Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice

Biochemical Pharmacology

Volumn 66, Issue 6, 2003, Pages 1055-1060

  Ochi, Takehiro ^a   Ohkubo, Yoshitaka ^a   Mutoh, Seitaro ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Anti inflammation; Cyclooxygenase 2; FR140423; Prostaglandin formation; Type II collagen arthritis

Indexed keywords

1 [[4,5 BIS(4 METHOXYPHENYL) 2 THIAZOYL]CARBONYL] 4 METHYLPIPERAZINE; 3 (DIFLUOROMETHYL) 1 (4 METHOXYPHENYL) 5 [4 (METHYLSULFINYL)PHENYL]PYRAZOLE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID DERIVATIVE; COLLAGEN TYPE 2; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; FR 122047; INDOMETACIN; ISOENZYME; PROSTAGLANDIN E2; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ANALYSIS; IMMUNIZATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN FUNCTION;

EID: 0043263998     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00420-9     Document Type: Article

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