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Volumn 21, Issue 2, 2009, Pages 123-128

Analysis of Resistance to Clarithromycin and Virulence Markers in Helicobacter pylori Clinical Isolates from Eastern Taiwan

Author keywords

Clarithromycin resistant; Genotyping; Helicobacter pylori; Virulence marker

Indexed keywords

ADENINE; CAGA PROTEIN; CLARITHROMYCIN; CYTOSINE; DNA 23S; GUANINE; ICEA PROTEIN; THREONINE; UNCLASSIFIED DRUG; VACUOLATING TOXIN; VIRULENCE FACTOR;

EID: 66449106611     PISSN: 10163190     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1016-3190(09)60023-9     Document Type: Article
Times cited : (2)

References (44)
  • 2
    • 0001073992 scopus 로고
    • Epidemiology and natural history of H. pylori infections
    • Blaser M.J., Smith P.F., Ravdin J., Greenberg H., and Guerrant R.L. (Eds), Raven, New York
    • Taylor D.N., and Parsonnet J. Epidemiology and natural history of H. pylori infections. In: Blaser M.J., Smith P.F., Ravdin J., Greenberg H., and Guerrant R.L. (Eds). Infections of the Gastrointestinal Tract (1995), Raven, New York 551-564
    • (1995) Infections of the Gastrointestinal Tract , pp. 551-564
    • Taylor, D.N.1    Parsonnet, J.2
  • 3
    • 0027070575 scopus 로고
    • Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study
    • Graham D.Y., Lew G.M., Klein P.D., et al. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med 116 (1992) 705-708
    • (1992) Ann Intern Med , vol.116 , pp. 705-708
    • Graham, D.Y.1    Lew, G.M.2    Klein, P.D.3
  • 4
    • 0028230879 scopus 로고
    • Helicobacter pylori infection and gastric lymphoma
    • Parsonnet J., Hansen S., Rodriguez L., et al. Helicobacter pylori infection and gastric lymphoma. N Engl J Med 330 (1994) 1267-1271
    • (1994) N Engl J Med , vol.330 , pp. 1267-1271
    • Parsonnet, J.1    Hansen, S.2    Rodriguez, L.3
  • 5
    • 0027972480 scopus 로고
    • H pylori and gastric cancer
    • Forman D., Webb P., and Parsonnet J. H pylori and gastric cancer. Lancet 343 (1994) 243-244
    • (1994) Lancet , vol.343 , pp. 243-244
    • Forman, D.1    Webb, P.2    Parsonnet, J.3
  • 6
    • 0027930991 scopus 로고
    • Gastric adenocarcinoma and Helicobacter pylori infection
    • Parsonnet J. Gastric adenocarcinoma and Helicobacter pylori infection. West J Med 161 (1994) 60
    • (1994) West J Med , vol.161 , pp. 60
    • Parsonnet, J.1
  • 7
    • 0026075078 scopus 로고
    • Helicobacter pylori and chronic gastritis: an increased risk of peptic ulcer? A review
    • Sipponen P. Helicobacter pylori and chronic gastritis: an increased risk of peptic ulcer? A review. Scand J Gastroenterol Suppl 186 (1991) 6-10
    • (1991) Scand J Gastroenterol Suppl , vol.186 , pp. 6-10
    • Sipponen, P.1
  • 8
    • 34247231984 scopus 로고    scopus 로고
    • Resistance rate to antibiotics of Helicobacter pylori isolates in eastern Taiwan
    • Hu C.T., Wu C.C., Lin C.Y., et al. Resistance rate to antibiotics of Helicobacter pylori isolates in eastern Taiwan. J Gastroenterol Hepatol 22 (2007) 720-723
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 720-723
    • Hu, C.T.1    Wu, C.C.2    Lin, C.Y.3
  • 9
    • 0030068225 scopus 로고    scopus 로고
    • Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori
    • Versalovic J., Shortridge D., Kibler K., et al. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob Agents Chemother 40 (1996) 477-480
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 477-480
    • Versalovic, J.1    Shortridge, D.2    Kibler, K.3
  • 10
    • 0030734728 scopus 로고    scopus 로고
    • Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations
    • Taylor D.E., Ge Z., Purych D., Lo T., and Hiratsuka K. Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations. Antimicrob Agents Chemother 41 (1997) 2621-2628
