Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori

Helicobacter

Volumn 1, Issue 4, 1996, Pages 227-228

  Stone, Gregory G ^a   Shortridge, Dee ^a   Flamm, Robert K ^a   Versalovic, James ^b   Beyer, Jill ^a   Idler, Ken ^a   Zulawinski, Laura ^a   Tanaka, S Ken ^a  

^a ABBOTT LABORATORIES   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL RNA; CLARITHROMYCIN; RIBOSOME DNA; RNA 23S;

ANTIBIOTIC RESISTANCE; ARTICLE; DRUG EFFECT; GENETICS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION;

CLARITHROMYCIN; DNA, BACTERIAL; DNA, RIBOSOMAL; DRUG RESISTANCE, MICROBIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; POINT MUTATION; POLYMERASE CHAIN REACTION; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S;

EID: 0030309699     PISSN: 10834389     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-5378.1996.tb00043.x     Document Type: Article

References (9)

1. Graham DY, Lew GM, Klein PD, Evans DG, Evans DJ Jr., Saeed ZA, Malaty HM. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med 1992; 116:705-8.
2. Sung JJ, Chung SC, Ling TK, Yung MY, Leung VK, Ng EK, Li MK, Cheng AF, Li AK. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Engl J Med 1995;332:139-42.
3. Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Edit S, Stolte M, Group MLS. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet 1995;345:1591-4.
4. Versalovic J, Shortridge D, Kibler K, Griffy MV, Beyer J, Flamm RK, Tanaka SK, Graham DY, Go MG. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob Agents Chemother 1996;40:477-80.
5. Hardy DJ, Hanson CW, Hensey DM, Beyer JM, Fernandes PB. Susceptibility of Campylobacter pylori to macrolides and fluoroquinolones. J Antimicrob Chemother 1988;22:631-6.
6. Program manual for the Genetics Computer Group package, version 7.575. Genetics Computer Group, Madison, WI.
7. Meier A, Kirschner P, Springer B, Steingrube VA, Brown BA, Wallace RJ, Bottger EC. Identification of mutations in 23S rRNA gene of clarithromycinresistant Mycobacterium intracellulare. Antimicrob Agents Chemother 1994;38:381-4
8. Nash K, Inderlied CB. Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. Antimicrob Agents Chemother 1995;39:2625-30.
9. Pernodet J-L, Boccard F, Alegre M-T, Blondelet-Rovault M-H, Guerineau M. Resistance to macrolides, lincosamides, and streptogramin type B antibiotics due to mutation in an rRNA operon of Streptomyces ambofaciens. EMBO J 1988;7:277-82.