N-Substituted-2-alkyl- and 2-arylnorapomorphines: Novel, highly active D2 agonists

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4756-4762

  Herm, Laura ^a   Berényi, Sándor ^b   Vonk, Argo ^a   Rinken, Ago ^a   Sipos, Attila ^b  

^a UNIVERSITY OF TARTU   (Estonia)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Apomorphine derivatives; Dopamine receptor activity; N Oxidation; N Substitution; Suzuki Miyaura reaction

Indexed keywords

2 (4 HYDROXYPHENYL)NORAPOMORPHINE DERIVATIVE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; APOMORPHINE; APORPHINE DERIVATIVE; APORPHINOID; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; MORPHINAN DERIVATIVE; N ETHYL 2 (4 HYDROXYPHENYL)NORAPOMORPHINE; N PROPYL 2 (4 HYDROXYPHENYL)NORAPOMORPHINE; NORAPOMORPHINE DERIVATIVE; RACLOPRIDE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATALYSIS; CHO CELL; DRUG SYNTHESIS; NONHUMAN; PRODUCT RECOVERY; REACTION ANALYSIS; SUBSTITUTION REACTION;

ANIMALS; APOMORPHINE; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; FIBROBLASTS; PROTEIN BINDING; RATS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 66449100027     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.04.047     Document Type: Article

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