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2621-2628
    • Taylor, D.E.1    Ge, Z.2    Purych, D.3    Lo, T.4    Hiratsuka, K.5
  • 11
    • 0030834006 scopus 로고    scopus 로고
    • Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes
    • Occhialini A., Urdaci M., Doucet-Populaire F., Bebear C.M., Lamouliatte H., and Megraud F. Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes. Antimicrob Agents Chemother 41 (1997) 2724-2728
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2724-2728
    • Occhialini, A.1    Urdaci, M.2    Doucet-Populaire, F.3    Bebear, C.M.4    Lamouliatte, H.5    Megraud, F.6
  • 12
    • 0030309699 scopus 로고    scopus 로고
    • Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori
    • Stone G.G., Shortridge D., Flamm R.K., et al. Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori. Helicobacter 1 (1996) 227-228
    • (1996) Helicobacter , vol.1 , pp. 227-228
    • Stone, G.G.1    Shortridge, D.2    Flamm, R.K.3
  • 13
    • 0030725251 scopus 로고    scopus 로고
    • Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients
    • Hulten K., Gibreel A., Skold O., and Engstrand L. Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients. Antimicrob Agents Chemother 41 (1997) 2550-2553
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2550-2553
    • Hulten, K.1    Gibreel, A.2    Skold, O.3    Engstrand, L.4
  • 14
    • 1842858319 scopus 로고    scopus 로고
    • Mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance
    • Kim K.S., Kang J.O., Eun C.S., Han D.S., and Choi T.Y. Mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance. J Korean Med Sci 17 (2002) 599-603
    • (2002) J Korean Med Sci , vol.17 , pp. 599-603
    • Kim, K.S.1    Kang, J.O.2    Eun, C.S.3    Han, D.S.4    Choi, T.Y.5
  • 15
    • 4644310433 scopus 로고    scopus 로고
    • Identification of a novel mutation affecting domain V of the 23S rRNA gene in Helicobacter pylori
    • Toracchio S., Aceto G.M., Mariani-Costantini R., Battista P., and Marzio L. Identification of a novel mutation affecting domain V of the 23S rRNA gene in Helicobacter pylori. Helicobacter 9 (2004) 396-399
    • (2004) Helicobacter , vol.9 , pp. 396-399
    • Toracchio, S.1    Aceto, G.M.2    Mariani-Costantini, R.3    Battista, P.4    Marzio, L.5
  • 16
    • 0031750247 scopus 로고    scopus 로고
    • Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori
    • van Doorn L.J., Figueiredo C., Sanna R., et al. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 115 (1998) 58-66
    • (1998) Gastroenterology , vol.115 , pp. 58-66
    • van Doorn, L.J.1    Figueiredo, C.2    Sanna, R.3
  • 17
    • 20444448879 scopus 로고    scopus 로고
    • Clinical relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan
    • Wu C.C., Chou P.Y., Hu C.T., et al. Clinical relevance of the vacA, iceA, cagA, and flaA genes of Helicobacter pylori strains isolated in Eastern Taiwan. J Clin Microbiol 43 (2005) 2913-2915
    • (2005) J Clin Microbiol , vol.43 , pp. 2913-2915
    • Wu, C.C.1    Chou, P.Y.2    Hu, C.T.3
  • 18
    • 0027173990 scopus 로고
    • Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
    • Covacci A., Censini S., Bugnoli M., et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 90 (1993) 5791-5795
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5791-5795
    • Covacci, A.1    Censini, S.2    Bugnoli, M.3
  • 19
    • 0031032033 scopus 로고    scopus 로고
    • Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori
    • Atherton J.C., Peek Jr. R.M., Tham K.T., Cover T.L., and Blaser M.J. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 112 (1997) 92-99
    • (1997) Gastroenterology , vol.112 , pp. 92-99
    • Atherton, J.C.1    Peek Jr., R.M.2    Tham, K.T.3    Cover, T.L.4    Blaser, M.J.5
  • 20
    • 4444348018 scopus 로고    scopus 로고
