Synthesis and neuropharmacological evaluation of R(-)-N-alkyl-11- hydroxynoraporphines and their esters

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 13, 2004, Pages 3553-3559

  Csutoras, Csaba ^a   Zhang, Ao ^a   Zhang, Kehong ^a   Kula, Nora S ^a   Baldessarini, Ross J ^a   Neumeyer, John L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

11 Hydroxyaporphine; Apomorphine; Bioavailability; Dopamine receptor; Motor activity; Parkinson's disease

Indexed keywords

APORPHINE DERIVATIVE; ESTER DERIVATIVE; N ALLYL 11 HYDROXYNORAPORPHINE; N CYCLOPROPYLMETHYL 11 HYDROXYNORAPORPHINE; N ETHYL 11 DOCOSAHEXAENOYLOXYNORAPORPHINE; N ETHYL 11 HYDROXYNORAPORPHINE; N PROPYL 11 ACETYLOXYNORAPORPHINE; N PROPYL 11 DOCOSAHEXAENOYLOXYNORAPORPHINE; N PROPYL 11 HYDROXYNORAPORPHINE; N PROPYL 11 VALERYLOXYNORAPORPHINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG BINDING SITE; DRUG DOSE REGIMEN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MOTOR ACTIVITY; NONHUMAN; PUTAMEN; QUANTITATIVE ANALYSIS; RAT; RECEPTOR AFFINITY;

ALKYLATION; ANIMALS; APORPHINES; ESTERS; MALE; MOLECULAR STRUCTURE; MOTOR ACTIVITY; NEURONS; PROSENCEPHALON; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE;

EID: 2942515205     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.04.029     Document Type: Article

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