The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I

Journal of Cell Science

Volumn 122, Issue 7, 2009, Pages 976-984

  Termine, Daniel J ^a   Moremen, Kelley W ^b,c   Sifers, Richard N ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Georgia ^*  (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

Checkpoint activation; Endoplasmic reticulum associated degradation; Unfolded protein response

Indexed keywords

GLYCOPROTEIN; MANNOSIDASE; MANNOSIDASE 1; UNCLASSIFIED DRUG; ALPHA 1 ANTITRYPSIN; EDEM1 PROTEIN, HUMAN; EDEM1 PROTEIN, MOUSE; MANNOSYL OLIGOSACCHARIDE 1,2 ALPHA MANNOSIDASE; MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE; MEMBRANE PROTEIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; EUKARYOTIC CELL; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN TARGETING; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS; ANIMAL; BIOLOGICAL MODEL; CELL LINE; ENZYME STABILITY; ENZYMOLOGY; GENE SILENCING; GENETIC TRANSFECTION; MAMMAL; METABOLISM; MOUSE; PROTEIN BINDING; PROTEIN PROCESSING;

EUKARYOTA; MAMMALIA;

ALPHA 1-ANTITRYPSIN; ANIMALS; CELL LINE; DOWN-REGULATION; ENDOPLASMIC RETICULUM; ENZYME STABILITY; GENE KNOCKDOWN TECHNIQUES; GLYCOPROTEINS; HUMANS; MAMMALS; MANNOSIDASES; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANSFECTION;

EID: 66449084194     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.037291     Document Type: Article

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