Effect of denervation of the locus coeruleus projections by DSP-4 treatment on [3H]-raclopride binding to dopamine D2 receptors and D2 receptor-G protein interaction in the rat striatum

Brain Research

Volumn 976, Issue 2, 2003, Pages 209-216

  Harro, Jaanus ^a   Terasmaa, Anton ^a   Eller, Marika ^a   Rinken, Ago ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

D2 receptor; Dopamine; DSP 4; G protein; Locus coeruleus; Striatum

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); RACLOPRIDE; SEROTONIN;

ARTICLE; AUTONOMIC DENERVATION; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CORPUS STRIATUM; DECAPITATION; DOPAMINERGIC SYSTEM; DRUG BINDING; DRUG EFFECT; DRUG METABOLISM; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; LOCUS CERULEUS; MALE; MENTAL DISEASE; NEUROTRANSMISSION; NORADRENALIN BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN INTERACTION; REDUCTION; UPREGULATION;

EID: 0038368136     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)02677-5     Document Type: Article

References (44)

1. Anden N.-E., Grabowska M. Pharmacological evidence for a stimulation of dopamine neurons by noradrenaline neurons in the brain. Eur. J. Pharmacol. 39:1976;275-282.
2. Archer T., Jonsson G., Ross S.B. A parametric study of the effects of the noradrenaline neurotoxin DSP4 on avoidance acquisition and noradrenaline neurones in the CNS of the rat. Br. J. Pharmacol. 82:1984;249-257.
3. Berridge C.W., Dunn A.J. DSP-4-induced depletion of brain norepinephrine produces opposite effects on exploratory behavior 3 and 14 days after treatment. Psychopharmacology. 100:1990;504-508.
4. Claustre Y., Rivy J.P., Dennis T., Scatton B. Pharmacological studies on stress-induced increase in frontal cortical dopamine metabolism in the rat. J. Pharmacol. Exp. Ther. 238:1986;693-700.
5. Creese I., Burt D.R., Snyder S.H. Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity. Science. 197:1977;596-598.
6. Di Chiara G., Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. USA. 85:1988;5274-5278.
7. Eller M., Harro J. Partial denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 potentiates the long-term effect of parachloroamphetamine on 5-hydroxytryptamine metabolism in the rat. Neurosci. Lett. 322:2002;53-56.
8. Fritschy J.-M., Geffard M., Grzanna R. The response of noradrenergic axons to systemically administered DSP-4 in the rat: an immunohistochemical study using antibodies to noradrenaline and dopamine-beta-hydroxylase. J. Chem. Neuroanat. 3:1990;309-321.
9. Fritschy J.-M., Grzanna R. Immunohistochemical analysis of the neurotoxic effects of DSP-4 identifies two populations of noradrenergic axon terminals. Neuroscience. 30:1989;181-197.
10. Gerrits M.A., Petromilli P., Westenberg H.G., Di Chiara G., Van Ree J.M. Decrease in basal dopamine levels in the nucleus accumbens shell during daily drug-seeking behaviour in rats. Brain Res. 924:2002;141-150.
11. Gesi M., Soldani P., Giorgi F.S., Santinami A., Bonaccorsi I., Fornai F. The role of the locus coeruleus in the development of Parkinson's disease. Neurosci. Biobehav. Rev. 24:2000;655-668.
12. Grenhoff J., Nisell M., Ferre S., Aston-Jones G., Svensson T.H. Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat. J. Neural Transm. Gen. Sect. 93:1993;11-25.
13. Grenhoff J., Svensson T.H. Clonidine modulates dopamine cell firing in rat ventral tegmental area. Eur. J. Pharmacol. 165:1989;11-18.
14. Häidkind R., Eller M., Harro M., Kask A., Rinken A., Oreland L., et al. Effects of partial locus coeruleus denervation and chronic mild stress on behaviour and monoamine neurochemistry in the rat. Eur. Neuropsychopharmacol. 13:2003;19-28.
15. Häidkind R., Kivastik T., Eller M., Kolts I., Oreland L., Harro J. Denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 [N (2-chloroethyl)-N-ethyl-2- bromobenzylamine] reduces dopamine release potential in the nucleus accumbens shell in conscious rats. Neurosci. Lett. 332:2002;79-82.
16. Hallman H., Jonsson G. Pharmacological modifications of the neurotoxic action of the noradrenaline neurotoxin DSP4 on central noradrenaline neurons. Eur. J. Pharmacol. 103:1984;269-278.
17. Harro J., Jossan S.S., Oreland L. Changes in cholecystokinin receptor binding in rat brain after selective damage of locus coeruleus projections by DSP-4 treatment. Naunyn Schmiedebergs Arch. Pharmacol. 346:1992;425-431.
18. 2 receptor binding in rats. Pharmacol. Toxicol. 86:2000;197-202.
19. Harro J., Oreland L. Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implication of the locus coeruleus. Brain Res. Rev. 38:2001;79-128.
20. Harro J., Pähkla R., Modiri A.-R., Harro M., Kask A., Oreland L. Dose-dependent effects of noradrenergic denervation by DSP-4 treatment on forced swimming and β-adrenoceptor binding in the rat. J. Neural Transm. 106:1999;619-629.