    • Helicobacter pylori antibiotic resistance patterns and genotypes in adult dyspeptic patients from a regional population in North Wales
    • Elviss N.C., Owen R.J., Xerry J., Walker A.M., and Davies K. Helicobacter pylori antibiotic resistance patterns and genotypes in adult dyspeptic patients from a regional population in North Wales. J Antimicrob Chemother 54 (2004) 435-440
    • (2004) J Antimicrob Chemother , vol.54 , pp. 435-440
    • Elviss, N.C.1    Owen, R.J.2    Xerry, J.3    Walker, A.M.4    Davies, K.5
  • 21
    • 3042701778 scopus 로고    scopus 로고
    • Genetic and phenotype changes following in vitro interactions between Helicobacter pylori strains
    • Yakoob J., Fan X., Hu G., and Zhang Z. Genetic and phenotype changes following in vitro interactions between Helicobacter pylori strains. J Gastroenterol Hepatol 19 (2004) 626-631
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 626-631
    • Yakoob, J.1    Fan, X.2    Hu, G.3    Zhang, Z.4
  • 22
    • 33750297050 scopus 로고    scopus 로고
    • Analysis of resistance to clarithromycin and iceA status in Helicobacter pylori isolates from San Luis, Argentina
    • Stege P.W., and Vega A.E. Analysis of resistance to clarithromycin and iceA status in Helicobacter pylori isolates from San Luis, Argentina. Int J Antimicrob Agents 28 (2006) 477-478
    • (2006) Int J Antimicrob Agents , vol.28 , pp. 477-478
    • Stege, P.W.1    Vega, A.E.2
  • 23
    • 33644583461 scopus 로고    scopus 로고
    • Analysis of genetic variability, antimicrobial susceptibility and virulence markers in Helicobacter pylori identified in Central Italy
    • Cellini L., Grande R., Di Campli E., Di Bartolomeo S., Capodicasa S., and Marzio L. Analysis of genetic variability, antimicrobial susceptibility and virulence markers in Helicobacter pylori identified in Central Italy. Scand J Gastroenterol 41 (2006) 280-287
    • (2006) Scand J Gastroenterol , vol.41 , pp. 280-287
    • Cellini, L.1    Grande, R.2    Di Campli, E.3    Di Bartolomeo, S.4    Capodicasa, S.5    Marzio, L.6
  • 24
    • 0027068228 scopus 로고
    • PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori
    • Akopyanz N., Bukanov N.O., Westblom T.U., and Berg D.E. PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori. Nucleic Acids Res 20 (1992) 6221-6225
    • (1992) Nucleic Acids Res , vol.20 , pp. 6221-6225
    • Akopyanz, N.1    Bukanov, N.O.2    Westblom, T.U.3    Berg, D.E.4
  • 25
    • 0035075021 scopus 로고    scopus 로고
    • Molecular resistance testing of Helicobacter pylori in gastric biopsies
    • Pena J.A., Fox J.G., Ferraro M.J., and Versalovic J. Molecular resistance testing of Helicobacter pylori in gastric biopsies. Arch Pathol Lab Med 125 (2001) 493-497
    • (2001) Arch Pathol Lab Med , vol.125 , pp. 493-497
    • Pena, J.A.1    Fox, J.G.2    Ferraro, M.J.3    Versalovic, J.4
  • 26
    • 4344592305 scopus 로고    scopus 로고
    • H pylori antibiotic resistance: prevalence, importance, and advances in testing
    • Megraud F. H pylori antibiotic resistance: prevalence, importance, and advances in testing. Gut 53 (2004) 1374-1384
    • (2004) Gut , vol.53 , pp. 1374-1384
    • Megraud, F.1
  • 27
    • 0034500324 scopus 로고    scopus 로고
    • Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada
    • Fallone C.A. Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. Can J Gastroenterol 14 (2000) 879-882
    • (2000) Can J Gastroenterol , vol.14 , pp. 879-882
    • Fallone, C.A.1
  • 28
    • 0034925027 scopus 로고    scopus 로고
    • Pattern of primary resistance of Helicobacter pylori to metronidazole or clarithromycin in the United States
    • Osato M.S., Reddy R., Reddy S.G., Penland R.L., Malaty H.M., and Graham D.Y. Pattern of primary resistance of Helicobacter pylori to metronidazole or clarithromycin in the United States. Arch Intern Med 161 (2001) 1217-1220
