1994) Nature 367, 243-249
55. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254