Rapid detection, by PCR and reverse hybridization, of mutations in the Helicobacter pylori 23S rRNA gene, associated with macrolide resistance

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 7, 1999, Pages 1779-1782

  Van Doorn, Leen Jan ^a   Debets Ossenkopp, Yvette J ^b   Marais, Armelle ^c   Sanna, Ricardo ^a   Mégraud, Francis ^c   Kusters, Johannes G ^b   Quint, Wim G V ^a  

^a Delft Diagnostic Laboratory   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c HÔPITAL PELLEGRIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; CLARITHROMYCIN; MACROLIDE; RNA 23S;

ACCURACY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA DETERMINATION; GENETIC RESISTANCE; HELICOBACTER PYLORI; INTERMETHOD COMPARISON; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRAIN DIFFERENCE;

EID: 0032772954     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.7.1779     Document Type: Article

References (22)

1. Blaser, M. J. 1997. Ecology of Helicobacler pylori in the human stomach. J. Clin. Investig. 100:759-762.
2. Broutet, N., F. Guillon, E. Sauty, D. Lethuaire, and F. Mégraud. 1998. Survey of the in vitro susceptibility of Helicobacter pylori to antibiotics in France - preliminary results. Gut 43:A11.
3. Debets-Ossenkopp, Y. J., A. B. Brinkman, E. J. Kuipers, C. M. J. E. Vandenbroucke-Grauls, and J. G. Kusters. 1998. Explaining the bias in the 23S rRNA gene mutations associated with clarithromycin resistance in clinical isolates of Helicobacter pylori. Antimicrob. Agents Chemother. 42:2749-2751.
4. Debets-Ossenkopp, Y. J., M. Sparrius, J. G. Kusters, J. J. Kolkman, and C. M. Vandenbroucke-Grauls. 1996. Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. FEMS Microbiol. Lett. 142:37-42.
5. de Boer, W. A., and G. N. J. Tytgat. 1995. The best therapy of Helicobacter pylori infection. Scand. J. Gastroenterol. 30:401-407.
6. Dore, M. P., B. Are, M. Carta, I. Mura, A. Maida, and G. Realdi. 1998. Antibiotic resistant H. pylori are extremely common in Sardinia. Gastroenterology 114:G0445. (Abstract.)
7. Dunn, B. E., H. Cohen, and M. J. Blaser. 1997. Helicobacter pylori. Clin. Microbiol. Rev. 10:720-741.
8. Glupczynski, Y., S. Goutier, C. Van de Borre, J. P. Butzler, and A. Burette. 1995. Surveillance of Helicobacter pylori resistance to antimicrobial agents in Belgium from 1989 to 1994. Gut 37:A56. (Abstract.)
9. Glupczynski, Y., M. Labbé, W. Hansen, F. Crokaert, and E. Yourassowsky. 1991. Evaluation of the E test for quantitative antimicrobial susceptibility testing of Helicobacter pylori. J. Clin. Microbiol. 29:2072-2075.
10. Hultén, K., A. Gibreel, O. Sköld, and L. Engstrand. 1997. Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients. Antimicrob. Agents Chemother. 41:2550-2553.
11. Lopez-Brea, M., M. J. Martinez, and D. Domingo. 1995. Evolution of the resistance to several antibiotics in H. pylori over a 4-year period. Gut 37:A56. (Abstract.)
12. Mégraud, F. 1997. Resistance of Helicobacter pylori to antibiotics. Aliment. Pharmacol. Ther. 11(Suppl. 1):43-53.
13. Midolo, P. D., J. M. Bell, J. R. Lambert, J. D. Turnidge, and M. L. Grayson. 1997. Antimicrobial resistance testing of Helicobacter pylori: a comparison of E-test and disk diffusion methods. Pathology 29:411-414.
14. Morton, D., and K. D. Bardhan. 1998. A six-year assessment of tinidazole, metronidazole, clarithromycin, tetracycline and amoxicillin resistance in Helicobacter pylori clinical isolates: a rising tide of antibiotic resistance? Gastroenterology 114:3620. (Abstract.)
15. Occhialini, A., M. Urdaci, F. Doucet-Populaire, C. M. Bébear, H. Lamouliatte, and F. Mégraud. 1997. Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes. Antimicrob. Agents Chemother. 41:2724-2728.
16. Pina, M., A. Occhialini, L. Monteiro, H. P. Doermann, and F. Mégraud. 1998. Detection of point mutations associated with resistance of Helicobacter pylori to clarithromycin by hybridization in liquid phase. J. Clin. Microbiol. 36:3285-3290.
17. Takahashi, S., T. Itoh, H. Ninomiya, S. Hoshiya, K. Watanabe, K. Tokunaga, A. Tanaka, N. Nakamura, N. Masubuchi, M. Shingaki, and S. Saito. 1998. Evolution of Helicobacter pylori antibiotic resistance in Japan (1985-1997). Gastroenterology 114:01240. (Abstract.)
18. van der Hulst, R. W., J. J. Keller, E. A. Rauws, and G. M. Tytgat. 1996. Treatment of Helicobacter pylori: review of the world literature. Helicobacter 1:6-19.
19. 18a. van Doom, L.-J., C. Figueiredo, R. Sanna, S. Pena, P. Midolo, E. K. W. Ng, J. C. Atherton, M. J. Blaser, and W. G. V. Quint. 1998. Expanding allelic diversity of Helicobacter pylori vacA. J. Clin. Microbiol. 36:2597-2603.
20. van Zwet, A. A., W. A. de Boer, P. Schneeberger, J. F. Weel, A. R. Jansz, and J. C. Thijs. 1996. Prevalence of primary Helicobacter pylori resistance to metronidazole and clarithromycin in the Netherlands. Eur. J. Clin. Microbiol. Infect. Dis. 15:861-864.
21. Versalovic, J., D. Shortridge, K. Kibler, M. V. Griffy, J. Beyer, R. K. Flamm, S. K. Tanaka, D. Y. Graham, and M. F. Go. 1996. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 40:477-480.
22. Weisblum, B. 1995. Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. 39:577-585.