    • (2001) Arch Intern Med , vol.161 , pp. 1217-1220
    • Osato, M.S.1    Reddy, R.2    Reddy, S.G.3    Penland, R.L.4    Malaty, H.M.5    Graham, D.Y.6
  • 29
    • 0344643017 scopus 로고    scopus 로고
    • Clarithromycin resistance in Iranian H. pylori strains before introduction of clarithromycin
    • Mohammadi M., Doroud D., Massarrat S., and Farahvash M.J. Clarithromycin resistance in Iranian H. pylori strains before introduction of clarithromycin. Helicobacter 8 (2003) 80
    • (2003) Helicobacter , vol.8 , pp. 80
    • Mohammadi, M.1    Doroud, D.2    Massarrat, S.3    Farahvash, M.J.4
  • 30
    • 0035992148 scopus 로고    scopus 로고
    • Resistance of Helicobacter pylori isolated in Israel to metronidazole, clarithromycin, tetracycline, amoxicillin and cefixime
    • Samra Z., Shmuely H., Niv Y., et al. Resistance of Helicobacter pylori isolated in Israel to metronidazole, clarithromycin, tetracycline, amoxicillin and cefixime. J Antimicrob Chemother 49 (2002) 1023-1026
    • (2002) J Antimicrob Chemother , vol.49 , pp. 1023-1026
    • Samra, Z.1    Shmuely, H.2    Niv, Y.3
  • 31
    • 0033929895 scopus 로고    scopus 로고
    • Regional differences in metronidazole resistance and increasing clarithromycin resistance among Helicobacter pylori isolates from Japan
    • Kato M., Yamaoka Y., Kim J.J., et al. Regional differences in metronidazole resistance and increasing clarithromycin resistance among Helicobacter pylori isolates from Japan. Antimicrob Agents Chemother 44 (2000) 2214-2216
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2214-2216
    • Kato, M.1    Yamaoka, Y.2    Kim, J.J.3
  • 32
    • 0034946064 scopus 로고    scopus 로고
    • Prevalence and rapid identification of clarithromycin-resistant Helicobacter pylori isolates in children
    • Yang Y.J., Yang J.C., Jeng Y.M., Chang M.H., and Ni Y.H. Prevalence and rapid identification of clarithromycin-resistant Helicobacter pylori isolates in children. Pediatr Infect Dis J 20 (2001) 662-666
    • (2001) Pediatr Infect Dis J , vol.20 , pp. 662-666
    • Yang, Y.J.1    Yang, J.C.2    Jeng, Y.M.3    Chang, M.H.4    Ni, Y.H.5
  • 33
    • 0033822871 scopus 로고    scopus 로고
    • Impact of Helicobacter pylori antimicrobial resistance on the outcome of 1-week lansoprazole-based triple therapy
    • Huang A.H., Sheu B.S., Yang H.B., Huang C.C., Wu J.J., and Lin X.Z. Impact of Helicobacter pylori antimicrobial resistance on the outcome of 1-week lansoprazole-based triple therapy. J Formos Med Assoc 99 (2000) 704-709
    • (2000) J Formos Med Assoc , vol.99 , pp. 704-709
    • Huang, A.H.1    Sheu, B.S.2    Yang, H.B.3    Huang, C.C.4    Wu, J.J.5    Lin, X.Z.6
  • 34
    • 0036400145 scopus 로고    scopus 로고
    • The antimicrobial susceptibility of Helicobacter pylori in Hong Kong (1997-2001)
    • Ling T.K., Leung W.K., Lee C.C., et al. The antimicrobial susceptibility of Helicobacter pylori in Hong Kong (1997-2001). Helicobacter 7 (2002) 327-328
    • (2002) Helicobacter , vol.7 , pp. 327-328
    • Ling, T.K.1    Leung, W.K.2    Lee, C.C.3
  • 35
    • 0035048039 scopus 로고    scopus 로고
    • Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea
    • Kim J.J., Reddy R., Lee M., et al. Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea. J Antimicrob Chemother 47 (2001) 459-461
    • (2001) J Antimicrob Chemother , vol.47 , pp. 459-461
    • Kim, J.J.1    Reddy, R.2    Lee, M.3
  • 36
    • 0032772954 scopus 로고    scopus 로고
    • Rapid detection, by PCR and reverse hybridization, of mutations in the Helicobacter pylori 23S rRNA gene, associated with macrolide resistance
    • van Doorn L.J., Debets-Ossenkopp Y.J., Marais A., et al. Rapid detection, by PCR and reverse hybridization, of mutations in the Helicobacter pylori 23S rRNA gene, associated with macrolide resistance. Antimicrob Agents Chemother 43 (1999) 1779-1782