21. Harro J., Tõnissaar M., Eller M., Kask A., Oreland L. Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry. Brain Res. 899:2001;227-239.
22. Hatip-Al-Khatib I., Mishima K., Iwasaki K., Fujiwara M. Microdialysates of amines and metabolites from core nucleus accumbens of freely moving rats are altered by dizocilpine. Brain Res. 902:2001;108-118.
23. Herve D., Blanc G., Glowinski J., Tassin J.P. Reduction of dopamine utilization in the prefrontal cortex but not in the nucleus accumbens after selective destruction of noradrenergic fibers innervating the ventral tegmental area in the rat. Brain Res. 237:1982;510-516.
24. Hughes Z.A., Stanford S.C. A partial noradrenergic lesion induced by DSP-4 increases extracellular noradrenaline concentration in rat frontal cortex: a microdialysis study in vivo. Psychopharmacology. 136:1998;299-303.
25. Iiri T., Farfel Z., Bourne H.R. G-protein diseases furnish a model for the turn-on switch. Nature. 394:1998;35-38.
26. Jonsson G., Hallman H., Ponzio F., Ross S. DSP4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine): a useful denervation tool for central and peripheral noradrenaline neurons. Eur. J. Pharmacol. 72:1981;173-188.
27. Kask A., Harro J., Tuomainen P., Rägo L., Männisto P.T. Overflow of noradrenaline and dopamine in frontal cortex after [N-(2- chloroethyl)-N-ethyl-2-bromobenzylamine] (DSP-4) treatment: In vivo microdialysis study in anaesthetized rats. Naunyn Schmiedebergs Arch. Pharmacol. 355:1997;267-272.
28. Kuczenski R., Segal D.S. Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. J. Neurochem. 68:1997;2032-2037.
29. Lategan A.J., Marien M.R., Colpaert F.C. Effects of locus coeruleus lesions on the release of endogenous dopamine in the rat nucleus accumbens and caudate nucleus as determined by intracerebral microdialysis. Brain Res. 523:1990;134-138.
30. Lategan A.J., Marien M.R., Colpaert F.C. Suppression of nigrostriatal and mesolimbic dopamine release in vivo following noradrenaline depletion by DSP-4: a microdialysis study. Life Sci. 50:1992;995-999.
31. Mavridis M., Degryse A.D., Lategan A.J., Marien M.R., Colpaert F.C. Effects of locus coeruleus lesions on Parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disease. Neuroscience. 41:1991;507-523.
32. Mishra P.K., Burger R.L., Bettendorf A.F., Browning R.A., Jobe P.C. Role of norepinephrine in forebrain and brainstem seizures: chemical lesioning of locus ceruleus with DSP4. Exp. Neurol. 125:1994;58-64.
33. Morley M.J., Shah K., Bradshaw C.M., Szabadi E. DSP4 and Herrnstein's equation: further evidence for a role of noradrenaline in the maintenance of operant behaviour by positive reinforcement. Psychopharmacology. 96:1988;551-556.
34. Olpe H.R., Laszlo J., Dooley D.J., Heid J., Steinmann M.W. Decreased activity of locus coeruleus neurons in the rat after DSP-4 treatment. Neurosci. Lett. 40:1983;81-84.
35. Peterson G.L. Determination of total protein. Meth. Enzymol. 91:1983;95-119.
36. Pozzi L., Invernizzi R., Cervo L., Vallebuona F., Samanin R. Evidence that extracellular concentrations of dopamine are regulated by noradrenergic neurons in the frontal cortex of rats. J. Neurochem. 63:1994;195-200.
37. Reader T.A., Dewar K.M. Effects of denervation and hyperinnervation on dopamine and serotonin systems in the rat neostriatum: implications for human Parkinson's disease. Neurochem. Int. 34:1999;1-21.
38. 35S]GTPγS binding in rat striatal membranes. Biochem. Pharmacol. 57:1999;155-162.
39. 2 dopamine receptor-G protein coupling. Cross-regulation of agonist and guanosine nucleotide binding sites. Neurosci. Lett. 302:2001;5-8.
40. Ross S.B. Long-term effects of N-2-chlorethyl-N-ethyl-2-bromobenzylamine hydrochloride on noradrenergic neurones in the rat brain and heart. Br. J. Pharmacol. 58:1976;521-527.
41. Tassin J.P., Lavielle S., Herve D., Blanc G., Thierry A.M., Alvarez C., et al. Collateral sprouting and reduced activity of the rat mesocortical dopaminergic neurons after selective destruction of the ascending noradrenergic bundles. Neuroscience. 4:1979;1569-1582.
42. Terasmaa A., Andbjer B., Fuxe K., Rinken A. Striatal dopamine denervation decreases the GDP binding affinity in rat striatal membranes. Neuroreport. 11:2000;2691-2694.
43. Weinshenker D., Miller N.S., Blizinsky K., Laughlin M.L., Palmiter R.D. Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proc. Natl. Acad. Sci. USA. 99:2002;13873-13877.
44. Wolfman C., Abo V., Calvo D., Medina J., Dajas F., Silveira R. Recovery of central noradrenergic neurons one year after the administration of the neurotoxin DSP4. Neurochem. Int. 25:1994;395-400.