Synthesis and neuropharmacological characterization of 2-O-substituted apomorphines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 8, 2008, Pages 4563-4568

  Sipos, Attila ^a   Csutorás, Csaba ^b   Berényi, Sándor ^a   Uustare, Ain ^c   Rinken, Ago ^c  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b ESZTERHÁZY KÁROLY UNIVERSITY   (Hungary)

^c UNIVERSITY OF TARTU   (Estonia)

Author keywords

2 Alkoxyapomorphines; Alkyl type hydroxyl; Apomorphine; Bis apomorphines; D2 D1 receptor selectivity; Dopamine receptor binding activity

Indexed keywords

1,2 BIS [APOMORPHINE 2' OXY]ETHANE; 2 [[APOMORPHINE 2' OXY]ETHOXY] ETHANOL; 2 ALKOXYAPOMORPHINE DERIVATIVE; 2 METHOXYAPOMORPHINE; APOMORPHINE; APOMORPHINE 2 YL (2' HYDROXYETHYL) ETHER; BIS [[APOMORPHINE 2 OXY]ETHYL] ETHER; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; ORIPAVINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHO CELL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; LIPOPHILICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; APOMORPHINE; CATALYSIS; CHO CELLS; CRICETINAE; CRICETULUS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEURONS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 42149166320     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.038     Document Type: Article

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