Staphylococcus aureus α-toxin and Escherichia coli hemolysin impair cardiac regional perfusion and contractile function by activating myocardial eicosanoid metabolism in isolated rat hearts

Critical Care Medicine

Volumn 37, Issue 6, 2009, Pages 2025-2032

  Grandel, Ulrich ^a   Bennemann, Ulrich ^a   Buerke, Michael ^b   Hattar, Katja ^a   Seeger, Werner ^a   Grimminger, Friedrich ^a   Sibelius, Ulf ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Bacterial exotoxins; Cardiac regional perfusion; Heart failure; Leukotrienes; Sepsis; Thromboxane

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ALPHA TOXIN; HEMOLYSIN; ICOSANOID; INDOMETACIN; MICROSPHERE; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2; BACTERIAL TOXIN; ESCHERICHIA COLI PROTEIN; HLYA PROTEIN, E COLI; STAPHYLOCOCCAL ALPHA-TOXIN; STAPHYLOCOCCUS ALPHA TOXIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY VASCULAR RESISTANCE; ESCHERICHIA COLI; HEART DISEASE; HEART PERFUSION; ICOSANOID METABOLISM; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; STAPHYLOCOCCUS AUREUS; ANIMAL; DRUG EFFECT; HEART CONTRACTION; HEART MUSCLE; IN VITRO STUDY; METABOLISM; WISTAR RAT;

ANIMALS; BACTERIAL TOXINS; CORONARY CIRCULATION; EICOSANOIDS; ESCHERICHIA COLI PROTEINS; HEMOLYSIN PROTEINS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; RATS; RATS, WISTAR;

EID: 66449110073     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819fff00     Document Type: Article

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