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1779-1782
    • van Doorn, L.J.1    Debets-Ossenkopp, Y.J.2    Marais, A.3
  • 37
    • 1842666771 scopus 로고    scopus 로고
    • New mutation points in 23S rRNA gene associated with Helicobacter pylori resistance to clarithromycin in northeast China
    • Hao Q., Li Y., Zhang Z.J., Liu Y., and Gao H. New mutation points in 23S rRNA gene associated with Helicobacter pylori resistance to clarithromycin in northeast China. World J Gastroenterol 10 (2004) 1075-1077
    • (2004) World J Gastroenterol , vol.10 , pp. 1075-1077
    • Hao, Q.1    Li, Y.2    Zhang, Z.J.3    Liu, Y.4    Gao, H.5
  • 38
    • 0030770494 scopus 로고    scopus 로고
    • Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance
    • Versalovic J., Osato M.S., Spakovsky K., et al. Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. J Antimicrob Chemother 40 (1997) 283-286
    • (1997) J Antimicrob Chemother , vol.40 , pp. 283-286
    • Versalovic, J.1    Osato, M.S.2    Spakovsky, K.3
  • 39
    • 0031038201 scopus 로고    scopus 로고
    • A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori
    • Stone G.G., Shortridge D., Versalovic J., et al. A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori. Antimicrob Agents Chemother 41 (1997) 712-714
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 712-714
    • Stone, G.G.1    Shortridge, D.2    Versalovic, J.3
  • 40
    • 0033789006 scopus 로고    scopus 로고
    • Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA
    • Alarcon T., Domingo D., Prieto N., and Lopez-Brea M. Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA. J Antimicrob Chemother 46 (2000) 613-616
    • (2000) J Antimicrob Chemother , vol.46 , pp. 613-616
    • Alarcon, T.1    Domingo, D.2    Prieto, N.3    Lopez-Brea, M.4
  • 41
    • 0035040822 scopus 로고    scopus 로고
    • Accurate prediction of macrolide resistance in Helicobacter pylori by a PCR line probe assay for detection of mutations in the 23S rRNA gene: multicenter validation study
    • van Doorn L.J., Glupczynski Y., Kusters J.G., et al. Accurate prediction of macrolide resistance in Helicobacter pylori by a PCR line probe assay for detection of mutations in the 23S rRNA gene: multicenter validation study. Antimicrob Agents Chemother 45 (2001) 1500-1504
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1500-1504
    • van Doorn, L.J.1    Glupczynski, Y.2    Kusters, J.G.3
  • 42
    • 0036162237 scopus 로고    scopus 로고
    • Antibiotic resistance of Helicobacter pylori strains in Japanese children
    • Kato S., Fujimura S., Udagawa H., et al. Antibiotic resistance of Helicobacter pylori strains in Japanese children. J Clin Microbiol 40 (2002) 649-653
    • (2002) J Clin Microbiol , vol.40 , pp. 649-653
    • Kato, S.1    Fujimura, S.2    Udagawa, H.3
  • 43
    • 0036136494 scopus 로고    scopus 로고
    • Assessment of clarithromycin-resistant Helicobacter pylori among patients in Shanghai and Guangzhou, China, by primer-mismatch PCR
    • Pan Z.J., Su W.W., Tytgat G.N., Dankert J., and van der Ende A. Assessment of clarithromycin-resistant Helicobacter pylori among patients in Shanghai and Guangzhou, China, by primer-mismatch PCR. J Clin Microbiol 40 (2002) 259-261
    • (2002) J Clin Microbiol , vol.40 , pp. 259-261
    • Pan, Z.J.1    Su, W.W.2    Tytgat, G.N.3    Dankert, J.4    van der Ende, A.5
  • 44
    • 0035160878 scopus 로고    scopus 로고
    • Macrolide resistance conferred by base substitutions in 23S rRNA
    • Vester B., and Douthwaite S. Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother 45 (2001) 1-12
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1-12
    • Vester, B.1    Douthwaite, S.2


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